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The map label for this gene is pgtP [H]

Identifier: 49188095

GI number: 49188095

Start: 4987937

End: 4989271

Strand: Reverse

Name: pgtP [H]

Synonym: BAS5109

Alternate gene names: 49188095

Gene position: 4989271-4987937 (Counterclockwise)

Preceding gene: 49188096

Following gene: 49188092

Centisome position: 95.42

GC content: 37.45

Gene sequence:

>1335_bases
ATGTTTAAATGGCTCAAGCCAGCACCTGCAATTGAACGTTTACCAGCGGATATGATCGACCGTGTGTATCGATTACTACG
TATTCGCGTGTTAATCGGAATTTCAGTTGGATATGCTGCTTATTATTTAGTTCGTAGTAACTTTACGTTATCAAGTACGT
ACTTAGTACAAGAATATGGTTTTAGTACAGCTGAAATTGGTCTACTAGGTTCAGTAATGGCAATTGTTTATGGATTTAGT
AAGTTCTTTATGGGGAATTTATCAGATAAAGCTTTCGCCCAGCGCTTTATCGCAGTCGGTTTATTTTTATCAGGGCTTGT
AAATATTTGCTTCGGTTTTGCATCTTCATTTGGGATGATTGTTACATTACTTGTCGTTAACGGTATTGTACAAGGTATGG
GAGCACCACCTTGTAGTATTGTTATGACGAAATGGTTCTCGAAGAAAGAGCGCGGTACGAAAACAGGTATTTGGAATATT
TCACATAACGTTGGTGGAATGCTTGTACCACCACTTGTCGGAATTGGTGTAGGTATTTTTGGTGAAAATCATTGGCAAGG
CGGCGTGTTTATTTTCCCAGCGATTATCGCGATGGTAATTGCAGTTCTTGTTTGGATTAATGCGAAGGATACACCAGAAT
CAGAAGGTCTTCCTCCAATTGATGAGTATCGTAATGACTATGAAAATCTTGAAAAAGCAGACAACGCTAACAAGATGTCA
CCAAAAGAAATTTTAATGAAGTATGTAGTAAAAAATAAATTTGTATGGTTCTTATGTATTGCAAATGCATTTGTTTATTT
AATTCGCTTCGGTGTTATTAACTGGGTTCCACTTTATTTAACGACAGTTAAAGGCTTCTCAAAAAATGAAGCACATGCAG
CATACGCAATCTTTGAAGGTATGGCAATTCCAAGTTCATTAATCGTTGGTCTTTTAAGTGATAAATTATTTAAAGGAAAA
CGTATGCCACTATGTATTATTAGTATGGTCGGAGTTGTTATTGGTACGTTTGTATATTGGCAAGCAACTAGCATACTTGT
TGTAAGTATTGCAGTTTCTATTATCGGTTGTTTAATTTATGTACCACAGTTCTTAATCGGTTTAAGTGCGATGGAATTAG
TACCGAAATTTGCAGTAGGTACGACAGTTGGTATGTGTGGTCTATTCGGTTATGTAGGCGGAAGTCTTGTAGCAAACGCA
GCAATCGGTGTTATTGTTGATCGTTCTGGCTGGGATGGTTGTTTCATCTTACTATTAACAGGTGCCATTTTATCAACAAT
CTTCTTGTTCATCGTTCAACGTGGACATGAGAGCAAAGCTCCTAAAGCGGCGTAA

Upstream 100 bases:

>100_bases
CCGGTTAGAAGAACAAACCAAAATATATCAAATAGCGGAATAATCGAGATATGGAATAGACAACGTCTCTCTCAGAAGTG
AGAAAAGGAGACGAAAGAAT

Downstream 100 bases:

>100_bases
TATTTTGTTTGAAAAGCTATCCAATTGTGATTGGATAGCTTTTATATTAGGAAAAACAAACAGTATGTAAAATTGAAGTT
TAATATGTAAATAATTTTTG

Product: phosphoglycerate transporter family protein

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYGFSTAEIGLLGSVMAIVYGFS
KFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMIVTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNI
SHNVGGMLVPPLVGIGVGIFGENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYAIFEGMAIPSSLIVGLLSDKLFKGK
RMPLCIISMVGVVIGTFVYWQATSILVVSIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANA
AIGVIVDRSGWDGCFILLLTGAILSTIFLFIVQRGHESKAPKAA

Sequences:

>Translated_444_residues
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYGFSTAEIGLLGSVMAIVYGFS
KFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMIVTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNI
SHNVGGMLVPPLVGIGVGIFGENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYAIFEGMAIPSSLIVGLLSDKLFKGK
RMPLCIISMVGVVIGTFVYWQATSILVVSIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANA
AIGVIVDRSGWDGCFILLLTGAILSTIFLFIVQRGHESKAPKAA
>Mature_444_residues
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYGFSTAEIGLLGSVMAIVYGFS
KFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMIVTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNI
SHNVGGMLVPPLVGIGVGIFGENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYAIFEGMAIPSSLIVGLLSDKLFKGK
RMPLCIISMVGVVIGTFVYWQATSILVVSIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANA
AIGVIVDRSGWDGCFILLLTGAILSTIFLFIVQRGHESKAPKAA

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=429, Percent_Identity=24.4755244755245, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4503847, Length=429, Percent_Identity=24.4755244755245, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI256219483, Length=429, Percent_Identity=24.4755244755245, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI256219543, Length=451, Percent_Identity=23.7250554323725, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI38093649, Length=398, Percent_Identity=24.3718592964824, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI223717983, Length=398, Percent_Identity=24.3718592964824, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI256219564, Length=354, Percent_Identity=23.4463276836158, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI46361976, Length=425, Percent_Identity=24.2352941176471, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788573, Length=448, Percent_Identity=43.75, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI87082310, Length=433, Percent_Identity=33.7182448036951, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI2367259, Length=422, Percent_Identity=31.2796208530806, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI2367379, Length=361, Percent_Identity=24.6537396121884, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789515, Length=446, Percent_Identity=22.1973094170404, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082320, Length=278, Percent_Identity=24.8201438848921, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789152, Length=413, Percent_Identity=22.2760290556901, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564204, Length=375, Percent_Identity=25.8666666666667, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=370, Percent_Identity=25.9459459459459, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=379, Percent_Identity=23.2189973614776, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI133930953, Length=301, Percent_Identity=23.2558139534884, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656866, Length=492, Percent_Identity=20.9349593495935, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550478, Length=492, Percent_Identity=20.9349593495935, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656861, Length=492, Percent_Identity=20.9349593495935, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48415; Mature: 48415

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYG
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHC
FSTAEIGLLGSVMAIVYGFSKFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNISHNVGGMLVPPLVGIGVGIF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEHHHHHHCCHHCC
GENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
CCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYAIFEG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MAIPSSLIVGLLSDKLFKGKRMPLCIISMVGVVIGTFVYWQATSILVVSIAVSIIGCLIY
HCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANAAIGVIVDRSGWDGCFILLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHH
GAILSTIFLFIVQRGHESKAPKAA
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYG
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHC
FSTAEIGLLGSVMAIVYGFSKFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNISHNVGGMLVPPLVGIGVGIF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEHHHHHHCCHHCC
GENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
CCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYAIFEG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MAIPSSLIVGLLSDKLFKGKRMPLCIISMVGVVIGTFVYWQATSILVVSIAVSIIGCLIY
HCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANAAIGVIVDRSGWDGCFILLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHH
GAILSTIFLFIVQRGHESKAPKAA
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]