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The map label for this gene is asnC [H]

Identifier: 50365297

GI number: 50365297

Start: 564720

End: 566084

Strand: Reverse

Name: asnC [H]

Synonym: Mfl480

Alternate gene names: 50365297

Gene position: 566084-564720 (Counterclockwise)

Preceding gene: 50365298

Following gene: 50365296

Centisome position: 71.36

GC content: 29.38

Gene sequence:

>1365_bases
ATGGATATTAAATTTTTATATGACAACCATGAAACTTTAAAAGAACAAAAAGTAACAATCATTGGTAGAGTTAGATCAAA
TCGTCAAGGAAAAGCAGTTAGCTTTATGGTTTTAAATGATGGAACTGTTTTAAATGACTTACAAGTTGTTTATAAACCAG
AAACATTTGGTTTTGAACAAGGAAGTAAAGCAAGAGTTAGTTCAATTGTTGAAATCGAAGGTATTTTAATTCCTACACCA
ACAAGACCACAACCTTTTGAAATTAATGCGACTTCAATTACTTTACTTGATCAAGCAATTGAAGAATATCCATTACAAAA
AAAAGAACATTCTCCTGAATTTTTAAGAGAAATTTCGCACTTAAGAGCTAGAACAAAAACATTCCAAGCAATTTTTAGAA
TTCGCTCAACAGCTGCTTTTGCAATTCATAAATTCTTTCAAGAAAATAACTATGTTTATGTTACAACACCAATCATAACT
TCAAATGATGCTGAAGGTGCTGGTGAACAATTCGTAGTTACAGTTAATGAAGATAAAGATTATGCAAATGACTTTTTTGG
TAAAAAAGCTAGTTTAACAGTTTCAGGACAATTAAATGGTGAAGCATTTGCTCAAGCATTTAAAAATATCTATACTTTTG
GACCAACATTCAGAGCTGAAAACTCACATACAACAAAACATGCTTCAGAATTCTGAATGATAGAACCAGAAGTTGCTTTT
GCAGATATTAATGACAACATTCAATTAATGCAAGATATGTTAAAAAGTGTTGTTGGTTATGTTTTAGAAAAAAACATGAC
TGAATTAGAATTTTTACAAGAACAATTAGAACCTGGTTTAATTGATAAAATAACAGGAATTGTTAATGTTGAATTTAAAG
TTAATACTTATGAAGAAGTTTTAAAAACATTACAAGATGCTATTGATAAAGGGCATAAATTTGAAGAAAACAATATTCAT
TTTGGTTTAGATTTAGGTACAGAACACGAAAGATTTATTTGTGAAGAAGTTAACAAATGTCCAACATTTGTTATCAACTA
TCCAAAAGATATTAAATCATTTTACATGAAACAAAATGATGATGGTAAAACAGTTGCCGCTGTAGACTTACTAGTTCCAG
GAATTGGTGAATTATGTGGTGGAAGTGAACGTGAAGCTAACTTAGATAAGATTCTTGAGAGATGTGAATTCTATGGAATT
AATCCTGAAGAATTAGACTGATACATTGGATTAAGAAAATATGGATTTTACAAATCTGCTGGATTTGGTTTAGGGTTTGA
AAGATTAATTATGTACATTACAGGTGCTTCAAACATTAGAGATGTTATTCCATTCCCAAGAACACCTAAAACATTATTGT
ATTAA

Upstream 100 bases:

>100_bases
CCAGCAATTAAAAAAATAGCAAAATTTGAAACTGATACAAACCTTAATGGTGGAGTTGGTAAATTTATAGAAAAATATGT
ATTAAAAGGAGAATAAAGAT

Downstream 100 bases:

>100_bases
TATATAAATATATTCAAAAATGCCTTGCGGCATTTTTATTTTGAATATTAAGTTTGGTATAATAAATAAAGATTAAAACT
GGAGGTATGCATATGGCATT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MDIKFLYDNHETLKEQKVTIIGRVRSNRQGKAVSFMVLNDGTVLNDLQVVYKPETFGFEQGSKARVSSIVEIEGILIPTP
TRPQPFEINATSITLLDQAIEEYPLQKKEHSPEFLREISHLRARTKTFQAIFRIRSTAAFAIHKFFQENNYVYVTTPIIT
SNDAEGAGEQFVVTVNEDKDYANDFFGKKASLTVSGQLNGEAFAQAFKNIYTFGPTFRAENSHTTKHASEFWMIEPEVAF
ADINDNIQLMQDMLKSVVGYVLEKNMTELEFLQEQLEPGLIDKITGIVNVEFKVNTYEEVLKTLQDAIDKGHKFEENNIH
FGLDLGTEHERFICEEVNKCPTFVINYPKDIKSFYMKQNDDGKTVAAVDLLVPGIGELCGGSEREANLDKILERCEFYGI
NPEELDWYIGLRKYGFYKSAGFGLGFERLIMYITGASNIRDVIPFPRTPKTLLY

Sequences:

>Translated_454_residues
MDIKFLYDNHETLKEQKVTIIGRVRSNRQGKAVSFMVLNDGTVLNDLQVVYKPETFGFEQGSKARVSSIVEIEGILIPTP
TRPQPFEINATSITLLDQAIEEYPLQKKEHSPEFLREISHLRARTKTFQAIFRIRSTAAFAIHKFFQENNYVYVTTPIIT
SNDAEGAGEQFVVTVNEDKDYANDFFGKKASLTVSGQLNGEAFAQAFKNIYTFGPTFRAENSHTTKHASEF*MIEPEVAF
ADINDNIQLMQDMLKSVVGYVLEKNMTELEFLQEQLEPGLIDKITGIVNVEFKVNTYEEVLKTLQDAIDKGHKFEENNIH
FGLDLGTEHERFICEEVNKCPTFVINYPKDIKSFYMKQNDDGKTVAAVDLLVPGIGELCGGSEREANLDKILERCEFYGI
NPEELD*YIGLRKYGFYKSAGFGLGFERLIMYITGASNIRDVIPFPRTPKTLLY
>Mature_454_residues
MDIKFLYDNHETLKEQKVTIIGRVRSNRQGKAVSFMVLNDGTVLNDLQVVYKPETFGFEQGSKARVSSIVEIEGILIPTP
TRPQPFEINATSITLLDQAIEEYPLQKKEHSPEFLREISHLRARTKTFQAIFRIRSTAAFAIHKFFQENNYVYVTTPIIT
SNDAEGAGEQFVVTVNEDKDYANDFFGKKASLTVSGQLNGEAFAQAFKNIYTFGPTFRAENSHTTKHASEF*MIEPEVAF
ADINDNIQLMQDMLKSVVGYVLEKNMTELEFLQEQLEPGLIDKITGIVNVEFKVNTYEEVLKTLQDAIDKGHKFEENNIH
FGLDLGTEHERFICEEVNKCPTFVINYPKDIKSFYMKQNDDGKTVAAVDLLVPGIGELCGGSEREANLDKILERCEFYGI
NPEELD*YIGLRKYGFYKSAGFGLGFERLIMYITGASNIRDVIPFPRTPKTLLY

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=446, Percent_Identity=40.8071748878924, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI4758762, Length=444, Percent_Identity=29.0540540540541, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI45439306, Length=337, Percent_Identity=27.299703264095, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1787161, Length=450, Percent_Identity=44.8888888888889, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1789256, Length=470, Percent_Identity=24.6808510638298, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17556372, Length=420, Percent_Identity=31.9047619047619, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI71984122, Length=452, Percent_Identity=29.4247787610619, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17551876, Length=341, Percent_Identity=28.7390029325513, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319872, Length=479, Percent_Identity=37.3695198329854, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6321807, Length=450, Percent_Identity=27.7777777777778, Blast_Score=166, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6323011, Length=472, Percent_Identity=27.1186440677966, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19922416, Length=451, Percent_Identity=34.589800443459, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI19921528, Length=450, Percent_Identity=28.6666666666667, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17136276, Length=471, Percent_Identity=26.1146496815287, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 51324; Mature: 51324

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKFLYDNHETLKEQKVTIIGRVRSNRQGKAVSFMVLNDGTVLNDLQVVYKPETFGFEQ
CCEEEEECCHHHHHHCCEEEEEEECCCCCCCEEEEEEEECCCEEECEEEEECCCCCCCCC
GSKARVSSIVEIEGILIPTPTRPQPFEINATSITLLDQAIEEYPLQKKEHSPEFLREISH
CCHHHHHHEEEECEEEECCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LRARTKTFQAIFRIRSTAAFAIHKFFQENNYVYVTTPIITSNDAEGAGEQFVVTVNEDKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEECCCCCCCCCEEEEEEECCCC
YANDFFGKKASLTVSGQLNGEAFAQAFKNIYTFGPTFRAENSHTTKHASEFMIEPEVAFA
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHEECCCEEEE
DINDNIQLMQDMLKSVVGYVLEKNMTELEFLQEQLEPGLIDKITGIVNVEFKVNTYEEVL
ECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCEEEEEEEECCHHHHH
KTLQDAIDKGHKFEENNIHFGLDLGTEHERFICEEVNKCPTFVINYPKDIKSFYMKQNDD
HHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCC
GKTVAAVDLLVPGIGELCGGSEREANLDKILERCEFYGINPEELDYIGLRKYGFYKSAGF
CCEEEEEEHHHCCCHHHCCCCCCCCCHHHHHHHHHHCCCCHHHCCEEECHHCCCCCCCCC
GLGFERLIMYITGASNIRDVIPFPRTPKTLLY
CCCHHHHEEEEECCCCCHHCCCCCCCCHHHCC
>Mature Secondary Structure
MDIKFLYDNHETLKEQKVTIIGRVRSNRQGKAVSFMVLNDGTVLNDLQVVYKPETFGFEQ
CCEEEEECCHHHHHHCCEEEEEEECCCCCCCEEEEEEEECCCEEECEEEEECCCCCCCCC
GSKARVSSIVEIEGILIPTPTRPQPFEINATSITLLDQAIEEYPLQKKEHSPEFLREISH
CCHHHHHHEEEECEEEECCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LRARTKTFQAIFRIRSTAAFAIHKFFQENNYVYVTTPIITSNDAEGAGEQFVVTVNEDKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEECCCCCCCCCEEEEEEECCCC
YANDFFGKKASLTVSGQLNGEAFAQAFKNIYTFGPTFRAENSHTTKHASEFMIEPEVAFA
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHEECCCEEEE
DINDNIQLMQDMLKSVVGYVLEKNMTELEFLQEQLEPGLIDKITGIVNVEFKVNTYEEVL
ECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCEEEEEEEECCHHHHH
KTLQDAIDKGHKFEENNIHFGLDLGTEHERFICEEVNKCPTFVINYPKDIKSFYMKQNDD
HHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCC
GKTVAAVDLLVPGIGELCGGSEREANLDKILERCEFYGINPEELDYIGLRKYGFYKSAGF
CCEEEEEEHHHCCCHHHCCCCCCCCCHHHHHHHHHHCCCCHHHCCEEECHHCCCCCCCCC
GLGFERLIMYITGASNIRDVIPFPRTPKTLLY
CCCHHHHEEEEECCCCCHHCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA