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The map label for this gene is yfmP [H]

Identifier: 49188207

GI number: 49188207

Start: 5109650

End: 5110057

Strand: Reverse

Name: yfmP [H]

Synonym: BAS5221

Alternate gene names: 49188207

Gene position: 5110057-5109650 (Counterclockwise)

Preceding gene: 49188210

Following gene: 49188206

Centisome position: 97.73

GC content: 37.25

Gene sequence:

>408_bases
ATGTATAAGATTGATGAAGTTACAAAGCAAGTTGGTTTAACAAAACGTACACTTCGTTATTATGAGGAAATTGGTTTAAT
TCATCCCCCAGAACGTAGTGAGGGGAACATTCGCCTATATACAGATGAAGATATCGCAAGAATTAAAAGGATTGTAGAAG
CGAAAGAAGTACTAGGAATTACGCTACAAGAAATGCAGCATTTCTTATCGTTAAAAGAAAGAATGGAACAGAGAAGAAAT
AGCGAGAATCCTCGTGATCGTGAAGTGATTCAAGAAATTAAAGAGATGCTTGAAAAACAAGTGCAAACGCTAGACGAGAA
AATGGAGCAAATGCAGCGTGTGAAGGCCGAACTTGAGGATAGCTTACATCGTGCAGTGACATTTTTAGAGAATACAAAAG
GAGAGTAA

Upstream 100 bases:

>100_bases
AAAATACAATTTAATATGACAAACATTTACAAAAGTCTAACAGTTGCACAAAAGTTAACGTTAACGTAAAATGTAATAAT
TGAAGAAGGGAGGAATAAAC

Downstream 100 bases:

>100_bases
TCAAAATGGAGAGCAAACAAAAACTAGGGAGATTAATTACAGTGTTGGCTACTTTCCTTGCCTTTTCAGGTATAGGAGTA
GTCGACCCAATTTTGCCGAT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MYKIDEVTKQVGLTKRTLRYYEEIGLIHPPERSEGNIRLYTDEDIARIKRIVEAKEVLGITLQEMQHFLSLKERMEQRRN
SENPRDREVIQEIKEMLEKQVQTLDEKMEQMQRVKAELEDSLHRAVTFLENTKGE

Sequences:

>Translated_135_residues
MYKIDEVTKQVGLTKRTLRYYEEIGLIHPPERSEGNIRLYTDEDIARIKRIVEAKEVLGITLQEMQHFLSLKERMEQRRN
SENPRDREVIQEIKEMLEKQVQTLDEKMEQMQRVKAELEDSLHRAVTFLENTKGE
>Mature_135_residues
MYKIDEVTKQVGLTKRTLRYYEEIGLIHPPERSEGNIRLYTDEDIARIKRIVEAKEVLGITLQEMQHFLSLKERMEQRRN
SENPRDREVIQEIKEMLEKQVQTLDEKMEQMQRVKAELEDSLHRAVTFLENTKGE

Specific function: Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO, probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=126, Percent_Identity=30.1587301587302, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 16159; Mature: 16159

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKIDEVTKQVGLTKRTLRYYEEIGLIHPPERSEGNIRLYTDEDIARIKRIVEAKEVLGI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
TLQEMQHFLSLKERMEQRRNSENPRDREVIQEIKEMLEKQVQTLDEKMEQMQRVKAELED
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLHRAVTFLENTKGE
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MYKIDEVTKQVGLTKRTLRYYEEIGLIHPPERSEGNIRLYTDEDIARIKRIVEAKEVLGI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
TLQEMQHFLSLKERMEQRRNSENPRDREVIQEIKEMLEKQVQTLDEKMEQMQRVKAELED
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLHRAVTFLENTKGE
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]