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The map label for this gene is ung

Identifier: 49188235

GI number: 49188235

Start: 5132701

End: 5133378

Strand: Reverse

Name: ung

Synonym: BAS5250

Alternate gene names: 49188235

Gene position: 5133378-5132701 (Counterclockwise)

Preceding gene: 49188236

Following gene: 49188231

Centisome position: 98.18

GC content: 37.46

Gene sequence:

>678_bases
GTGAAACATGTTTTGAAAAATGATTGGGGGCCGTTATTGGCACCAGAATTTGAGAAAGAGTATTATCGCGAGCTGGATGT
TTTTTTGAAAGAAGAGTACAGTACACATGTTGTTTATCCAAAGATAGAAGATATCTTTAACGCTCTAGAGTATACAAGTT
ATGAAAATACAAAGGTCGTTATTTTAGGACAAGACCCATATCATGGGCCGAATCAAGCGCATGGTTTAAGCTTTTCTGTA
CAACCTGGTGTTAAAACGCCACCGTCATTGTTAAATATGTATAAAGAGCTTCGAGATGAATATGGGTATGACATTCCGAA
TAACGGTTATTTAGTGAAATGGGCAGAGCAAGGAGTATTACTACTAAATACTGTATTAACAGTTCGACAAGGCGAAGCAA
ATTCTCATAAGGGAAAAGGATGGGAGCATTTCACTGATCGTGTAATTGAGCTATTGAATGAACGTGAAAAACCAGTTATT
TTCATATTGTGGGGACGCCATGCACAGGCGAAGAAGAAGTTAATTACGAATCCAAATCATCAAATTATCGAATCTGTACA
TCCAAGTCCACTATCAGCAAGGCGAGGTTTCTTTGGGAGTAAGCCATACTCTAAAGTAAATACGATTTTAGCTAATATGG
GCGAGGGAGAAATTGATTGGGAAATTCCAAATTTATAA

Upstream 100 bases:

>100_bases
TTAATGAATTTAACTGTTTGGGGAATTGTATCTCTTATTATTTCATTTGTAGTATTTACAAAGCAGGATATGGTGAATTA
ATTAGACGGGAAGTGAAAGT

Downstream 100 bases:

>100_bases
ATAGAAAAGGTAGTTAACTGTCGTTAACTACCTTTTTATTATTGTTGTTCGTTCTTTAATTTTGCATCTAGTACAAATGT
ACCAAATGGGATAACTGATG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKHVLKNDWGPLLAPEFEKEYYRELDVFLKEEYSTHVVYPKIEDIFNALEYTSYENTKVVILGQDPYHGPNQAHGLSFSV
QPGVKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVLLLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVI
FILWGRHAQAKKKLITNPNHQIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEGEIDWEIPNL

Sequences:

>Translated_225_residues
MKHVLKNDWGPLLAPEFEKEYYRELDVFLKEEYSTHVVYPKIEDIFNALEYTSYENTKVVILGQDPYHGPNQAHGLSFSV
QPGVKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVLLLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVI
FILWGRHAQAKKKLITNPNHQIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEGEIDWEIPNL
>Mature_225_residues
MKHVLKNDWGPLLAPEFEKEYYRELDVFLKEEYSTHVVYPKIEDIFNALEYTSYENTKVVILGQDPYHGPNQAHGLSFSV
QPGVKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVLLLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVI
FILWGRHAQAKKKLITNPNHQIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEGEIDWEIPNL

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family

Homologues:

Organism=Homo sapiens, GI6224979, Length=215, Percent_Identity=49.7674418604651, Blast_Score=211, Evalue=3e-55,
Organism=Homo sapiens, GI19718751, Length=215, Percent_Identity=49.7674418604651, Blast_Score=211, Evalue=3e-55,
Organism=Escherichia coli, GI1788934, Length=214, Percent_Identity=53.2710280373832, Blast_Score=232, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17556304, Length=216, Percent_Identity=48.6111111111111, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323620, Length=239, Percent_Identity=46.4435146443515, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UNG_BACAA (C3P2F8)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002869611.1
- ProteinModelPortal:   C3P2F8
- SMR:   C3P2F8
- EnsemblBacteria:   EBBACT00000128005
- GeneID:   7849258
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_5675
- GeneTree:   EBGT00050000000847
- ProtClustDB:   PRK05254
- GO:   GO:0005737
- HAMAP:   MF_00148
- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122
- Gene3D:   G3DSA:3.40.470.10
- PANTHER:   PTHR11264
- TIGRFAMs:   TIGR00628

Pfam domain/function: PF03167 UDG; SSF52141 UDNA_glycsylseSF

EC number: =3.2.2.27

Molecular weight: Translated: 25919; Mature: 25919

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: ACT_SITE 65-65

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHVLKNDWGPLLAPEFEKEYYRELDVFLKEEYSTHVVYPKIEDIFNALEYTSYENTKVV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCEEE
ILGQDPYHGPNQAHGLSFSVQPGVKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVL
EECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEE
LLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVIFILWGRHAQAKKKLITNPNH
EEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCH
QIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEGEIDWEIPNL
HHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCC
>Mature Secondary Structure
MKHVLKNDWGPLLAPEFEKEYYRELDVFLKEEYSTHVVYPKIEDIFNALEYTSYENTKVV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCEEE
ILGQDPYHGPNQAHGLSFSVQPGVKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVL
EECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEE
LLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVIFILWGRHAQAKKKLITNPNH
EEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCH
QIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEGEIDWEIPNL
HHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA