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The map label for this gene is rpe [H]

Identifier: 50365039

GI number: 50365039

Start: 249208

End: 249879

Strand: Direct

Name: rpe [H]

Synonym: Mfl223

Alternate gene names: 50365039

Gene position: 249208-249879 (Clockwise)

Preceding gene: 50365038

Following gene: 50365040

Centisome position: 31.42

GC content: 25.15

Gene sequence:

>672_bases
ATGCAAAAAATAACAATAGCTCCTAGTTTTTTATCAGCTAATTTTGCAGATTTAAAAAATGAAATAAAAAGATGTAAAGA
AGCTAACATTGAATGAATACATTATGATGTTATGGATTATGATTTTGTTCCTAATTTAACATTTGGATCAAAAGTTTTAA
AAGATATCGTTAATTCAAGCGACTTTAAAATTGATATACACTTTATGGTTAAAGTAAAAACAAAAAGGTTTGAAGACTTT
TTTTCAGAATACATTAAATGTAAACCTACTATGATGACAATGCATGTTGAATCAATGTCTAAAAAAGAAATAAATATGTT
TTATAACATATGTAAAACAAATAATATAATGTTTAGTTTAGCTGTTTCACCAAAGACAAATATAAAAGTTTTAAATAAAT
GAATAGATAAATTAGAAAACATCTTGATAATGAGTGTAGAGCCAGGATTTGGTGGTCAATCATTCATTCCCGAAGTTTTA
GAAAAAGTAAAACATTTAGCTGAATTGAAAAAAACAAATGGATACACTTATTCTATTGAAATTGATGGTGGAATTAATGA
TGAAACTAGTAAAAAAGCTATCGATGCAGGTGTAGAAATGATAGTTGCAGGAAGCTATTTATTTGAAAGCAAAAACTTTT
TAGAGAAAGTTGAATCTTTAAAACATGATTAA

Upstream 100 bases:

>100_bases
GTGTAAAAGAAGCTGTTGAACAAAATAAAATACCAGTTTTTATATACGAAGATTATAAAAAGATATATGAAGAAATATCA
AACAGAAAGGTAAAATACTA

Downstream 100 bases:

>100_bases
AAATATTATTATTGTTGCAGCTAAAACAAACATAAATTTAAATATATTTAATAATGATGAATCTTTTATTATTGGTGTAG
AGCGTGGTTGCTTAGATTTA

Product: pentose-5-phosphate-3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MQKITIAPSFLSANFADLKNEIKRCKEANIEWIHYDVMDYDFVPNLTFGSKVLKDIVNSSDFKIDIHFMVKVKTKRFEDF
FSEYIKCKPTMMTMHVESMSKKEINMFYNICKTNNIMFSLAVSPKTNIKVLNKWIDKLENILIMSVEPGFGGQSFIPEVL
EKVKHLAELKKTNGYTYSIEIDGGINDETSKKAIDAGVEMIVAGSYLFESKNFLEKVESLKHD

Sequences:

>Translated_223_residues
MQKITIAPSFLSANFADLKNEIKRCKEANIE*IHYDVMDYDFVPNLTFGSKVLKDIVNSSDFKIDIHFMVKVKTKRFEDF
FSEYIKCKPTMMTMHVESMSKKEINMFYNICKTNNIMFSLAVSPKTNIKVLNK*IDKLENILIMSVEPGFGGQSFIPEVL
EKVKHLAELKKTNGYTYSIEIDGGINDETSKKAIDAGVEMIVAGSYLFESKNFLEKVESLKHD
>Mature_223_residues
MQKITIAPSFLSANFADLKNEIKRCKEANIE*IHYDVMDYDFVPNLTFGSKVLKDIVNSSDFKIDIHFMVKVKTKRFEDF
FSEYIKCKPTMMTMHVESMSKKEINMFYNICKTNNIMFSLAVSPKTNIKVLNK*IDKLENILIMSVEPGFGGQSFIPEVL
EKVKHLAELKKTNGYTYSIEIDGGINDETSKKAIDAGVEMIVAGSYLFESKNFLEKVESLKHD

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=209, Percent_Identity=32.0574162679426, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI219879828, Length=209, Percent_Identity=30.1435406698565, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI24307923, Length=97, Percent_Identity=36.0824742268041, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789788, Length=222, Percent_Identity=34.6846846846847, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790523, Length=199, Percent_Identity=28.643216080402, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=24.1545893719807, Blast_Score=70, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17552948, Length=210, Percent_Identity=30.952380952381, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322341, Length=226, Percent_Identity=33.1858407079646, Blast_Score=109, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24586301, Length=217, Percent_Identity=30.8755760368664, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 25248; Mature: 25248

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKITIAPSFLSANFADLKNEIKRCKEANIEIHYDVMDYDFVPNLTFGSKVLKDIVNSSD
CCEEEECHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCC
FKIDIHFMVKVKTKRFEDFFSEYIKCKPTMMTMHVESMSKKEINMFYNICKTNNIMFSLA
EEEEEEEEEEEEHHHHHHHHHHHHCCCCEEEEEEHHHHCHHHHHHHHHHHCCCCEEEEEE
VSPKTNIKVLNKIDKLENILIMSVEPGFGGQSFIPEVLEKVKHLAELKKTNGYTYSIEID
ECCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
GGINDETSKKAIDAGVEMIVAGSYLFESKNFLEKVESLKHD
CCCCCCHHHHHHHHCHHEEEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKITIAPSFLSANFADLKNEIKRCKEANIEIHYDVMDYDFVPNLTFGSKVLKDIVNSSD
CCEEEECHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCC
FKIDIHFMVKVKTKRFEDFFSEYIKCKPTMMTMHVESMSKKEINMFYNICKTNNIMFSLA
EEEEEEEEEEEEHHHHHHHHHHHHCCCCEEEEEEHHHHCHHHHHHHHHHHCCCCEEEEEE
VSPKTNIKVLNKIDKLENILIMSVEPGFGGQSFIPEVLEKVKHLAELKKTNGYTYSIEID
ECCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
GGINDETSKKAIDAGVEMIVAGSYLFESKNFLEKVESLKHD
CCCCCCHHHHHHHHCHHEEEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]