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The map label for this gene is nrnA [H]

Identifier: 50365305

GI number: 50365305

Start: 571307

End: 572251

Strand: Reverse

Name: nrnA [H]

Synonym: Mfl488

Alternate gene names: 50365305

Gene position: 572251-571307 (Counterclockwise)

Preceding gene: 50365306

Following gene: 50365304

Centisome position: 72.14

GC content: 29.74

Gene sequence:

>945_bases
ATGACAATTTATAAACAAATAAAACAAGTTATAGAAAAATATGACAAGATAATTATTTTAAGACATATTGTTCCAGATGG
AGATGCTTATGGTTCACAATTAGGCTTAAAAGAATTAATTAAAACAAATTACCCAAATAAAGAAGTTTATGCATTTGGTG
AAGAAATTGGATATTTAAAACATGCTGGAACACCTGATGTTTTTACAGATGAAGCAATATTTAAGGATGCATTAGTTATT
GTAACTGATTGTGGTAATGTTGAAAGAATTGATAATCAAAATTATGATAAGGGTGCATTTTTACTAAAAATTGATCACCA
CCCAGATGCAACACCATATGGAGATCTATCATGAGTTGATGTAAATTATACAAGTGCAAGTGAAATGGTTGGAGATTTAG
CTGTTAATAATAACTGAGAAATAACACCAGTTGCAGCTAGAGTAATTTATCATGGAATTTGTACAGACAGTGGAAGATTT
TTATTTGGTGGTATTACACCAAGAACTTTTGAAGTATGTGCTAGATTAATTGAGACAGGTTTTGATGTGTTTGAAATGTA
TAAAACTATGTACAAACGTTCATTCCCAGTTTTAGCTTTACAATCAGAATTAATAGCATCAGCTAAAGTTACTGATCACA
AAGTTGGATATATCATCTTACCAGATGAGTTAATGAAAAAATATAATTTAAGTTATGAAGAAAATGGTAAATTTTCAAAC
TTATTAAAAGACTTAGAAGGAATTGACATTTGAATCACTTTCTCAATCAGAGAAGATGGAAAATGAAGAGTTGAATTCCG
TTCAAATGGTATTGCAGTTAATGAATTAGCTGTTAAATGAGGTGGAGGTGGTCACAAAATGGCTGCTGGAGCAATCATTA
ACAGTTTAGATGAAGCAATGCAAATTGTTGAAGATGCAAATCAAATAATAATTGATAATGAATAG

Upstream 100 bases:

>100_bases
TTAATAAAAATTAGTAATTCCGTAAGGAATTGCTTTTTTTATTGTAAAATAAAAAGTTCTATCAAATAGTTGGTAAAATA
TTAATAATATAAGGAGAATT

Downstream 100 bases:

>100_bases
ACCACATATAATGTGGTTTTGCTAAAATAAGATAAAAGATAAGGTGATAAAATGAGTATATTTATAATAATATTTGTAAT
AATTTTAGCTGTAGGACTGA

Product: exopolyphosphatase-like

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTIYKQIKQVIEKYDKIIILRHIVPDGDAYGSQLGLKELIKTNYPNKEVYAFGEEIGYLKHAGTPDVFTDEAIFKDALVI
VTDCGNVERIDNQNYDKGAFLLKIDHHPDATPYGDLSWVDVNYTSASEMVGDLAVNNNWEITPVAARVIYHGICTDSGRF
LFGGITPRTFEVCARLIETGFDVFEMYKTMYKRSFPVLALQSELIASAKVTDHKVGYIILPDELMKKYNLSYEENGKFSN
LLKDLEGIDIWITFSIREDGKWRVEFRSNGIAVNELAVKWGGGGHKMAAGAIINSLDEAMQIVEDANQIIIDNE

Sequences:

>Translated_314_residues
MTIYKQIKQVIEKYDKIIILRHIVPDGDAYGSQLGLKELIKTNYPNKEVYAFGEEIGYLKHAGTPDVFTDEAIFKDALVI
VTDCGNVERIDNQNYDKGAFLLKIDHHPDATPYGDLS*VDVNYTSASEMVGDLAVNNN*EITPVAARVIYHGICTDSGRF
LFGGITPRTFEVCARLIETGFDVFEMYKTMYKRSFPVLALQSELIASAKVTDHKVGYIILPDELMKKYNLSYEENGKFSN
LLKDLEGIDI*ITFSIREDGK*RVEFRSNGIAVNELAVK*GGGGHKMAAGAIINSLDEAMQIVEDANQIIIDNE
>Mature_313_residues
TIYKQIKQVIEKYDKIIILRHIVPDGDAYGSQLGLKELIKTNYPNKEVYAFGEEIGYLKHAGTPDVFTDEAIFKDALVIV
TDCGNVERIDNQNYDKGAFLLKIDHHPDATPYGDLS*VDVNYTSASEMVGDLAVNNN*EITPVAARVIYHGICTDSGRFL
FGGITPRTFEVCARLIETGFDVFEMYKTMYKRSFPVLALQSELIASAKVTDHKVGYIILPDELMKKYNLSYEENGKFSNL
LKDLEGIDI*ITFSIREDGK*RVEFRSNGIAVNELAVK*GGGGHKMAAGAIINSLDEAMQIVEDANQIIIDNE

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 34345; Mature: 34213

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYKQIKQVIEKYDKIIILRHIVPDGDAYGSQLGLKELIKTNYPNKEVYAFGEEIGYLK
CCHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
HAGTPDVFTDEAIFKDALVIVTDCGNVERIDNQNYDKGAFLLKIDHHPDATPYGDLSVDV
CCCCCCCCCCHHHHCCEEEEEECCCCCEECCCCCCCCCEEEEEEECCCCCCCCCCEEEEE
NYTSASEMVGDLAVNNNEITPVAARVIYHGICTDSGRFLFGGITPRTFEVCARLIETGFD
ECCCHHHHHHHHEECCCCCCHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHHHHHCCHH
VFEMYKTMYKRSFPVLALQSELIASAKVTDHKVGYIILPDELMKKYNLSYEENGKFSNLL
HHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHH
KDLEGIDIITFSIREDGKRVEFRSNGIAVNELAVKGGGGHKMAAGAIINSLDEAMQIVED
HHCCCCEEEEEEECCCCCEEEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
ANQIIIDNE
CCEEEEECC
>Mature Secondary Structure 
TIYKQIKQVIEKYDKIIILRHIVPDGDAYGSQLGLKELIKTNYPNKEVYAFGEEIGYLK
CHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
HAGTPDVFTDEAIFKDALVIVTDCGNVERIDNQNYDKGAFLLKIDHHPDATPYGDLSVDV
CCCCCCCCCCHHHHCCEEEEEECCCCCEECCCCCCCCCEEEEEEECCCCCCCCCCEEEEE
NYTSASEMVGDLAVNNNEITPVAARVIYHGICTDSGRFLFGGITPRTFEVCARLIETGFD
ECCCHHHHHHHHEECCCCCCHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHHHHHCCHH
VFEMYKTMYKRSFPVLALQSELIASAKVTDHKVGYIILPDELMKKYNLSYEENGKFSNLL
HHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHH
KDLEGIDIITFSIREDGKRVEFRSNGIAVNELAVKGGGGHKMAAGAIINSLDEAMQIVED
HHCCCCEEEEEEECCCCCEEEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
ANQIIIDNE
CCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]