Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 49188102

GI number: 49188102

Start: 4996441

End: 4996875

Strand: Reverse

Name: fabZ

Synonym: BAS5116

Alternate gene names: 49188102

Gene position: 4996875-4996441 (Counterclockwise)

Preceding gene: 49188104

Following gene: 49188101

Centisome position: 95.57

GC content: 37.47

Gene sequence:

>435_bases
ATGCTAGATATTCAACAAATTAAAGAAATAATTCCTCATCGCTATCCATTTCTACTAGTGGATAAAGTTTTAGAAGTAGA
AGAAGGAAAACGTGCTATTGGGATAAAGAATGTTACAGCTAATGAAGAATTTTTTAATGGACATTTTCCAGATTATCCTG
TAATGCCAGGTGTTTTAATTGTAGAGGCTTTAGCACAGGTTGGTGCTGTTGCTATGTTGAAAAAAGAGGAGAATCGTGGT
CGCTTAGCATTCTTCGCAGGCATTGATAATTGCCGTTTTAAAAGACAAGTCCGTCCAGGTGACCAACTACGTTTAGAAGT
TGAAATGACGCGTGTACGTGGAGCGATTGGAAAAGGAAAAGCAATTGCTACTGTAGATGGTGAAATTGCTTGTGAGACAG
AAATAACGTTCGCTCTTGGAGATAAAAAAGAATAG

Upstream 100 bases:

>100_bases
TCTTGAAATCCTTTTTTATAATGACAAATGAGATTTAAAATGGGATAATGATAGTATAACTTCTGGTGGTATGACCAATC
TTGTTTAAGGAGAGAAGTGT

Downstream 100 bases:

>100_bases
TAAACGTAAAATGTTTTTTATACAGATAGGTGGATACCAGGCTGAATTTGTAGCCTTGTGTCCACCTATTTTATTTGTAA
GTAGTAATATGTGATTTATT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLDIQQIKEIIPHRYPFLLVDKVLEVEEGKRAIGIKNVTANEEFFNGHFPDYPVMPGVLIVEALAQVGAVAMLKKEENRG
RLAFFAGIDNCRFKRQVRPGDQLRLEVEMTRVRGAIGKGKAIATVDGEIACETEITFALGDKKE

Sequences:

>Translated_144_residues
MLDIQQIKEIIPHRYPFLLVDKVLEVEEGKRAIGIKNVTANEEFFNGHFPDYPVMPGVLIVEALAQVGAVAMLKKEENRG
RLAFFAGIDNCRFKRQVRPGDQLRLEVEMTRVRGAIGKGKAIATVDGEIACETEITFALGDKKE
>Mature_144_residues
MLDIQQIKEIIPHRYPFLLVDKVLEVEEGKRAIGIKNVTANEEFFNGHFPDYPVMPGVLIVEALAQVGAVAMLKKEENRG
RLAFFAGIDNCRFKRQVRPGDQLRLEVEMTRVRGAIGKGKAIATVDGEIACETEITFALGDKKE

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=48.2014388489209, Blast_Score=139, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_BACAA (C3P1B5)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002869481.1
- ProteinModelPortal:   C3P1B5
- SMR:   C3P1B5
- EnsemblBacteria:   EBBACT00000128277
- GeneID:   7851923
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_5534
- GeneTree:   EBGT00050000002061
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16098; Mature: 16098

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIQQIKEIIPHRYPFLLVDKVLEVEEGKRAIGIKNVTANEEFFNGHFPDYPVMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCCCCCCCHHHH
VEALAQVGAVAMLKKEENRGRLAFFAGIDNCRFKRQVRPGDQLRLEVEMTRVRGAIGKGK
HHHHHHHHHHEEEEECCCCCCEEEEECCCCCEEEECCCCCCEEEEEEEEEHHHCCCCCCC
AIATVDGEIACETEITFALGDKKE
EEEEECCCEEEEEEEEEECCCCCC
>Mature Secondary Structure
MLDIQQIKEIIPHRYPFLLVDKVLEVEEGKRAIGIKNVTANEEFFNGHFPDYPVMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCCCCCCCHHHH
VEALAQVGAVAMLKKEENRGRLAFFAGIDNCRFKRQVRPGDQLRLEVEMTRVRGAIGKGK
HHHHHHHHHHEEEEECCCCCCEEEEECCCCCEEEECCCCCCEEEEEEEEEHHHCCCCCCC
AIATVDGEIACETEITFALGDKKE
EEEEECCCEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA