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The map label for this gene is adhR [H]

Identifier: 50364987

GI number: 50364987

Start: 200442

End: 200921

Strand: Direct

Name: adhR [H]

Synonym: Mfl171

Alternate gene names: 50364987

Gene position: 200442-200921 (Clockwise)

Preceding gene: 50364986

Following gene: 50364988

Centisome position: 25.27

GC content: 22.71

Gene sequence:

>480_bases
ATGAATAATTTAACAAATAGTGAAAGATTAAATGAAAATATAAAAGTAATTACAAAACAAAAATTAAGTATTAAAGAAAT
AGCAACTATATTTGATGTTTCAGAACAAACAATTAGATTTTATGATTCTAAAGGTTTATTACCATTTTTTGAAAGAGAAG
ATAATAATTACAGATATACAACAGTTGAAAATTTGCAATGATTTAAAATGGTTTTCTTGCTAAGATCAGCTGGAATGGAA
ATCAAGAATATAAAAGAATATATAAATTTATGTATGGAAGGTGATTCAACCGTTCCTCAAAGACTAAAGATAATCCAAGA
TCAAAAGAAAGATTTAGTTTCAAAAATTAAAGGCTTACAATCTGAACTTGAATTGCTAACAAGTAAAGAAAAACACTACA
AAAAAATTCTTGAAGAAAATATATTGGATGAATGAAATCCAGTTAATTTTGAAGAAATTATACAAAAAAAATTAAAATAA

Upstream 100 bases:

>100_bases
ATTTACAATCATCTATTTCATATGCAGGTGGTAAAACATTAAAAGCTATTAAAAAAGTAGACTACGTAATTTTAAAAACA
AGTAACTTTTAATTTTAAAA

Downstream 100 bases:

>100_bases
CATTTTTTGCTTGCCTTATAGTTACTATAATGTTTTACAATCAATTTATAATCATATAAAGGAGATTTTAAAATGAAAAA
TAAAGTATGATTTGTAACAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNNLTNSERLNENIKVITKQKLSIKEIATIFDVSEQTIRFYDSKGLLPFFEREDNNYRYTTVENLQWFKMVFLLRSAGME
IKNIKEYINLCMEGDSTVPQRLKIIQDQKKDLVSKIKGLQSELELLTSKEKHYKKILEENILDEWNPVNFEEIIQKKLK

Sequences:

>Translated_159_residues
MNNLTNSERLNENIKVITKQKLSIKEIATIFDVSEQTIRFYDSKGLLPFFEREDNNYRYTTVENLQ*FKMVFLLRSAGME
IKNIKEYINLCMEGDSTVPQRLKIIQDQKKDLVSKIKGLQSELELLTSKEKHYKKILEENILDE*NPVNFEEIIQKKLK
>Mature_159_residues
MNNLTNSERLNENIKVITKQKLSIKEIATIFDVSEQTIRFYDSKGLLPFFEREDNNYRYTTVENLQ*FKMVFLLRSAGME
IKNIKEYINLCMEGDSTVPQRLKIIQDQKKDLVSKIKGLQSELELLTSKEKHYKKILEENILDE*NPVNFEEIIQKKLK

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 18528; Mature: 18528

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLTNSERLNENIKVITKQKLSIKEIATIFDVSEQTIRFYDSKGLLPFFEREDNNYRYT
CCCCCCHHHHCCCHHHHHHCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEECCCCCEEEE
TVENLQFKMVFLLRSAGMEIKNIKEYINLCMEGDSTVPQRLKIIQDQKKDLVSKIKGLQS
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELELLTSKEKHYKKILEENILDENPVNFEEIIQKKLK
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNNLTNSERLNENIKVITKQKLSIKEIATIFDVSEQTIRFYDSKGLLPFFEREDNNYRYT
CCCCCCHHHHCCCHHHHHHCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEECCCCCEEEE
TVENLQFKMVFLLRSAGMEIKNIKEYINLCMEGDSTVPQRLKIIQDQKKDLVSKIKGLQS
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELELLTSKEKHYKKILEENILDENPVNFEEIIQKKLK
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]