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The map label for this gene is yfmM [H]

Identifier: 50364868

GI number: 50364868

Start: 66405

End: 67943

Strand: Reverse

Name: yfmM [H]

Synonym: Mfl053

Alternate gene names: 50364868

Gene position: 67943-66405 (Counterclockwise)

Preceding gene: 50364869

Following gene: 50364866

Centisome position: 8.57

GC content: 31.06

Gene sequence:

>1539_bases
ATGAGTTTAATATTATTAGAAAACATATCACATCAAAATGGTGGAAAAAAATTATATGAAGAATCAAGCATGCGAATCAA
CAAAGGTGAGCACGTTGCTCTTTTAGGTCCAAACGGGGCTGGTAAAACAACTTTACTAAATATTATTTCTCAAAAAATTG
TTCCAGATCACGGTTTGGTAGAATGACATCCAAAAGCAAAAATTGGATATCTTGATCAACACCAAGAAGTTGACATGAAT
ATTACTGGAGAAGAATATTTAAAAGATGCATTTAAATATCTTTTTGACATGGAAGCGCAAATTCATAAAATTTATGAAGA
CATGGCTACCGAATACAAAGAAGAAGAACTTGTTAAAGCTCTTGCTTTACAAGATGAATTAAATATTAAAGGGTTTGACA
GTATTGAGAAGCAAATAGGAAACTTGGTTGCTGGTCTTGGTATTGAACCAGATAATATTAAAAGACCCTTAGGATCACTT
TCTGGTGGTCAAAGAGGAAAAATATTATTAGCTAAACTACTTTTAAAAAACGATGACTTTATTTTACTTGATGAACCTAC
AAACTTTTTAGACGTTGAACAAGTTGAGTGATTAGTTAATTTCTTACAAAATTATGAAAATGCTTTTTTAGTTGTTTCTC
ATGATAGAGATTTTATAAATAGAATCGTTAATATAATATATGCAATTGAAAATCTTGAAATTGTTAGATATGTTGGTAAC
TATGACAAATACGTTGAACTTTCAGCGTTACGTGCTGAACAATATGATAGAGCTCGTGAAGCTCAACAAGGTCAGATATC
AAAACTTAAAGAATACATTGCTAAAAATGGTGCTAGAGCTTCAACTGCTCGCAGTGCTCAATCAAGACAAAAACAATTAG
AAAAAATTGACGTAATGGACGCTAGAAAAGAAAATGCAAAACCTAACATGCATTTTAAATATAGAAGACCAAGTTCAACT
GTTATAGTTAAAGCAGATAAACTTGAAATTGGTTATGATTTTGCTTTAACAAAACCATTAACTTTTGAACTTAGAGAAGG
TGAAAAATGTATCGTTAAAGGATATAACGGTATTGGTAAAACAACCTTCTTAAAAACTATTGCTGGAGAAATTGAGAAAA
TTGATGGTGAAGTTGAAATTGGACAAGGTGTTTTTACAAACTTTTTCCACCAGATTGATGACTTCGAAGAACACGAAACA
CCTGTTAGTTATTTACTAACAAGATATCCTCAAATGACACCTGGTGAAGTTAGAGCAAAGATTGGTATGTTTGGTATTAA
AAGTGAATTAATGATGAATAAAATGAAAGAACTTTCTGGGGGAGAACAAACAAAAGTTAGGTTAGCCGCTCTTAGTTTAG
AACCAAGTAGTTTACTTATTCTTGATGAGCCAACTAACCACATTGATGTTCTTGCAAAAGAATCTCTTTTAGATGCTATA
AAAGCATTTGAAGGTACAGTTTTAATTACAACCCACGATATTAACTTTGAAACTCAATGAGCTGATAAAGTTTTAGATTT
TGAAGATATCTTAGATTAA

Upstream 100 bases:

>100_bases
GGTATAACACTAAAAATAATAAAAATTTTAGATAAAGATTGATGACTTTATTATTATTTTTATTTTGATAAAATTAAAAA
GATTTATTTTAGGAGAACAT

Downstream 100 bases:

>100_bases
AAAAAGGAAACTTTGGGTTTCCTTTTTTTATATTAAATTAAAAGTTTTTAGCAGCTTTTAAAATTTGTTCTTTTACTTTT
TCTAAATTCTCAATTGGAGA

Product: multidrug ABC transporter ATP-binding component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSLILLENISHQNGGKKLYEESSMRINKGEHVALLGPNGAGKTTLLNIISQKIVPDHGLVEWHPKAKIGYLDQHQEVDMN
ITGEEYLKDAFKYLFDMEAQIHKIYEDMATEYKEEELVKALALQDELNIKGFDSIEKQIGNLVAGLGIEPDNIKRPLGSL
SGGQRGKILLAKLLLKNDDFILLDEPTNFLDVEQVEWLVNFLQNYENAFLVVSHDRDFINRIVNIIYAIENLEIVRYVGN
YDKYVELSALRAEQYDRAREAQQGQISKLKEYIAKNGARASTARSAQSRQKQLEKIDVMDARKENAKPNMHFKYRRPSST
VIVKADKLEIGYDFALTKPLTFELREGEKCIVKGYNGIGKTTFLKTIAGEIEKIDGEVEIGQGVFTNFFHQIDDFEEHET
PVSYLLTRYPQMTPGEVRAKIGMFGIKSELMMNKMKELSGGEQTKVRLAALSLEPSSLLILDEPTNHIDVLAKESLLDAI
KAFEGTVLITTHDINFETQWADKVLDFEDILD

Sequences:

>Translated_512_residues
MSLILLENISHQNGGKKLYEESSMRINKGEHVALLGPNGAGKTTLLNIISQKIVPDHGLVE*HPKAKIGYLDQHQEVDMN
ITGEEYLKDAFKYLFDMEAQIHKIYEDMATEYKEEELVKALALQDELNIKGFDSIEKQIGNLVAGLGIEPDNIKRPLGSL
SGGQRGKILLAKLLLKNDDFILLDEPTNFLDVEQVE*LVNFLQNYENAFLVVSHDRDFINRIVNIIYAIENLEIVRYVGN
YDKYVELSALRAEQYDRAREAQQGQISKLKEYIAKNGARASTARSAQSRQKQLEKIDVMDARKENAKPNMHFKYRRPSST
VIVKADKLEIGYDFALTKPLTFELREGEKCIVKGYNGIGKTTFLKTIAGEIEKIDGEVEIGQGVFTNFFHQIDDFEEHET
PVSYLLTRYPQMTPGEVRAKIGMFGIKSELMMNKMKELSGGEQTKVRLAALSLEPSSLLILDEPTNHIDVLAKESLLDAI
KAFEGTVLITTHDINFETQ*ADKVLDFEDILD
>Mature_511_residues
SLILLENISHQNGGKKLYEESSMRINKGEHVALLGPNGAGKTTLLNIISQKIVPDHGLVE*HPKAKIGYLDQHQEVDMNI
TGEEYLKDAFKYLFDMEAQIHKIYEDMATEYKEEELVKALALQDELNIKGFDSIEKQIGNLVAGLGIEPDNIKRPLGSLS
GGQRGKILLAKLLLKNDDFILLDEPTNFLDVEQVE*LVNFLQNYENAFLVVSHDRDFINRIVNIIYAIENLEIVRYVGNY
DKYVELSALRAEQYDRAREAQQGQISKLKEYIAKNGARASTARSAQSRQKQLEKIDVMDARKENAKPNMHFKYRRPSSTV
IVKADKLEIGYDFALTKPLTFELREGEKCIVKGYNGIGKTTFLKTIAGEIEKIDGEVEIGQGVFTNFFHQIDDFEEHETP
VSYLLTRYPQMTPGEVRAKIGMFGIKSELMMNKMKELSGGEQTKVRLAALSLEPSSLLILDEPTNHIDVLAKESLLDAIK
AFEGTVLITTHDINFETQ*ADKVLDFEDILD

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=503, Percent_Identity=28.4294234592445, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI27881506, Length=509, Percent_Identity=29.6660117878193, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI10947137, Length=509, Percent_Identity=29.6660117878193, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI69354671, Length=534, Percent_Identity=27.5280898876405, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI10947135, Length=534, Percent_Identity=27.5280898876405, Blast_Score=152, Evalue=1e-36,
Organism=Escherichia coli, GI1789751, Length=497, Percent_Identity=31.1871227364185, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1787041, Length=518, Percent_Identity=28.7644787644788, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1787182, Length=510, Percent_Identity=29.4117647058824, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI2367384, Length=502, Percent_Identity=27.4900398406374, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1788165, Length=224, Percent_Identity=29.0178571428571, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789593, Length=229, Percent_Identity=26.6375545851528, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786975, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17559834, Length=527, Percent_Identity=29.7912713472486, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17553372, Length=509, Percent_Identity=31.237721021611, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17555318, Length=513, Percent_Identity=27.2904483430799, Blast_Score=185, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6321121, Length=503, Percent_Identity=29.8210735586481, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320874, Length=511, Percent_Identity=29.1585127201566, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324314, Length=399, Percent_Identity=25.8145363408521, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323278, Length=399, Percent_Identity=23.3082706766917, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6325030, Length=438, Percent_Identity=23.972602739726, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24666836, Length=512, Percent_Identity=28.7109375, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24641342, Length=514, Percent_Identity=29.3774319066148, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24642252, Length=504, Percent_Identity=27.1825396825397, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI18859989, Length=504, Percent_Identity=27.1825396825397, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 57494; Mature: 57362

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLILLENISHQNGGKKLYEESSMRINKGEHVALLGPNGAGKTTLLNIISQKIVPDHGLV
CEEEEEECCCCCCCCHHHHHCCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
EHPKAKIGYLDQHQEVDMNITGEEYLKDAFKYLFDMEAQIHKIYEDMATEYKEEELVKAL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQDELNIKGFDSIEKQIGNLVAGLGIEPDNIKRPLGSLSGGQRGKILLAKLLLKNDDFI
HHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHHCCCCCCCHHHHHHHHHCCCCEE
LLDEPTNFLDVEQVELVNFLQNYENAFLVVSHDRDFINRIVNIIYAIENLEIVRYVGNYD
EEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCEEEEECCCCC
KYVELSALRAEQYDRAREAQQGQISKLKEYIAKNGARASTARSAQSRQKQLEKIDVMDAR
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KENAKPNMHFKYRRPSSTVIVKADKLEIGYDFALTKPLTFELREGEKCIVKGYNGIGKTT
HCCCCCCCEEEEECCCCEEEEEECCEEECCCEEECCCEEEEECCCCEEEEECCCCCCHHH
FLKTIAGEIEKIDGEVEIGQGVFTNFFHQIDDFEEHETPVSYLLTRYPQMTPGEVRAKIG
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCHHHHHHHH
MFGIKSELMMNKMKELSGGEQTKVRLAALSLEPSSLLILDEPTNHIDVLAKESLLDAIKA
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHH
FEGTVLITTHDINFETQADKVLDFEDILD
HCCEEEEEEECCCCCCCHHHCCCHHHHCC
>Mature Secondary Structure 
SLILLENISHQNGGKKLYEESSMRINKGEHVALLGPNGAGKTTLLNIISQKIVPDHGLV
EEEEEECCCCCCCCHHHHHCCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
EHPKAKIGYLDQHQEVDMNITGEEYLKDAFKYLFDMEAQIHKIYEDMATEYKEEELVKAL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQDELNIKGFDSIEKQIGNLVAGLGIEPDNIKRPLGSLSGGQRGKILLAKLLLKNDDFI
HHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHHCCCCCCCHHHHHHHHHCCCCEE
LLDEPTNFLDVEQVELVNFLQNYENAFLVVSHDRDFINRIVNIIYAIENLEIVRYVGNYD
EEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCEEEEECCCCC
KYVELSALRAEQYDRAREAQQGQISKLKEYIAKNGARASTARSAQSRQKQLEKIDVMDAR
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KENAKPNMHFKYRRPSSTVIVKADKLEIGYDFALTKPLTFELREGEKCIVKGYNGIGKTT
HCCCCCCCEEEEECCCCEEEEEECCEEECCCEEECCCEEEEECCCCEEEEECCCCCCHHH
FLKTIAGEIEKIDGEVEIGQGVFTNFFHQIDDFEEHETPVSYLLTRYPQMTPGEVRAKIG
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCHHHHHHHH
MFGIKSELMMNKMKELSGGEQTKVRLAALSLEPSSLLILDEPTNHIDVLAKESLLDAIKA
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHH
FEGTVLITTHDINFETQADKVLDFEDILD
HCCEEEEEEECCCCCCCHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]