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The map label for this gene is yycF [H]

Identifier: 49188303

GI number: 49188303

Start: 5206935

End: 5207642

Strand: Reverse

Name: yycF [H]

Synonym: BAS5319

Alternate gene names: 49188303

Gene position: 5207642-5206935 (Counterclockwise)

Preceding gene: 49188304

Following gene: 49188302

Centisome position: 99.6

GC content: 39.55

Gene sequence:

>708_bases
ATGATGGGAAAGAAAATTTTAGTAGTTGATGATGAAAAGCCGATTGCAGATATTTTGAAGTTCAACCTAGAAAAAGAAGG
TTTTGAAATTGTAATGGCACACGATGGTGATGAAGCGATTGAAAAAGCGACTGAAGAACAGCCAGATATGGTTTTATTAG
ATATTATGCTACCAGGTAAGGATGGCTTAGAGGTTTGCCGTGAAATACGTAAAAGCTCAGAAATGCCGATTATTATGCTT
ACAGCGAAGGACTCTGAAATCGATAAAGTATTAGGTTTGGAGCTTGGGGCAGATGATTATGTAACGAAGCCATTTAGTAC
GAGGGAATTACTTGCTCGCGTGAAGGCGAATTTACGTCGCCATCAGCAAGGTGGTGCTGCAGAAAAAGAAGAAAATACGG
AAATGGTTATTGGGCCAATTGTTATCAATCCCAATGCGTATAGTGTAACGAAACGTGAGGAAAATATTGAGCTTACACAC
CGTGAATTTGAGCTGCTGCATTATTTAGCAAAACATTTAGGACAAGTTATGACACGCGAACATTTATTGCAAACAGTTTG
GGGTTATGACTACTTTGGAGATGTACGTACAGTGGATGTAACAGTACGTCGTCTACGTGAAAAAATTGAAGATAATCCAA
GTCATCCTACATTAATTGTCACTAGACGTGGAGTAGGGTATTACTTGCGTGACCCAGAGCAGGAATAG

Upstream 100 bases:

>100_bases
TTTAGCGAAAGCAAAGAAGTTAGGTGGGAAGCGAGCTTCCCGTAAAAGCCCGATTGGTGAGGGCTGATTAAAGTTTCACT
TTATAAGGAGGAAATAGACG

Downstream 100 bases:

>100_bases
TATATGAAGAAAGTCGGTTTTTTTCAATCTATTCATTTAAAATTTGTACTCATATATATGCTATTAATATTGATAGCTAT
GCAAGTTATTGGAGTATATT

Product: DNA-binding response regulator YycF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKATEEQPDMVLLDIMLPGKDGLEVCREIRKSSEMPIIML
TAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHQQGGAAEKEENTEMVIGPIVINPNAYSVTKREENIELTH
REFELLHYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE

Sequences:

>Translated_235_residues
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKATEEQPDMVLLDIMLPGKDGLEVCREIRKSSEMPIIML
TAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHQQGGAAEKEENTEMVIGPIVINPNAYSVTKREENIELTH
REFELLHYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE
>Mature_235_residues
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKATEEQPDMVLLDIMLPGKDGLEVCREIRKSSEMPIIML
TAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHQQGGAAEKEENTEMVIGPIVINPNAYSVTKREENIELTH
REFELLHYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=43.2314410480349, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=41.6666666666667, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=39.8230088495575, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=38.1165919282511, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=39.2857142857143, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=39.6551724137931, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=37.2881355932203, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=38.5964912280702, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=34.0807174887892, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=36.0869565217391, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=35.0649350649351, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.1858407079646, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=32.9059829059829, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=37.037037037037, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=32.7731092436975, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787487, Length=105, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26942; Mature: 26942

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKATEEQPDMVLLDIMLPGK
CCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCCCEEEEEEEECCC
DGLEVCREIRKSSEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRR
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHH
HQQGGAAEKEENTEMVIGPIVINPNAYSVTKREENIELTHREFELLHYLAKHLGQVMTRE
HHCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCC
>Mature Secondary Structure
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKATEEQPDMVLLDIMLPGK
CCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCCCEEEEEEEECCC
DGLEVCREIRKSSEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRR
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHH
HQQGGAAEKEENTEMVIGPIVINPNAYSVTKREENIELTHREFELLHYLAKHLGQVMTRE
HHCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]