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The map label for this gene is efp [H]

Identifier: 50365225

GI number: 50365225

Start: 476265

End: 476822

Strand: Reverse

Name: efp [H]

Synonym: Mfl407

Alternate gene names: 50365225

Gene position: 476822-476265 (Counterclockwise)

Preceding gene: 50365226

Following gene: 50365224

Centisome position: 60.11

GC content: 30.29

Gene sequence:

>558_bases
ATGTCAGTAAATGATTTACGTCCTGGAACAACATTTATATACGAAGGTAATTTATTTGTTGTTATTGAACAGTCTTTCTC
AAAAACAGGAAGACAACAAGGAAAAGTTAGTGTAAAAGCTAAAAACTTAAGAACTGGATCAAGAGTTGAAATAACTTTCA
CTGGTGGAGAAAAAGTTGAAAAAGCAATGATTGAAAGAAAAGATATGCAATATTTATACAATGATGGTACAGATGCATAC
TTAATGGATACAGATACTTATGAACAAATTCAAATACCAATGACTAGATTAGAATGAGAAAGTAAATTCTTAACAGATGG
ATTAATGATTAAAATGACTGAATATGATGGAGAAGTTTTAGGGATTTCTTTACCAGATAAAGTTGAATTAGAAGTTACTG
AAGCTGAAGCTGCAGTTAAAGGTGATACAACAAGTGGAGCATTAAAAAAAGCTGTTGTTGAAACTGGATTAGATATTATG
GTTCCATTATTTGTTAATGTAGGAACAAAAGTTATTATTTCTACAACAGATGGAAAATACAGCGGTAGAGCTCAATAA

Upstream 100 bases:

>100_bases
TCAAAAACAAAACTAAATGAAAAACTTTCAAACTTTTAGGTTAAATGCTATAATTTACTATGATTAAAATCAAAATCTTA
AAAAGAAAGAAGGAAAACAA

Downstream 100 bases:

>100_bases
TAATAAAAATAAGAAATAGAGGTGTAAGAATATGTATATTTCAATAGAAAGAAATAATCGTGGAGCATTAGAGATTGAAG
TTAATGCTTTAAATAAGTTA

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSVNDLRPGTTFIYEGNLFVVIEQSFSKTGRQQGKVSVKAKNLRTGSRVEITFTGGEKVEKAMIERKDMQYLYNDGTDAY
LMDTDTYEQIQIPMTRLEWESKFLTDGLMIKMTEYDGEVLGISLPDKVELEVTEAEAAVKGDTTSGALKKAVVETGLDIM
VPLFVNVGTKVIISTTDGKYSGRAQ

Sequences:

>Translated_185_residues
MSVNDLRPGTTFIYEGNLFVVIEQSFSKTGRQQGKVSVKAKNLRTGSRVEITFTGGEKVEKAMIERKDMQYLYNDGTDAY
LMDTDTYEQIQIPMTRLE*ESKFLTDGLMIKMTEYDGEVLGISLPDKVELEVTEAEAAVKGDTTSGALKKAVVETGLDIM
VPLFVNVGTKVIISTTDGKYSGRAQ
>Mature_184_residues
SVNDLRPGTTFIYEGNLFVVIEQSFSKTGRQQGKVSVKAKNLRTGSRVEITFTGGEKVEKAMIERKDMQYLYNDGTDAYL
MDTDTYEQIQIPMTRLE*ESKFLTDGLMIKMTEYDGEVLGISLPDKVELEVTEAEAAVKGDTTSGALKKAVVETGLDIMV
PLFVNVGTKVIISTTDGKYSGRAQ

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=32.967032967033, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI87082061, Length=185, Percent_Identity=30.8108108108108, Blast_Score=87, Evalue=7e-19,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20309; Mature: 20178

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNDLRPGTTFIYEGNLFVVIEQSFSKTGRQQGKVSVKAKNLRTGSRVEITFTGGEKVE
CCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCHHHH
KAMIERKDMQYLYNDGTDAYLMDTDTYEQIQIPMTRLEESKFLTDGLMIKMTEYDGEVLG
HHHHHHHCCCEEECCCCCEEEEECCCCCEEECCHHHHCCCCEECCCEEEEEEECCCEEEE
ISLPDKVELEVTEAEAAVKGDTTSGALKKAVVETGLDIMVPLFVNVGTKVIISTTDGKYS
EECCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCCCEEEEHEECCCCEEEEEECCCCCC
GRAQ
CCCC
>Mature Secondary Structure 
SVNDLRPGTTFIYEGNLFVVIEQSFSKTGRQQGKVSVKAKNLRTGSRVEITFTGGEKVE
CCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCHHHH
KAMIERKDMQYLYNDGTDAYLMDTDTYEQIQIPMTRLEESKFLTDGLMIKMTEYDGEVLG
HHHHHHHCCCEEECCCCCEEEEECCCCCEEECCHHHHCCCCEECCCEEEEEEECCCEEEE
ISLPDKVELEVTEAEAAVKGDTTSGALKKAVVETGLDIMVPLFVNVGTKVIISTTDGKYS
EECCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCCCEEEEHEECCCCEEEEEECCCCCC
GRAQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA