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The map label for this gene is 50841592

Identifier: 50841592

GI number: 50841592

Start: 118209

End: 120173

Strand: Reverse

Name: 50841592

Synonym: PPA0101

Alternate gene names: NA

Gene position: 120173-118209 (Counterclockwise)

Preceding gene: 50841593

Following gene: 50841591

Centisome position: 4.69

GC content: 66.82

Gene sequence:

>1965_bases
ATGACCTATCCGTTCACCGCCGTCGTCGGGCAGGACGAAGCCAGACTCGCTCTGCTGCTGTGCGCGGTCAACCCGCGTAT
CGGTGGGGTCATCCTTAGTGGGGAGAAGGGAACGGCCAAATCGACAGTGGTTCGTGGTCTCGTCGAGCTGTTACCCGGTC
ACATCATGCGCACCCTGGCTCTGGGAACCACCGAGGATCGTCTTGTCGGCGGGTTGGACCTGGAAGCCACCCTGGTGGCG
GGACGCTCCGTCCTCCAGCCGGGTCTGCTTAGCGAGGTCGACGGAGGGGTGCTCTACATCGACGAGGTCAACCTCCTCGA
CGACCACCTCGTCGATCTCGTCATCGACGCCTGCGCCGGGACCGTGCGGGTGGAGCGTGAGGGATTGACGGCCTCCCTGC
CGAGCCGATTCGTGCTGGTGGGAACCATGAACCCCGAGGAGGGGGCACTGCGTCCGCAGTTGTTGGACCGGTTCGGACTG
TGCATCGACGTGCACGGCGAGTCCGACCCGGCCGTCCGGGCTGAGATCATCCGGCGGCGTCTCGACCACGACGCCGATCC
GGCCGAGTTCGACCACCGCTGGCAGAGCGACCAGAACCGTCAGGCCGCAGTCATCGAGAGGGCGCGGCACATCGTCGCCG
GAGTCCGACTGGACGAGGTCGTCACCGAACTCATCTCCTGCCTGTGTCGGCAGAACCACGTTGCTGGGCACCGCGCCGAC
ATCGTCATGGCCGAAGCCACGCGGGCTCATGCCGCCCTGGTCGGTCGCGGCGTCGCCACCGAGGACGACGTGTTAACGAT
CAGCGAGATGGTACTGAGGCACCGCCGTCGCGTCGAGACCCCGTCGGAGTCTCCGCCGCCGCGCAACCAGCACCCCGACG
ATCAGCCGGACCAGCCCGAACAACGTCCCCGGGAACCCGAGCGACCCGACCCCGACGTGGAAAAATGGCAGGCGGGCGAG
AATCTTGCCACGCCGCCCAGCAGTTCAGGCGAACAACAACCCGAATACCACGACGGTCCCCAGAACCAGCGAGACGACGG
CCAGCACGACCCGCGGAAACAACCCTCGGGCAGCGGTGAACAGGTGGTTGCCGCCGGGGACCCGTTCGCCGTCCGCCCCT
TGGAACCTAGTCAGGACCGCTTCGCCCGTCGCGCCTGCGGACGACGTCTGCGCACCCGCAGTAACGATCGACGTGGCCGC
TACGTCTCAGCCCGACCCACCGACCGCCCTGACGACCTCGCCCTGGACGCCACCCTTCGCGCGGCGGCGGTTCATCAGAA
GTCACGTCGGGCCACCGAGCGTCCAGACCTGGCGGTGCACGTCAAACCGATCGACTGGCGGGCCAAAGTACGGGCCGGAC
GAGCCGCCTCCTGCGTGATCTTCGTAGTCGACGCTTCCGGGTCGATGGGGTCACGAGGACGAATGACCGCCTCTAAGGGG
GCCGTGCTGTCCCTCCTCTTGGACGCCTACGTCAAGCGTGATCGGGTGTGCCTTATCGGTTTCCGCCGCGACCGGGCCGA
GGTGCTGGTGCCGGTGACCTCCTCGGTGGAGGTAGCCCAGCACGGTTTGGCAGAGCTACCGGTCGGTGGGCGCACCCCGC
TGTCGGCCGGACTGATTAAGGCCTGCGAGGTGGTACGGCCCCTGCTCCTCAAGGACCCCGGGCTGCGACCATTACTCATC
CTCGTCACCGACGGGCGCGGCAACGTCAGTCTGGACGGCCGTCCCAACTCCCAGGCCACCGATGAGGCGATTCGGGTGGC
AACCAAGCTCGGCGTCGACACACGACTCAGCTGGGTCGTCATCGACACCGAGGACCCACGAGGTATCCAGCTGTCTCGGG
CCCGCGACATTGCCACAGCCTTGGGTGGACCTTGTCTGCGCATCGACGACCTGCGGGCTGACGACCTCGTCAACGTCGTC
TCTCGACTTGACCCCTCCCACCAATCTCCCCGAAAGGACCGCTGA

Upstream 100 bases:

>100_bases
AGGTCTCCGACGACCCCGCGATCGCCCCGAACACCCGGGTGGGTGCGCCTCCGCAGAACCCTGCCGGTGGACTTGACCTG
TCCGAGCTGGGGTTGATCTA

Downstream 100 bases:

>100_bases
CATGGCACAACGCCCCGTCTATCCCTTCTGCGCCATCGTCGGTCAGGAGGAGATGAAGCTGGCTCTCATCCTCGCTACCA
TCAGCCCCGATTTGTCCGGG

Product: magnesium-chelatase 67 kDa subunit

Products: ADP; phosphate; Mg-protoporphyrin IX; H+

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 653

Protein sequence:

>654_residues
MTYPFTAVVGQDEARLALLLCAVNPRIGGVILSGEKGTAKSTVVRGLVELLPGHIMRTLALGTTEDRLVGGLDLEATLVA
GRSVLQPGLLSEVDGGVLYIDEVNLLDDHLVDLVIDACAGTVRVEREGLTASLPSRFVLVGTMNPEEGALRPQLLDRFGL
CIDVHGESDPAVRAEIIRRRLDHDADPAEFDHRWQSDQNRQAAVIERARHIVAGVRLDEVVTELISCLCRQNHVAGHRAD
IVMAEATRAHAALVGRGVATEDDVLTISEMVLRHRRRVETPSESPPPRNQHPDDQPDQPEQRPREPERPDPDVEKWQAGE
NLATPPSSSGEQQPEYHDGPQNQRDDGQHDPRKQPSGSGEQVVAAGDPFAVRPLEPSQDRFARRACGRRLRTRSNDRRGR
YVSARPTDRPDDLALDATLRAAAVHQKSRRATERPDLAVHVKPIDWRAKVRAGRAASCVIFVVDASGSMGSRGRMTASKG
AVLSLLLDAYVKRDRVCLIGFRRDRAEVLVPVTSSVEVAQHGLAELPVGGRTPLSAGLIKACEVVRPLLLKDPGLRPLLI
LVTDGRGNVSLDGRPNSQATDEAIRVATKLGVDTRLSWVVIDTEDPRGIQLSRARDIATALGGPCLRIDDLRADDLVNVV
SRLDPSHQSPRKDR

Sequences:

>Translated_654_residues
MTYPFTAVVGQDEARLALLLCAVNPRIGGVILSGEKGTAKSTVVRGLVELLPGHIMRTLALGTTEDRLVGGLDLEATLVA
GRSVLQPGLLSEVDGGVLYIDEVNLLDDHLVDLVIDACAGTVRVEREGLTASLPSRFVLVGTMNPEEGALRPQLLDRFGL
CIDVHGESDPAVRAEIIRRRLDHDADPAEFDHRWQSDQNRQAAVIERARHIVAGVRLDEVVTELISCLCRQNHVAGHRAD
IVMAEATRAHAALVGRGVATEDDVLTISEMVLRHRRRVETPSESPPPRNQHPDDQPDQPEQRPREPERPDPDVEKWQAGE
NLATPPSSSGEQQPEYHDGPQNQRDDGQHDPRKQPSGSGEQVVAAGDPFAVRPLEPSQDRFARRACGRRLRTRSNDRRGR
YVSARPTDRPDDLALDATLRAAAVHQKSRRATERPDLAVHVKPIDWRAKVRAGRAASCVIFVVDASGSMGSRGRMTASKG
AVLSLLLDAYVKRDRVCLIGFRRDRAEVLVPVTSSVEVAQHGLAELPVGGRTPLSAGLIKACEVVRPLLLKDPGLRPLLI
LVTDGRGNVSLDGRPNSQATDEAIRVATKLGVDTRLSWVVIDTEDPRGIQLSRARDIATALGGPCLRIDDLRADDLVNVV
SRLDPSHQSPRKDR
>Mature_653_residues
TYPFTAVVGQDEARLALLLCAVNPRIGGVILSGEKGTAKSTVVRGLVELLPGHIMRTLALGTTEDRLVGGLDLEATLVAG
RSVLQPGLLSEVDGGVLYIDEVNLLDDHLVDLVIDACAGTVRVEREGLTASLPSRFVLVGTMNPEEGALRPQLLDRFGLC
IDVHGESDPAVRAEIIRRRLDHDADPAEFDHRWQSDQNRQAAVIERARHIVAGVRLDEVVTELISCLCRQNHVAGHRADI
VMAEATRAHAALVGRGVATEDDVLTISEMVLRHRRRVETPSESPPPRNQHPDDQPDQPEQRPREPERPDPDVEKWQAGEN
LATPPSSSGEQQPEYHDGPQNQRDDGQHDPRKQPSGSGEQVVAAGDPFAVRPLEPSQDRFARRACGRRLRTRSNDRRGRY
VSARPTDRPDDLALDATLRAAAVHQKSRRATERPDLAVHVKPIDWRAKVRAGRAASCVIFVVDASGSMGSRGRMTASKGA
VLSLLLDAYVKRDRVCLIGFRRDRAEVLVPVTSSVEVAQHGLAELPVGGRTPLSAGLIKACEVVRPLLLKDPGLRPLLIL
VTDGRGNVSLDGRPNSQATDEAIRVATKLGVDTRLSWVVIDTEDPRGIQLSRARDIATALGGPCLRIDDLRADDLVNVVS
RLDPSHQSPRKDR

Specific function: Unknown

COG id: COG1239

COG function: function code H; Mg-chelatase subunit ChlI

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011704
- InterPro:   IPR012804
- InterPro:   IPR002035 [H]

Pfam domain/function: PF07728 AAA_5; PF00092 VWA [H]

EC number: 6.6.1.1

Molecular weight: Translated: 71384; Mature: 71253

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPFTAVVGQDEARLALLLCAVNPRIGGVILSGEKGTAKSTVVRGLVELLPGHIMRTLA
CCCCEEEEECCCCCEEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LGTTEDRLVGGLDLEATLVAGRSVLQPGLLSEVDGGVLYIDEVNLLDDHLVDLVIDACAG
CCCCHHHEECCCCCEEHHHHCHHHHCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHCCC
TVRVEREGLTASLPSRFVLVGTMNPEEGALRPQLLDRFGLCIDVHGESDPAVRAEIIRRR
CEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHHHHH
LDHDADPAEFDHRWQSDQNRQAAVIERARHIVAGVRLDEVVTELISCLCRQNHVAGHRAD
HCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCE
IVMAEATRAHAALVGRGVATEDDVLTISEMVLRHRRRVETPSESPPPRNQHPDDQPDQPE
EEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
QRPREPERPDPDVEKWQAGENLATPPSSSGEQQPEYHDGPQNQRDDGQHDPRKQPSGSGE
HCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QVVAAGDPFAVRPLEPSQDRFARRACGRRLRTRSNDRRGRYVSARPTDRPDDLALDATLR
EEEECCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEHHHHHH
AAAVHQKSRRATERPDLAVHVKPIDWRAKVRAGRAASCVIFVVDASGSMGSRGRMTASKG
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCH
AVLSLLLDAYVKRDRVCLIGFRRDRAEVLVPVTSSVEVAQHGLAELPVGGRTPLSAGLIK
HHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHCCHHHCCCCCCCCHHHHHHH
ACEVVRPLLLKDPGLRPLLILVTDGRGNVSLDGRPNSQATDEAIRVATKLGVDTRLSWVV
HHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEE
IDTEDPRGIQLSRARDIATALGGPCLRIDDLRADDLVNVVSRLDPSHQSPRKDR
EECCCCCCEEHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TYPFTAVVGQDEARLALLLCAVNPRIGGVILSGEKGTAKSTVVRGLVELLPGHIMRTLA
CCCEEEEECCCCCEEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LGTTEDRLVGGLDLEATLVAGRSVLQPGLLSEVDGGVLYIDEVNLLDDHLVDLVIDACAG
CCCCHHHEECCCCCEEHHHHCHHHHCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHCCC
TVRVEREGLTASLPSRFVLVGTMNPEEGALRPQLLDRFGLCIDVHGESDPAVRAEIIRRR
CEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHHHHH
LDHDADPAEFDHRWQSDQNRQAAVIERARHIVAGVRLDEVVTELISCLCRQNHVAGHRAD
HCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCE
IVMAEATRAHAALVGRGVATEDDVLTISEMVLRHRRRVETPSESPPPRNQHPDDQPDQPE
EEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
QRPREPERPDPDVEKWQAGENLATPPSSSGEQQPEYHDGPQNQRDDGQHDPRKQPSGSGE
HCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QVVAAGDPFAVRPLEPSQDRFARRACGRRLRTRSNDRRGRYVSARPTDRPDDLALDATLR
EEEECCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEHHHHHH
AAAVHQKSRRATERPDLAVHVKPIDWRAKVRAGRAASCVIFVVDASGSMGSRGRMTASKG
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCH
AVLSLLLDAYVKRDRVCLIGFRRDRAEVLVPVTSSVEVAQHGLAELPVGGRTPLSAGLIK
HHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHCCHHHCCCCCCCCHHHHHHH
ACEVVRPLLLKDPGLRPLLILVTDGRGNVSLDGRPNSQATDEAIRVATKLGVDTRLSWVV
HHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEE
IDTEDPRGIQLSRARDIATALGGPCLRIDDLRADDLVNVVSRLDPSHQSPRKDR
EECCCCCCEEHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; protoporphyrin IX; Mg2+; H2O

Specific reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]