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The map label for this gene is nuoN

Identifier: 49188126

GI number: 49188126

Start: 5023903

End: 5025423

Strand: Reverse

Name: nuoN

Synonym: BAS5140

Alternate gene names: 49188126

Gene position: 5025423-5023903 (Counterclockwise)

Preceding gene: 49188127

Following gene: 49188125

Centisome position: 96.11

GC content: 39.45

Gene sequence:

>1521_bases
ATGGATATGAATACGTTACTTAGCTTATCGTGGCATCTCATGGTGCCAGAATTCATCATTCTCGGGGCTGCCATCCTTCT
TTCCATATGTGATTTGTTTTTTAAGCTGAACCATAGATATGTAGCGCTTGGTGCAATCGCGGCGGTCGTATTAGCAATCG
TGTCACTAATTACGCTATATAGCGAACCAGCGGGAGATATTTTAAATGGATCGTTTGTGTTAGATGGATTTTCAAAAGGA
TTTAAAACGTTGTTGTTAGGCGGAGCCGCCCTCATCTTATGCACCGCAATGAGCGATGATAAGAAAAATCCAATTGAAGA
TAAGGGAGAGTATTATTACTTATTTTTAATGGCGCTTCTTGGGGCGATGTTTATGGCTTCTAGCGTTGATTTCGTTACAC
TTTTCGTCGGTTTAGAATTGCTTTCACTTTCTTCCTACATTTTAGTAGGAATACGAAAAAAGAACCGTGCATCAAATGAG
GCGGCCATGAAATATGTCATTAATGGAGGAATTGGAACGGCAATTACACTCTTTGGAATGAGTTACTTATACGGCATTAC
AGGGTCAACTAATATCGTGGATATGCAAAAAGTATTTGCCGGGGAACTGGCTAGTGGCATTCAGTTATTGCTAGCTCTCG
CATTCCTACTCTTACTCGTTGGGCTCTCATTCAAAATTGCGACAGTGCCGTTTCATATGTGGGCACCTGATGTGTATGAG
GGAGCGGCTACACCTGTTACTGCTTTTCTTGGAACAATTTCTAAAATGGCGGGTTTCTTACTCATTATTCGTTTGTTCCT
CATGGTTTTTGCAAGTGTATCAGTGCAAGGAGATATGCAATCTTTATACGGACGTATGAGCATATATATCGCTGTGCTAG
CTAGCATTACGATGATTATTGGAAATGTAGTCGCATTAAAGCAATATAACGTAAAACGCCTATTTGCTTATTCGGGAATC
GCCCATGCGGGATATTTACTCGTTCCGCTTGTCGCATTATCACCATTTACGATGGATAGTATGTGGTTTTACATGCTTGC
GTATATGCTTATGAATATAGGCGCGTTTGCAATTATCCACGGCTTAATCTTACAAAGCAATAAAGAAAATATTACCATTT
TCACTGGATTATATAAAAGGTCGCCATTTACAGCGATTGTGATGACGATTTTTATTTTATCGCTAGCGGGGATACCAGGA
ACAGCTGGTTTCATTGGGAAAATTAACATCTTTTTAGGGGCTCTTCATGTAGAGCCAGCTCATTACGTACTAGCTTCTAT
TATGATGGGGACGACAGTCATTTCATTCGTATATTATTTCCGTATTTTACAGCAAATGTTTTTCCGGACGGGAGAAGTAG
AAGAGAAAATTCGCTTGCCGCTCAATATAAAGATTGTGATGAGCTTTTGTGCAATTTCGATTGTAATACTAGGGATTGTG
CCGATGATTGGATACAATTTCTTTTATGAATATTTTCCATTAATGAAAGATTTCTTCTTCTTAGGGAACGTGGTACAATA
G

Upstream 100 bases:

>100_bases
ATCTTGCTACTTATCTTCTGCATTATTGCAATTGGCGTAATGCCAGAAATACTAGGGGATCCGCTTCAAAATACATTGAA
AACATTGGGGGTGAAGTAGG

Downstream 100 bases:

>100_bases
TGAAAATAAAAGGTGTGGAGTCGTTACTCTGCGCTTTTTATTTTTTGTGAACTACAATTGAAAATACATATAGGTATACG
TTTTTAAAGAGAAAAATTTC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYSEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFVTLFVGLELLSLSSYILVGIRKKNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSNKENITIFTGLYKRSPFTAIVMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ

Sequences:

>Translated_506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYSEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFVTLFVGLELLSLSSYILVGIRKKNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSNKENITIFTGLYKRSPFTAIVMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ
>Mature_506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYSEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFVTLFVGLELLSLSSYILVGIRKKNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSNKENITIFTGLYKRSPFTAIVMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831117, Length=319, Percent_Identity=24.4514106583072, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI145693160, Length=479, Percent_Identity=33.1941544885177, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1788831, Length=309, Percent_Identity=27.831715210356, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788613, Length=382, Percent_Identity=23.8219895287958, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788614, Length=305, Percent_Identity=27.8688524590164, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788827, Length=417, Percent_Identity=23.7410071942446, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788829, Length=386, Percent_Identity=22.279792746114, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_BACAN (Q81K10)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847690.1
- RefSeq:   YP_022200.1
- RefSeq:   YP_031379.1
- EnsemblBacteria:   EBBACT00000009286
- EnsemblBacteria:   EBBACT00000015325
- EnsemblBacteria:   EBBACT00000023273
- GeneID:   1085201
- GeneID:   2819061
- GeneID:   2852797
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_5532
- KEGG:   bar:GBAA_5532
- KEGG:   bat:BAS5140
- TIGR:   BA_5532
- TIGR:   GBAA_5532
- GeneTree:   EBGT00050000000597
- HOGENOM:   HBG747830
- OMA:   MDMNTLL
- ProtClustDB:   PRK05777
- BioCyc:   BANT260799:BAS5140-MONOMER
- BioCyc:   BANT261594:GBAA5532-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 55597; Mature: 55597

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17e53574)-; HASH(0x17b36bb4)-; HASH(0x17e3ea48)-; HASH(0x1832d8d8)-; HASH(0x17e0444c)-; HASH(0x17ce34ac)-; HASH(0x136c1cb4)-; HASH(0x17e45c20)-; HASH(0x17cef02c)-; HASH(0x17e897d8)-; HASH(0x17c5b758)-; HASH(0x17bb9864)-; HASH(0x18306270)-; HASH(0x17434fa0)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SEPAGDILNGSFVLDGFSKGFKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALL
CCCCCCCCCCCEEECCHHHHHHHHHHCCHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHH
GAMFMASSVDFVTLFVGLELLSLSSYILVGIRKKNRASNEAAMKYVINGGIGTAITLFGM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHEECCHHHHHHHHHH
SYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHC
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIH
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLILQSNKENITIFTGLYKRSPFTAIVMTIFILSLAGIPGTAGFIGKINIFLGALHVEPA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEECCHH
HYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
PMIGYNFFYEYFPLMKDFFFLGNVVQ
HHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SEPAGDILNGSFVLDGFSKGFKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALL
CCCCCCCCCCCEEECCHHHHHHHHHHCCHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHH
GAMFMASSVDFVTLFVGLELLSLSSYILVGIRKKNRASNEAAMKYVINGGIGTAITLFGM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHEECCHHHHHHHHHH
SYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHC
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIH
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLILQSNKENITIFTGLYKRSPFTAIVMTIFILSLAGIPGTAGFIGKINIFLGALHVEPA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEECCHH
HYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
PMIGYNFFYEYFPLMKDFFFLGNVVQ
HHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721629