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The map label for this gene is gcp [H]

Identifier: 50365301

GI number: 50365301

Start: 568949

End: 569902

Strand: Reverse

Name: gcp [H]

Synonym: Mfl484

Alternate gene names: 50365301

Gene position: 569902-568949 (Counterclockwise)

Preceding gene: 50365302

Following gene: 50365300

Centisome position: 71.85

GC content: 29.98

Gene sequence:

>954_bases
ATGAAAATATTAGCAATTGAATCAAGTTGTGATGAATTTTCAATTTCAATAATTGATGATGGAAAAATATTAACAAATAT
TATTTCATCACAAATAGATCAACACGTTAATTTTGGTGGTGTTGTTCCTGAACTAGCTGCAAGACTACATTTAGAAAATA
TATCTTGAGTAATCAAATCTGCACTTGAATCTTCAAATACAAAAATTGAAGAAATTGATCATGTTGCATATACTGAAAAA
CCTGGTTTAATAGGTTCTTTAATCATAGGTAAATTAGTTGCTGAAACTATCGCTAGTTATATTGATAAACCATTAATGCC
ATTACATCATATTGAAGGTCACATTTATGGAGCATCAATTGAGAATGAGTTTGTTTATCCGGTACTAGCTATGGTTGTTA
GTGGAGGACATACGCAAATTGAAATCGTTAACTCACCTAATGAATTTGAGGTAATTGGTGCAACTCTTGATGATGCTATT
GGTGAATGTTATGACAAGGTAGCTAGAGTAATGGGATTAGGTTATCCGGGTGGACCAAAAATTGACAAATTGGCTCAAAA
AGGAAATAAAGAAGCTTTTATATTTCCTATATCTAAAAATGATGATAGTTATGACTTTTCATATTCAGGATTAAAAACAG
CAGTCATTAATATTATTCATAATTTAACTCAAAAAGGTGAGGAAATACCGGTTGCAGATATTGCTGCTAGTTTTCAATAT
GCAGCAACAAAAATAGTTGAAAAAAAACTAGAAAAAGCAATTATTCAATTTAAACCAAAAACATTAACAGTTGCTGGTGG
TGTTAGTGCTAATAGTGAAATTAGAAACATAATAATGTCATTGGGTAAAAAATATAATATAACAAACACATTTGTTCCAA
AGATGGAATATTGCACAGATAATGCAGCAATGATAGCGAAATTAGCGTACGAAAAGTTGAAAAGTAGTAATTAA

Upstream 100 bases:

>100_bases
TAAAATAGATTACTTACATACTGAAGTTGCACAAAAATTCGGATATAACATATCAAAAATGTATGATGAGTTTATTAAAT
CATTATAAAAAGGAGAACAC

Downstream 100 bases:

>100_bases
TTTCCAAAAATGATAAAATATAATAAATAAATATGCAAAAATGCATAATTTTACAACGGAGGAAATATGAGATCTTTTTT
AGCAAAACTTTCAACAATTG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKILAIESSCDEFSISIIDDGKILTNIISSQIDQHVNFGGVVPELAARLHLENISWVIKSALESSNTKIEEIDHVAYTEK
PGLIGSLIIGKLVAETIASYIDKPLMPLHHIEGHIYGASIENEFVYPVLAMVVSGGHTQIEIVNSPNEFEVIGATLDDAI
GECYDKVARVMGLGYPGGPKIDKLAQKGNKEAFIFPISKNDDSYDFSYSGLKTAVINIIHNLTQKGEEIPVADIAASFQY
AATKIVEKKLEKAIIQFKPKTLTVAGGVSANSEIRNIIMSLGKKYNITNTFVPKMEYCTDNAAMIAKLAYEKLKSSN

Sequences:

>Translated_317_residues
MKILAIESSCDEFSISIIDDGKILTNIISSQIDQHVNFGGVVPELAARLHLENIS*VIKSALESSNTKIEEIDHVAYTEK
PGLIGSLIIGKLVAETIASYIDKPLMPLHHIEGHIYGASIENEFVYPVLAMVVSGGHTQIEIVNSPNEFEVIGATLDDAI
GECYDKVARVMGLGYPGGPKIDKLAQKGNKEAFIFPISKNDDSYDFSYSGLKTAVINIIHNLTQKGEEIPVADIAASFQY
AATKIVEKKLEKAIIQFKPKTLTVAGGVSANSEIRNIIMSLGKKYNITNTFVPKMEYCTDNAAMIAKLAYEKLKSSN
>Mature_317_residues
MKILAIESSCDEFSISIIDDGKILTNIISSQIDQHVNFGGVVPELAARLHLENIS*VIKSALESSNTKIEEIDHVAYTEK
PGLIGSLIIGKLVAETIASYIDKPLMPLHHIEGHIYGASIENEFVYPVLAMVVSGGHTQIEIVNSPNEFEVIGATLDDAI
GECYDKVARVMGLGYPGGPKIDKLAQKGNKEAFIFPISKNDDSYDFSYSGLKTAVINIIHNLTQKGEEIPVADIAASFQY
AATKIVEKKLEKAIIQFKPKTLTVAGGVSANSEIRNIIMSLGKKYNITNTFVPKMEYCTDNAAMIAKLAYEKLKSSN

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=336, Percent_Identity=32.4404761904762, Blast_Score=168, Evalue=5e-42,
Organism=Homo sapiens, GI8923380, Length=317, Percent_Identity=27.1293375394322, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1789445, Length=319, Percent_Identity=41.3793103448276, Blast_Score=251, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI17557464, Length=322, Percent_Identity=31.3664596273292, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71995670, Length=312, Percent_Identity=29.1666666666667, Blast_Score=120, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=348, Percent_Identity=29.5977011494253, Blast_Score=112, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6322891, Length=285, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=8e-20,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=31.4705882352941, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21357207, Length=324, Percent_Identity=28.0864197530864, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 34390; Mature: 34390

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILAIESSCDEFSISIIDDGKILTNIISSQIDQHVNFGGVVPELAARLHLENISVIKSA
CEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LESSNTKIEEIDHVAYTEKPGLIGSLIIGKLVAETIASYIDKPLMPLHHIEGHIYGASIE
HHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCC
NEFVYPVLAMVVSGGHTQIEIVNSPNEFEVIGATLDDAIGECYDKVARVMGLGYPGGPKI
CCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCH
DKLAQKGNKEAFIFPISKNDDSYDFSYSGLKTAVINIIHNLTQKGEEIPVADIAASFQYA
HHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ATKIVEKKLEKAIIQFKPKTLTVAGGVSANSEIRNIIMSLGKKYNITNTFVPKMEYCTDN
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
AAMIAKLAYEKLKSSN
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILAIESSCDEFSISIIDDGKILTNIISSQIDQHVNFGGVVPELAARLHLENISVIKSA
CEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LESSNTKIEEIDHVAYTEKPGLIGSLIIGKLVAETIASYIDKPLMPLHHIEGHIYGASIE
HHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCC
NEFVYPVLAMVVSGGHTQIEIVNSPNEFEVIGATLDDAIGECYDKVARVMGLGYPGGPKI
CCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCH
DKLAQKGNKEAFIFPISKNDDSYDFSYSGLKTAVINIIHNLTQKGEEIPVADIAASFQYA
HHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ATKIVEKKLEKAIIQFKPKTLTVAGGVSANSEIRNIIMSLGKKYNITNTFVPKMEYCTDN
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
AAMIAKLAYEKLKSSN
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA