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The map label for this gene is engA [H]

Identifier: 50365015

GI number: 50365015

Start: 225425

End: 226732

Strand: Direct

Name: engA [H]

Synonym: Mfl199

Alternate gene names: 50365015

Gene position: 225425-226732 (Clockwise)

Preceding gene: 50365014

Following gene: 50365016

Centisome position: 28.42

GC content: 28.29

Gene sequence:

>1308_bases
ATGAAAAAAGGTATAGTCGCTATAGTAGGTAGACCTAATGTTGGTAAATCATCTTTATTTAATAGAATAATTAGAGAAAA
AAAATCTATTGTTGAAGATACACCTGGTGTAACAAGAGATAGAATTTATGGAACAGCAGAATGATTAACAAGAGAATTCA
TAGTTATTGATACTGGTGGTATAACTCTTGAGGATCAACCGTTTGCAAAAGAAATTAAAGTGCAGGCAGAAATAGCAATG
GAAGAAGCTGATGTTATTGTATTTTTATTAAATCATCAAGAAGGTTTATCTGATGAAGATAAAATGATAGCTAAAATTCT
TTATAAGACAAAAAAACCAATTGTTCTAGCAGTAAACAAATATGATAAAAAAACTTCTGACTTTGATCAATATGAATATA
TGAGTTTAGGATTTGGAGAACCTATTTTAATTAGTGCAACTCACGGTATTGGAACTGGGGATTTATTAGATGACATAATT
CATCAAATGCCTTCTCATGAAGAAATTAATAAAGACAATAGAACTAGAGTATCAATTATTGGTAGACCTAATGTTGGTAA
ATCGTCTCTTGTTAATTCACTAATTGGTGAGGAAAGAATGATTGTAAGTGATATCCCAGGAACAACACTTGATGCTGTAG
ATTCAGTTGTTAAAGTTAACAACATTGAATATACATTAATAGATACAGCAGGAATACGGAAGAAATCAAAGATTTTTCAA
AATGTTGAAAAATATAGTTATTTAAGATCTTTGACAACAATTAATGGTAGTGATGTAGTTTTACTTATGTTAGATGCATC
TGTACCAATAAGCGATTTAGATACAAATATTGGTGGTTTAGCTTTTGAAGAAAAAAAACCTATCATAATAATTGCTAATA
AATGAGATTTAGTAGAAAACAAAGAAAAAGAAATATTAAAAAAAGAAGATGAAATAAGAGCTTACTTTAAATATTTAGCT
TATGCTAAAATTCTGTTTGTTTCTGCACATGATAAAACAAGAATTACTAAAATATTTACAGCAGTTGAAGATATTAGAAC
TGCACTTGATAAAAAAATTAAAACTTCTGTTTTCAATGAAGTTTTAAATAAAGCGCAATTAATAAATCCAGCACCAAATT
TCAATGGTGGAAGACTTAAAATTTATTACGGAGCACAAGTTGAAGCTTATCTTCCAACATTTGTTCTTTTTGTGAACAAT
CCAGATTATGTTCACTTTTCATATAAAAGGTTTTTAGAGAATCAAATAAGACTTCAATTTGGTTTTGAAGGTGTACCAAT
GTCAATTATTTTCAGGGAAAGGAAATAA

Upstream 100 bases:

>100_bases
AAGCAGAAGATGCTTGATTAATTGATAATTCAAATATTCCAATCCAAGATGTTGTTAATATGGTTATTGATAAAATAAAA
GAATTGGAAGGTAATTAATT

Downstream 100 bases:

>100_bases
GCACTATGAGTAAAAAAAATATAACAATTATAGGAACTGGAGCTTACGGAACAGCATTAGCGAATGTATTAGCAGATAAT
GATAACAATGTTATTATGTA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKKGIVAIVGRPNVGKSSLFNRIIREKKSIVEDTPGVTRDRIYGTAEWLTREFIVIDTGGITLEDQPFAKEIKVQAEIAM
EEADVIVFLLNHQEGLSDEDKMIAKILYKTKKPIVLAVNKYDKKTSDFDQYEYMSLGFGEPILISATHGIGTGDLLDDII
HQMPSHEEINKDNRTRVSIIGRPNVGKSSLVNSLIGEERMIVSDIPGTTLDAVDSVVKVNNIEYTLIDTAGIRKKSKIFQ
NVEKYSYLRSLTTINGSDVVLLMLDASVPISDLDTNIGGLAFEEKKPIIIIANKWDLVENKEKEILKKEDEIRAYFKYLA
YAKILFVSAHDKTRITKIFTAVEDIRTALDKKIKTSVFNEVLNKAQLINPAPNFNGGRLKIYYGAQVEAYLPTFVLFVNN
PDYVHFSYKRFLENQIRLQFGFEGVPMSIIFRERK

Sequences:

>Translated_435_residues
MKKGIVAIVGRPNVGKSSLFNRIIREKKSIVEDTPGVTRDRIYGTAE*LTREFIVIDTGGITLEDQPFAKEIKVQAEIAM
EEADVIVFLLNHQEGLSDEDKMIAKILYKTKKPIVLAVNKYDKKTSDFDQYEYMSLGFGEPILISATHGIGTGDLLDDII
HQMPSHEEINKDNRTRVSIIGRPNVGKSSLVNSLIGEERMIVSDIPGTTLDAVDSVVKVNNIEYTLIDTAGIRKKSKIFQ
NVEKYSYLRSLTTINGSDVVLLMLDASVPISDLDTNIGGLAFEEKKPIIIIANK*DLVENKEKEILKKEDEIRAYFKYLA
YAKILFVSAHDKTRITKIFTAVEDIRTALDKKIKTSVFNEVLNKAQLINPAPNFNGGRLKIYYGAQVEAYLPTFVLFVNN
PDYVHFSYKRFLENQIRLQFGFEGVPMSIIFRERK
>Mature_435_residues
MKKGIVAIVGRPNVGKSSLFNRIIREKKSIVEDTPGVTRDRIYGTAE*LTREFIVIDTGGITLEDQPFAKEIKVQAEIAM
EEADVIVFLLNHQEGLSDEDKMIAKILYKTKKPIVLAVNKYDKKTSDFDQYEYMSLGFGEPILISATHGIGTGDLLDDII
HQMPSHEEINKDNRTRVSIIGRPNVGKSSLVNSLIGEERMIVSDIPGTTLDAVDSVVKVNNIEYTLIDTAGIRKKSKIFQ
NVEKYSYLRSLTTINGSDVVLLMLDASVPISDLDTNIGGLAFEEKKPIIIIANK*DLVENKEKEILKKEDEIRAYFKYLA
YAKILFVSAHDKTRITKIFTAVEDIRTALDKKIKTSVFNEVLNKAQLINPAPNFNGGRLKIYYGAQVEAYLPTFVLFVNN
PDYVHFSYKRFLENQIRLQFGFEGVPMSIIFRERK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=463, Percent_Identity=35.85313174946, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=41.9354838709677, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788919, Length=153, Percent_Identity=32.0261437908497, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=85, Percent_Identity=37.6470588235294, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=174, Percent_Identity=34.4827586206897, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48859; Mature: 48859

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGIVAIVGRPNVGKSSLFNRIIREKKSIVEDTPGVTRDRIYGTAELTREFIVIDTGGI
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEECCHHHCEEEEEEECCCE
TLEDQPFAKEIKVQAEIAMEEADVIVFLLNHQEGLSDEDKMIAKILYKTKKPIVLAVNKY
EECCCCCHHHHEEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECC
DKKTSDFDQYEYMSLGFGEPILISATHGIGTGDLLDDIIHQMPSHEEINKDNRTRVSIIG
CCCCCCCCHHHHEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
RPNVGKSSLVNSLIGEERMIVSDIPGTTLDAVDSVVKVNNIEYTLIDTAGIRKKSKIFQN
CCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHEECCEEEEEEECCCCCHHHHHHHH
VEKYSYLRSLTTINGSDVVLLMLDASVPISDLDTNIGGLAFEEKKPIIIIANKDLVENKE
HHHHHHHHHHHCCCCCCEEEEEEECCCCHHHCCCCCCCEEEECCCCEEEEECCHHHCCHH
KEILKKEDEIRAYFKYLAYAKILFVSAHDKTRITKIFTAVEDIRTALDKKIKTSVFNEVL
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKAQLINPAPNFNGGRLKIYYGAQVEAYLPTFVLFVNNPDYVHFSYKRFLENQIRLQFGF
HHHEECCCCCCCCCCEEEEEECCEEEEECCEEEEEECCCCEEEEHHHHHHCCCEEEEECC
EGVPMSIIFRERK
CCCCEEEEEECCC
>Mature Secondary Structure
MKKGIVAIVGRPNVGKSSLFNRIIREKKSIVEDTPGVTRDRIYGTAELTREFIVIDTGGI
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEECCHHHCEEEEEEECCCE
TLEDQPFAKEIKVQAEIAMEEADVIVFLLNHQEGLSDEDKMIAKILYKTKKPIVLAVNKY
EECCCCCHHHHEEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECC
DKKTSDFDQYEYMSLGFGEPILISATHGIGTGDLLDDIIHQMPSHEEINKDNRTRVSIIG
CCCCCCCCHHHHEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
RPNVGKSSLVNSLIGEERMIVSDIPGTTLDAVDSVVKVNNIEYTLIDTAGIRKKSKIFQN
CCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHEECCEEEEEEECCCCCHHHHHHHH
VEKYSYLRSLTTINGSDVVLLMLDASVPISDLDTNIGGLAFEEKKPIIIIANKDLVENKE
HHHHHHHHHHHCCCCCCEEEEEEECCCCHHHCCCCCCCEEEECCCCEEEEECCHHHCCHH
KEILKKEDEIRAYFKYLAYAKILFVSAHDKTRITKIFTAVEDIRTALDKKIKTSVFNEVL
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKAQLINPAPNFNGGRLKIYYGAQVEAYLPTFVLFVNNPDYVHFSYKRFLENQIRLQFGF
HHHEECCCCCCCCCCEEEEEECCEEEEECCEEEEEECCCCEEEEHHHHHHCCCEEEEECC
EGVPMSIIFRERK
CCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA