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The map label for this gene is btuC [H]

Identifier: 50841596

GI number: 50841596

Start: 126164

End: 127303

Strand: Reverse

Name: btuC [H]

Synonym: PPA0105

Alternate gene names: 50841596

Gene position: 127303-126164 (Counterclockwise)

Preceding gene: 50841597

Following gene: 50841595

Centisome position: 4.97

GC content: 65.18

Gene sequence:

>1140_bases
GTGAGACACAGCCACCAGGAGACGTCGCAGAGCCGAGAGGCACCAGGCCAGGACGTGCGGGATCACCGGGATGTACGAAG
CCGGCAGACGCAGGGGCGGCGCGGGCTGCCGTTGCCGGTACGTTTCACGATCCTCGCAGCGATCTTCGTCGCCGTCACCC
TGGCCGGCCTGGCGTTGGGATCGGTGAACATCCCGTTAGGTGACGTCATGACGGTCGTCACCGGTGGCACCAACGTCGAT
CCCGTCTCGATGACGATCATCCATGACGTCCGAGAGCCTCGCACCATCACCGCCCTGCTCGTCGGGGCGGCGCTGGGAAT
GTCCGGGCTGGAGATGCAGACTCTCTTCCGCAATCCCTTGGCCGACCCGTACGTACTGGGTATCTCGTCGGGTGCCAGTC
TCGGCGTCGCCCTGGTGGTGCTGTCCACCTCGGCATCGGCGGGTGCGGCGACCTTCGCCTCCGGATTGGGCATCGGACCG
GACCTGTTGATCATGGTGGCAGCCGCTCTGGGGGCAGCCGTCGTGCTGCTCATCGTCATGCTGGCAGGACGATTCATCCA
CTCCTCGACGATCCTGCTGCTGCTCGGCGTCATGATCGGGTACTTCGTCTCGTCTGGGGTCACCGTACTGCTGTCGCGGG
CGAGCCCAGAGCTCATTGCCCAGTACACCCGCTGGCAGTTCGGCAGCTACCACGGTGTGACGTGGCAGAACCTGCGAGTC
ATGGTGCCGATCATTGTGGCCATGATCCTCGCCAGCCTGCTGCTCGCCAAGCCGCTTAACGCCTTGTTGCTGGGGGAACG
TTACGCTCAGACGATGGGGATGAACCTCAAGGTGGTGCGCACCCTGCTGGTGGCGAGCACAGCCATCCTCGCCGGTGCCG
CCACCGCGTTCTGCGGGCCGATCGGCTTCCTGGGAATCGCCATTCCCCACCTGACGCGTGGGGTGTTGGGGACGGCCGAT
CATCGTCATCTGCTGCCCGGATGCATCCTCACCGGCAGTTCCCTGGCATTGATGGCCGACATCCTGGCACAGCTGCCCGG
TGACGACGTGCTGCCCGTCAACGCCGTCAACGCAGTTTTCGGGGCGCCGGTCGTCATGGTCATCCTCATCCGCTGGTACC
GGGAGGCGGAGGCGACATGA

Upstream 100 bases:

>100_bases
AAGGCCACCGCGAAGTGACTGCACCTCGGTACATGATGCAGTGCCGTCACGAGAGGCGCGAACGCCCCGAGGCACACCGC
GGACGTATCAGGGGCAACCA

Downstream 100 bases:

>100_bases
CCGGTCTCACACTGTCGAACCTGACGGTCGGGTACCGTTCGGGCCGCCACGTCACGAGGGTGCTGTCGGGGGTGACGGGT
TCGGTGGCTGCCGGGCAGAT

Product: transporter (putative iron (III) permease)

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MRHSHQETSQSREAPGQDVRDHRDVRSRQTQGRRGLPLPVRFTILAAIFVAVTLAGLALGSVNIPLGDVMTVVTGGTNVD
PVSMTIIHDVREPRTITALLVGAALGMSGLEMQTLFRNPLADPYVLGISSGASLGVALVVLSTSASAGAATFASGLGIGP
DLLIMVAAALGAAVVLLIVMLAGRFIHSSTILLLLGVMIGYFVSSGVTVLLSRASPELIAQYTRWQFGSYHGVTWQNLRV
MVPIIVAMILASLLLAKPLNALLLGERYAQTMGMNLKVVRTLLVASTAILAGAATAFCGPIGFLGIAIPHLTRGVLGTAD
HRHLLPGCILTGSSLALMADILAQLPGDDVLPVNAVNAVFGAPVVMVILIRWYREAEAT

Sequences:

>Translated_379_residues
MRHSHQETSQSREAPGQDVRDHRDVRSRQTQGRRGLPLPVRFTILAAIFVAVTLAGLALGSVNIPLGDVMTVVTGGTNVD
PVSMTIIHDVREPRTITALLVGAALGMSGLEMQTLFRNPLADPYVLGISSGASLGVALVVLSTSASAGAATFASGLGIGP
DLLIMVAAALGAAVVLLIVMLAGRFIHSSTILLLLGVMIGYFVSSGVTVLLSRASPELIAQYTRWQFGSYHGVTWQNLRV
MVPIIVAMILASLLLAKPLNALLLGERYAQTMGMNLKVVRTLLVASTAILAGAATAFCGPIGFLGIAIPHLTRGVLGTAD
HRHLLPGCILTGSSLALMADILAQLPGDDVLPVNAVNAVFGAPVVMVILIRWYREAEAT
>Mature_379_residues
MRHSHQETSQSREAPGQDVRDHRDVRSRQTQGRRGLPLPVRFTILAAIFVAVTLAGLALGSVNIPLGDVMTVVTGGTNVD
PVSMTIIHDVREPRTITALLVGAALGMSGLEMQTLFRNPLADPYVLGISSGASLGVALVVLSTSASAGAATFASGLGIGP
DLLIMVAAALGAAVVLLIVMLAGRFIHSSTILLLLGVMIGYFVSSGVTVLLSRASPELIAQYTRWQFGSYHGVTWQNLRV
MVPIIVAMILASLLLAKPLNALLLGERYAQTMGMNLKVVRTLLVASTAILAGAATAFCGPIGFLGIAIPHLTRGVLGTAD
HRHLLPGCILTGSSLALMADILAQLPGDDVLPVNAVNAVFGAPVVMVILIRWYREAEAT

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=300, Percent_Identity=36.3333333333333, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786805, Length=326, Percent_Identity=38.0368098159509, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790740, Length=330, Percent_Identity=32.1212121212121, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1790741, Length=293, Percent_Identity=35.1535836177474, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786804, Length=281, Percent_Identity=32.7402135231317, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=31.5972222222222, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 39699; Mature: 39699

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSHQETSQSREAPGQDVRDHRDVRSRQTQGRRGLPLPVRFTILAAIFVAVTLAGLALG
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
SVNIPLGDVMTVVTGGTNVDPVSMTIIHDVREPRTITALLVGAALGMSGLEMQTLFRNPL
CCCCCHHHHHHEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCC
ADPYVLGISSGASLGVALVVLSTSASAGAATFASGLGIGPDLLIMVAAALGAAVVLLIVM
CCCEEEEECCCCCHHEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LAGRFIHSSTILLLLGVMIGYFVSSGVTVLLSRASPELIAQYTRWQFGSYHGVTWQNLRV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
MVPIIVAMILASLLLAKPLNALLLGERYAQTMGMNLKVVRTLLVASTAILAGAATAFCGP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGFLGIAIPHLTRGVLGTADHRHLLPGCILTGSSLALMADILAQLPGDDVLPVNAVNAVF
HHHHHHHHHHHHHHHHCCCCCCHHCCHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
GAPVVMVILIRWYREAEAT
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHSHQETSQSREAPGQDVRDHRDVRSRQTQGRRGLPLPVRFTILAAIFVAVTLAGLALG
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
SVNIPLGDVMTVVTGGTNVDPVSMTIIHDVREPRTITALLVGAALGMSGLEMQTLFRNPL
CCCCCHHHHHHEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCC
ADPYVLGISSGASLGVALVVLSTSASAGAATFASGLGIGPDLLIMVAAALGAAVVLLIVM
CCCEEEEECCCCCHHEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LAGRFIHSSTILLLLGVMIGYFVSSGVTVLLSRASPELIAQYTRWQFGSYHGVTWQNLRV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
MVPIIVAMILASLLLAKPLNALLLGERYAQTMGMNLKVVRTLLVASTAILAGAATAFCGP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGFLGIAIPHLTRGVLGTADHRHLLPGCILTGSSLALMADILAQLPGDDVLPVNAVNAVF
HHHHHHHHHHHHHHHHCCCCCCHHCCHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
GAPVVMVILIRWYREAEAT
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA