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The map label for this gene is crr

Identifier: 49188155

GI number: 49188155

Start: 5050915

End: 5051412

Strand: Reverse

Name: crr

Synonym: BAS5169

Alternate gene names: 49188155

Gene position: 5051412-5050915 (Counterclockwise)

Preceding gene: 49188158

Following gene: 49188154

Centisome position: 96.61

GC content: 35.94

Gene sequence:

>498_bases
ATGTTTAAAAAATTATTCGGTCTTGGTTCAAAAACAAATGAAGAAACAATTGTAGCTCCATTAACTGGAGCAGTGAAAAA
TATTGAAGAAGTACCAGATCCAGTATTCGCTGGTCGTATGATGGGTGACGGTGTTGCAATCGATCCTACTGAAGGTGTAG
TTGTATCTCCAGTTGATGGTGAAATCGTACAATTATTCCACACGAAACATGCGATTGGAATTAAAGCGAAAAACGGTACA
GAAATTTTAATCCACGTTGGATTAGAAACTGTAAAAATGGAAGGTGAAGGTTTCGAAGCTCACGTTTCTGAAGGACAAGC
TGTAAAAGCTGGAGATAAATTAATCTCATTCGATTTAGAATTAATTCGTGAAAAAGCGAAAAGCACAATTACTCCAATCG
TTATTACAAACACAGATGCAGCTGAGTCTATTAAGACAACTGTAGGTGTAACTGCTACAAAAGGTTCAACAGAAGTAATG
AAAGTTACAATGAAATAA

Upstream 100 bases:

>100_bases
TTACAGTATAATATTCGAAGTATGAAGTCTTACGTTTATTCTGATCTTTAATAGAGATTGCCCTATAAACTTTTAGGTAA
ATTATAAGGAGGACTATCCT

Downstream 100 bases:

>100_bases
TTATTACATGAAGGGAGTCCGTTTCGTATGAAATGGATTCCTTATTTTGTTTTTGTAGTCTGTTCTTTATGTATGGTAAA
ATACTTTGGGCACTTGGAAA

Product: PTS system glucose-specific transporter subunit IIA

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Glc; EIII-Glc; PTS system glucose-specific EIIA component

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MFKKLFGLGSKTNEETIVAPLTGAVKNIEEVPDPVFAGRMMGDGVAIDPTEGVVVSPVDGEIVQLFHTKHAIGIKAKNGT
EILIHVGLETVKMEGEGFEAHVSEGQAVKAGDKLISFDLELIREKAKSTITPIVITNTDAAESIKTTVGVTATKGSTEVM
KVTMK

Sequences:

>Translated_165_residues
MFKKLFGLGSKTNEETIVAPLTGAVKNIEEVPDPVFAGRMMGDGVAIDPTEGVVVSPVDGEIVQLFHTKHAIGIKAKNGT
EILIHVGLETVKMEGEGFEAHVSEGQAVKAGDKLISFDLELIREKAKSTITPIVITNTDAAESIKTTVGVTATKGSTEVM
KVTMK
>Mature_165_residues
MFKKLFGLGSKTNEETIVAPLTGAVKNIEEVPDPVFAGRMMGDGVAIDPTEGVVVSPVDGEIVQLFHTKHAIGIKAKNGT
EILIHVGLETVKMEGEGFEAHVSEGQAVKAGDKLISFDLELIREKAKSTITPIVITNTDAAESIKTTVGVTATKGSTEVM
KVTMK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-1 domain

Homologues:

Organism=Escherichia coli, GI1788757, Length=166, Percent_Identity=46.3855421686747, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1790159, Length=123, Percent_Identity=49.5934959349593, Blast_Score=124, Evalue=2e-30,
Organism=Escherichia coli, GI1786894, Length=123, Percent_Identity=43.9024390243902, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): PTGA_BACAN (Q81JY0)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847720.1
- RefSeq:   YP_022231.1
- RefSeq:   YP_031408.1
- ProteinModelPortal:   Q81JY0
- SMR:   Q81JY0
- EnsemblBacteria:   EBBACT00000013352
- EnsemblBacteria:   EBBACT00000015942
- EnsemblBacteria:   EBBACT00000020713
- GeneID:   1085250
- GeneID:   2820053
- GeneID:   2851729
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_5563
- KEGG:   bar:GBAA_5563
- KEGG:   bat:BAS5169
- TIGR:   BA_5563
- TIGR:   GBAA_5563
- GeneTree:   EBGT00050000000034
- HOGENOM:   HBG517865
- OMA:   RRLISGQ
- ProtClustDB:   CLSK917671
- BioCyc:   BANT260799:BAS5169-MONOMER
- BioCyc:   BANT261594:GBAA5563-MONOMER
- GO:   GO:0005737
- GO:   GO:0016020
- InterPro:   IPR011055
- InterPro:   IPR001127
- TIGRFAMs:   TIGR00830

Pfam domain/function: PF00358 PTS_EIIA_1; SSF51261 Dup_hybrid_motif

EC number: 2.7.1.69

Molecular weight: Translated: 17475; Mature: 17475

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS51093 PTS_EIIA_TYPE_1; PS00371 PTS_EIIA_TYPE_1_HIS

Important sites: ACT_SITE 85-85

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLFGLGSKTNEETIVAPLTGAVKNIEEVPDPVFAGRMMGDGVAIDPTEGVVVSPVDG
CCCHHHCCCCCCCCCEEEEECCHHHHHHHHCCCCHHCCCCCCCCEEECCCCCEEEECCCC
EIVQLFHTKHAIGIKAKNGTEILIHVGLETVKMEGEGFEAHVSEGQAVKAGDKLISFDLE
HHEEEEECCEEEEEEECCCCEEEEEECCEEEEECCCCCEEECCCCCEEECCCEEEEHHHH
LIREKAKSTITPIVITNTDAAESIKTTVGVTATKGSTEVMKVTMK
HHHHHHHCCCCCEEEECCCCHHHHHHHEEEEECCCCCEEEEEEEC
>Mature Secondary Structure
MFKKLFGLGSKTNEETIVAPLTGAVKNIEEVPDPVFAGRMMGDGVAIDPTEGVVVSPVDG
CCCHHHCCCCCCCCCEEEEECCHHHHHHHHCCCCHHCCCCCCCCEEECCCCCEEEECCCC
EIVQLFHTKHAIGIKAKNGTEILIHVGLETVKMEGEGFEAHVSEGQAVKAGDKLISFDLE
HHEEEEECCEEEEEEECCCCEEEEEECCEEEEECCCCCEEECCCCCEEECCCEEEEHHHH
LIREKAKSTITPIVITNTDAAESIKTTVGVTATKGSTEVMKVTMK
HHHHHHHCCCCCEEEECCCCHHHHHHHEEEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629