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The map label for this gene is dnaJ [H]

Identifier: 50365115

GI number: 50365115

Start: 344834

End: 345490

Strand: Direct

Name: dnaJ [H]

Synonym: Mfl299

Alternate gene names: 50365115

Gene position: 344834-345490 (Clockwise)

Preceding gene: 50365114

Following gene: 50365116

Centisome position: 43.47

GC content: 21.46

Gene sequence:

>657_bases
ATGTTAAAAGATAAGACTAATTTTATTAATAAATTAAAAATACAAGAGCAACTTAAAGTAGAGTTGCTTTTTCTTTATGA
ACGCTTTTCAAATAAAACTATTAATTTAATTAATAAGTTATCATTTGAAATACAAAATATCAAAAACAATATTAATCAAT
TCACGGATACTGATTTTTCATCAAATTTATATAACGAATTTAAACTAAAAGTTTTAATGAATCAAGATATTATTGAAAAC
AAAATAGAATTAATTGATGAAAGCTTCAAAGAAATTGATTTAAAAAAGCTTGAACAGTTAATGAATGAAATCATTTACAA
ATTAAATGAAAATTACATTTTAACTATTAAAAAATGAAAACAATTTATATTAAACAAATATGAAATTGATTTTGAATCAA
TTGAAATCAATTTTTCTGAAAACAAAAATAAGTTTGAAGACTTTTCACGTAAAAATATATTAGGCTCTAATTCAAACGTT
GACTTCTGACCTTATGAAATACTAGGAATTAGTTTAAATGCTTCAGACATGCAAATAAAACAAGCTTATAAAGCATTAGC
TAAGAAGTATCATCCAGATAATAACAAAGACCCTGAAGCAGAAGAAATGATGAAATTGATAAATAAAGCATATAATATAT
TAAGAGGAAAAGAATAA

Upstream 100 bases:

>100_bases
TTTGTTTATTGTTGTGATAAAAAACTTGGAACATATATATCAAATAAACTAAATGAATTAATTAAATAAAGTAGTAAAAT
TAATAATAAGAGGTTTTTAA

Downstream 100 bases:

>100_bases
TGAAAAGTACAATAAAAAAAATATTAAAATTTAGTCTATTATTAATTATTATTTGATCAATCTGAATAGTAATTTTTCTT
TTTTCGATTTTAATTGAAAT

Product: heat shock protein chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLKDKTNFINKLKIQEQLKVELLFLYERFSNKTINLINKLSFEIQNIKNNINQFTDTDFSSNLYNEFKLKVLMNQDIIEN
KIELIDESFKEIDLKKLEQLMNEIIYKLNENYILTIKKWKQFILNKYEIDFESIEINFSENKNKFEDFSRKNILGSNSNV
DFWPYEILGISLNASDMQIKQAYKALAKKYHPDNNKDPEAEEMMKLINKAYNILRGKE

Sequences:

>Translated_218_residues
MLKDKTNFINKLKIQEQLKVELLFLYERFSNKTINLINKLSFEIQNIKNNINQFTDTDFSSNLYNEFKLKVLMNQDIIEN
KIELIDESFKEIDLKKLEQLMNEIIYKLNENYILTIKK*KQFILNKYEIDFESIEINFSENKNKFEDFSRKNILGSNSNV
DF*PYEILGISLNASDMQIKQAYKALAKKYHPDNNKDPEAEEMMKLINKAYNILRGKE
>Mature_218_residues
MLKDKTNFINKLKIQEQLKVELLFLYERFSNKTINLINKLSFEIQNIKNNINQFTDTDFSSNLYNEFKLKVLMNQDIIEN
KIELIDESFKEIDLKKLEQLMNEIIYKLNENYILTIKK*KQFILNKYEIDFESIEINFSENKNKFEDFSRKNILGSNSNV
DF*PYEILGISLNASDMQIKQAYKALAKKYHPDNNKDPEAEEMMKLINKAYNILRGKE

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI56687498, Length=61, Percent_Identity=54.0983606557377, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 25714; Mature: 25714

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDKTNFINKLKIQEQLKVELLFLYERFSNKTINLINKLSFEIQNIKNNINQFTDTDFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SNLYNEFKLKVLMNQDIIENKIELIDESFKEIDLKKLEQLMNEIIYKLNENYILTIKKKQ
HHHHHHHHEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECHH
FILNKYEIDFESIEINFSENKNKFEDFSRKNILGSNSNVDFPYEILGISLNASDMQIKQA
HHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YKALAKKYHPDNNKDPEAEEMMKLINKAYNILRGKE
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKDKTNFINKLKIQEQLKVELLFLYERFSNKTINLINKLSFEIQNIKNNINQFTDTDFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SNLYNEFKLKVLMNQDIIENKIELIDESFKEIDLKKLEQLMNEIIYKLNENYILTIKKKQ
HHHHHHHHEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECHH
FILNKYEIDFESIEINFSENKNKFEDFSRKNILGSNSNVDFPYEILGISLNASDMQIKQA
HHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YKALAKKYHPDNNKDPEAEEMMKLINKAYNILRGKE
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA