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The map label for this gene is nsr [H]

Identifier: 49188246

GI number: 49188246

Start: 5144091

End: 5144762

Strand: Direct

Name: nsr [H]

Synonym: BAS5261

Alternate gene names: 49188246

Gene position: 5144091-5144762 (Clockwise)

Preceding gene: 49188244

Following gene: 49188251

Centisome position: 98.38

GC content: 31.1

Gene sequence:

>672_bases
ATGAAAGTCAGTAAAAATAGTGAAGAAATCTCTCATTACATACAAACTTACAACTTCCATACTCTTTTTTCTTTTGACAT
TTTACCGTATGCTGAACTACATTCCTTTCAGAAGAGAGAAAAAATATGTAATGAAGGGGTTGATGTTCCTTATCTTTATT
ACTTAATTTCTGGGAAAGCAAAAATATATATGAGTCACAAAAACGGAAAGGTCTCCTTAATTAACTTTATTCAAGCACCT
TCGTTCATTGGGGAATTAGGATTAATTGGCGTAGAATCCGTCACGAAAACGGTGGAAGTAATGGAAGATTGTATATGCTT
AGCGCTTCCTCTTAAAGATTGTCAGCATATTTTATTACAAGATGCTATTTTTCTACAGAAACTATGCAAATTTATCGGTG
AAAAAACAATTACCCGAACAGAAAGTTATGCCAAAAATAATAGTTATCCGTTCGAAAATCGATTAGCAGCGTTTATTCTA
TTAACAGAACAAAATAACAGTTATACAGAAAAACATACCGAGGCTTCGGAATATTTAAATGTTAGCTACCGTCACCTTTT
ATATGTATTAAATCAATTTTGCCAACAAAATTATTTAAAGAAAGATGGAAGAACCTATTACATACAAGATCGCAATCAAT
TAGAAAAACTTGCTGATGAGTTAAAAATATAA

Upstream 100 bases:

>100_bases
CTCACACTCTCTTTTCTACAAAAACAAATTTACGTAAATCGTAGCATTCTTTCTTGTAAAAATAATAGGAGATATCTCAT
ACTAAATATGAGGTGAAAAC

Downstream 100 bases:

>100_bases
AGAAACAGCATTAACATAAACGTTAATGCTGTTTCTTTGAGTGACGATTATAATTTCAATTAGAATTTATTTGCTACTTT
AGCTGCTTCTTCAAGACCAG

Product: DNA-binding transcriptional activator YeiL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKAKIYMSHKNGKVSLINFIQAP
SFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQDAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFIL
LTEQNNSYTEKHTEASEYLNVSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI

Sequences:

>Translated_223_residues
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKAKIYMSHKNGKVSLINFIQAP
SFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQDAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFIL
LTEQNNSYTEKHTEASEYLNVSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI
>Mature_223_residues
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKAKIYMSHKNGKVSLINFIQAP
SFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQDAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFIL
LTEQNNSYTEKHTEASEYLNVSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=203, Percent_Identity=45.320197044335, Blast_Score=181, Evalue=5e-47,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 26014; Mature: 26014

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKA
CCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCE
KIYMSHKNGKVSLINFIQAPSFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQ
EEEEECCCCCEEEHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFILLTEQNNSYTEKHTEASEYLN
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHCEEEEEEEECCCCCCHHHHHHHHHHHH
VSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKA
CCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCE
KIYMSHKNGKVSLINFIQAPSFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQ
EEEEECCCCCEEEHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFILLTEQNNSYTEKHTEASEYLN
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHCEEEEEEEECCCCCCHHHHHHHHHHHH
VSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]