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The map label for this gene is rhtC [H]

Identifier: 50085204

GI number: 50085204

Start: 2066652

End: 2067257

Strand: Reverse

Name: rhtC [H]

Synonym: ACIAD2083

Alternate gene names: 50085204

Gene position: 2067257-2066652 (Counterclockwise)

Preceding gene: 50085205

Following gene: 50085203

Centisome position: 57.45

GC content: 33.83

Gene sequence:

>606_bases
ATGGAACTATTTGTTGCGATTGCAGTTACTCATTTTATTGCCTTACTTTCGCCAGGCCCAGATTTTTTTCTGATTTTAAC
GACCTTGATCAAATCAGATAAGCATGCTGCCGTCAGAGTTTGTTGCGGAATAGCGTTTGGAAATGCAGCCATTATTGCTT
TCGTATTTATTGGATTACAACTACTGATCAGCAGCGACAAAAATGTGCTAATAGTCATCAAGTGGATCGGTATTTTATAT
TTACTCTATCTTTCTTGTTTATGCATCCGTTATGCCAAATCACCATTGAATTTGACACATGCAAATGACTCAAACATCTG
CAAAGGAAAATTGCATTTAATCAAAGGTGTTCAATCCAGTATTTTTAATCCAAAAAATATATTATTTTACAGTAGCTTGA
GTGTTTTAATTGCTGAAAAATTTAATTGGTATGAAAAACTTTCAATTTCAATCTGGATGGTGATTCTGGGTTGGAATCTG
TTTCTGGTTCGTATTCTGACATTCAATAAGTCAATGCAGTTTTTACAACGGAATTCTTGTAGATTATATTATGTCTCAGG
TGGGGCATTTTGCATCTTTTCAATACTTTTAATTGGTTATGCATGA

Upstream 100 bases:

>100_bases
CACCGAAAGACTATCAACAGCATTTTTCGCGCAATTTTATACAAGAGTAATCATTCAGGTTTTCTTATGCTCATGCTTTC
ATTTATAAGGGACGCCGAGC

Downstream 100 bases:

>100_bases
TTCTATTTTTTCAGGTTGAGGGTTTGTGCTCCAACAATCACAATCATTAGCAGCATGGTTAGAGAATATGAGAATGTATT
TTATTTAATAATCATTCTTT

Product: amino acid efflux protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MELFVAIAVTHFIALLSPGPDFFLILTTLIKSDKHAAVRVCCGIAFGNAAIIAFVFIGLQLLISSDKNVLIVIKWIGILY
LLYLSCLCIRYAKSPLNLTHANDSNICKGKLHLIKGVQSSIFNPKNILFYSSLSVLIAEKFNWYEKLSISIWMVILGWNL
FLVRILTFNKSMQFLQRNSCRLYYVSGGAFCIFSILLIGYA

Sequences:

>Translated_201_residues
MELFVAIAVTHFIALLSPGPDFFLILTTLIKSDKHAAVRVCCGIAFGNAAIIAFVFIGLQLLISSDKNVLIVIKWIGILY
LLYLSCLCIRYAKSPLNLTHANDSNICKGKLHLIKGVQSSIFNPKNILFYSSLSVLIAEKFNWYEKLSISIWMVILGWNL
FLVRILTFNKSMQFLQRNSCRLYYVSGGAFCIFSILLIGYA
>Mature_201_residues
MELFVAIAVTHFIALLSPGPDFFLILTTLIKSDKHAAVRVCCGIAFGNAAIIAFVFIGLQLLISSDKNVLIVIKWIGILY
LLYLSCLCIRYAKSPLNLTHANDSNICKGKLHLIKGVQSSIFNPKNILFYSSLSVLIAEKFNWYEKLSISIWMVILGWNL
FLVRILTFNKSMQFLQRNSCRLYYVSGGAFCIFSILLIGYA

Specific function: Conducts the efflux of threonine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=200, Percent_Identity=25.5, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22598; Mature: 22598

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELFVAIAVTHFIALLSPGPDFFLILTTLIKSDKHAAVRVCCGIAFGNAAIIAFVFIGLQ
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
LLISSDKNVLIVIKWIGILYLLYLSCLCIRYAKSPLNLTHANDSNICKGKLHLIKGVQSS
HHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHH
IFNPKNILFYSSLSVLIAEKFNWYEKLSISIWMVILGWNLFLVRILTFNKSMQFLQRNSC
CCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RLYYVSGGAFCIFSILLIGYA
EEEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MELFVAIAVTHFIALLSPGPDFFLILTTLIKSDKHAAVRVCCGIAFGNAAIIAFVFIGLQ
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
LLISSDKNVLIVIKWIGILYLLYLSCLCIRYAKSPLNLTHANDSNICKGKLHLIKGVQSS
HHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHH
IFNPKNILFYSSLSVLIAEKFNWYEKLSISIWMVILGWNLFLVRILTFNKSMQFLQRNSC
CCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RLYYVSGGAFCIFSILLIGYA
EEEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]