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The map label for this gene is lytF [H]

Identifier: 49188070

GI number: 49188070

Start: 4962959

End: 4963984

Strand: Direct

Name: lytF [H]

Synonym: BAS5084

Alternate gene names: 49188070

Gene position: 4962959-4963984 (Clockwise)

Preceding gene: 49188069

Following gene: 49188071

Centisome position: 94.92

GC content: 39.77

Gene sequence:

>1026_bases
GTGCAAGATTGGTTCAAAATCAATTATGCAGGTCAAACGGCTTACGTAAGTAAAGACTACGTAACAAAAGGCGGTTCTAG
CGATAACGTTACACAAGGAAACAACCAAAATAATAATCAAAACAATAATGTAACTGTTCAAACTGGTGGTACTTACGTTG
TTAACGCAACATCTCTACGCGTTCGTACAGGTCCTGCTACTTACCATAGCGTAATTGGTGGCGTATTAAATGGTACGACA
TTAAACGTAATTGGCTCTGAAGGTAGCTGGTTTAAAGTTAACTATCAAGGAAAAACAGGCTACGTTAGTAGCGAATTCAT
GAAATTCGTTAAAGGTGGCACTACTACTCCTGAGCAACCAAAACAACCTGAACAACCTAATCAAGGTGCAATTGGTGACT
ACTACATTAATGCTTCTGCCTTAAATGTACGTAGTGGTGAAGGTACAAATTATAGAATCATAGGCGCACTTCCACAAGGA
CAGAAGGTTCAAGTAATCTCTGAAAACTCTGGATGGAGCAAAATTAACTACAACGGTCAAACTGGTTATATCGGAACACG
TTACCTCTCTAAAACACCAGTTGGAGGCGCAGTAGATAATAATAAGCCTAACAACAACCAAAATAACAATCAAAACAATA
ACAACAATACAGGTAATAATAGCGGCAACAGTTCTTCCATACTTGCATATGCAAAAGGAATGCAAGGCGTACCATACGTT
TGGGGCGGAACTTCTGCTAACGGTGTGGACTGCAGTGGCTACATCTACCATGTATTTAAGAAATTTGGTCATAACATTAG
CCGTCAAAGTGTTGCGGGATATTGGGGTAGCCTACCACAAACTTCAAATCCACAACCAGGCGACTTAATTTATTTCCAAA
ACACTTATAAATCGGGTCCTTCTCACATGGGTATTTACCTTGGGGGCGGATCATTTATCCAAGCTGGAGATAAAGGTGTA
GCAATCGCTTCATTAAGCAATTCTTATTGGAGTAAGCACTTCTTAGGTTATACGAAAGCACCTTAA

Upstream 100 bases:

>100_bases
AGTAAATGTATCTTCCCTTCGTGTTCGTACAGGCCCTAGCACTTCTCACACAACTGTAGGTTCTGTTACAAAAGGACAAG
TAGTACAAGTTGTTGGCGAA

Downstream 100 bases:

>100_bases
GTTATATTTTTAGAGCCTTCTAGATTACTAGATGGCTCTTTTTATTATGTTTCACCTATATCCCTCAAAAAATAATGTAT
CTATTTTCCTATTTCATACA

Product: N-acetylmuramoyl-L-alanine amidase, C-terminus

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP49; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MQDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLRVRTGPATYHSVIGGVLNGTT
LNVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQPKQPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQG
QKVQVISENSGWSKINYNGQTGYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNTGNNSGNSSSILAYAKGMQGVPYV
WGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSNPQPGDLIYFQNTYKSGPSHMGIYLGGGSFIQAGDKGV
AIASLSNSYWSKHFLGYTKAP

Sequences:

>Translated_341_residues
MQDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLRVRTGPATYHSVIGGVLNGTT
LNVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQPKQPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQG
QKVQVISENSGWSKINYNGQTGYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNTGNNSGNSSSILAYAKGMQGVPYV
WGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSNPQPGDLIYFQNTYKSGPSHMGIYLGGGSFIQAGDKGV
AIASLSNSYWSKHFLGYTKAP
>Mature_341_residues
MQDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLRVRTGPATYHSVIGGVLNGTT
LNVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQPKQPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQG
QKVQVISENSGWSKINYNGQTGYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNTGNNSGNSSSILAYAKGMQGVPYV
WGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSNPQPGDLIYFQNTYKSGPSHMGIYLGGGSFIQAGDKGV
AIASLSNSYWSKHFLGYTKAP

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=145, Percent_Identity=29.6551724137931, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787944, Length=118, Percent_Identity=37.2881355932203, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788501, Length=128, Percent_Identity=32.03125, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: 3.5.1.28

Molecular weight: Translated: 36614; Mature: 36614

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLR
CCCEEEEEECCCEEEEEHHHEECCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEEEE
VRTGPATYHSVIGGVLNGTTLNVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQP
EEECCHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCC
KQPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQGQKVQVISENSGWSKINYNGQ
CCCCCCCCCCCEEEEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCC
TGYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNTGNNSGNSSSILAYAKGMQGVPYV
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEE
WGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSNPQPGDLIYFQNTYKSGP
ECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
SHMGIYLGGGSFIQAGDKGVAIASLSNSYWSKHFLGYTKAP
CEEEEEECCCCEEECCCCCEEEEECCCCHHHHHHCEECCCC
>Mature Secondary Structure
MQDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLR
CCCEEEEEECCCEEEEEHHHEECCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEEEE
VRTGPATYHSVIGGVLNGTTLNVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQP
EEECCHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCC
KQPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQGQKVQVISENSGWSKINYNGQ
CCCCCCCCCCCEEEEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCC
TGYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNTGNNSGNSSSILAYAKGMQGVPYV
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEE
WGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSNPQPGDLIYFQNTYKSGP
ECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
SHMGIYLGGGSFIQAGDKGVAIASLSNSYWSKHFLGYTKAP
CEEEEEECCCCEEECCCCCEEEEECCCCHHHHHHCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10206711 [H]