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The map label for this gene is licA [H]

Identifier: 49188048

GI number: 49188048

Start: 4936923

End: 4937240

Strand: Reverse

Name: licA [H]

Synonym: BAS5062

Alternate gene names: 49188048

Gene position: 4937240-4936923 (Counterclockwise)

Preceding gene: 49188049

Following gene: 49188045

Centisome position: 94.43

GC content: 40.88

Gene sequence:

>318_bases
ATGGATACGATAGAGACGAAAGCTTTTCATTTGATTTTGCATGGGGGAAATGCGAGAAGTTGTTCAATGGAAGCAATTGA
TTGCGCGAAGCGTGGGGAGTTTACAGAAGCAGAAGCGAAATTACAAGAAGCGTTAGAGGAATTAAAAGAGGCGCACCGTG
TACAAACGGATCTCATACAGAAAGAAGCTGGTGGTGAAAAAACTGAAGTAACTCTTCTGATGGTGCATGCGCAAGATCAT
TTAATGAATGCGATTACGGTGAAGGAATTAGCGAGTGAATTTGTAGAATTATATAGGAAGATGTCAGTGACTGAATGA

Upstream 100 bases:

>100_bases
ACTTGTTAACTTTGCGCTTGCATTCTTCATTTATTTACCGTTCTTAAAAATATGGGATAAACAAAAAGTAGCGGAAGAAA
AGGGGGAGTAAAGAAGGAAA

Downstream 100 bases:

>100_bases
ACCTTGCGTATGCAAGGTTTTTTTATGTATGTGTCTGTACCATCAGTGGAGGATTCGTTCCACTGATGGTATTTACAACC
CTCCTTTTTACAAATGAGTA

Product: PTS system cellobiose-specific transporter subunit IIA

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MDTIETKAFHLILHGGNARSCSMEAIDCAKRGEFTEAEAKLQEALEELKEAHRVQTDLIQKEAGGEKTEVTLLMVHAQDH
LMNAITVKELASEFVELYRKMSVTE

Sequences:

>Translated_105_residues
MDTIETKAFHLILHGGNARSCSMEAIDCAKRGEFTEAEAKLQEALEELKEAHRVQTDLIQKEAGGEKTEVTLLMVHAQDH
LMNAITVKELASEFVELYRKMSVTE
>Mature_105_residues
MDTIETKAFHLILHGGNARSCSMEAIDCAKRGEFTEAEAKLQEALEELKEAHRVQTDLIQKEAGGEKTEVTLLMVHAQDH
LMNAITVKELASEFVELYRKMSVTE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1447

COG function: function code G; Phosphotransferase system cellobiose-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=98, Percent_Identity=42.8571428571429, Blast_Score=83, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 11789; Mature: 11789

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIETKAFHLILHGGNARSCSMEAIDCAKRGEFTEAEAKLQEALEELKEAHRVQTDLIQ
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEAGGEKTEVTLLMVHAQDHLMNAITVKELASEFVELYRKMSVTE
HHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDTIETKAFHLILHGGNARSCSMEAIDCAKRGEFTEAEAKLQEALEELKEAHRVQTDLIQ
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEAGGEKTEVTLLMVHAQDHLMNAITVKELASEFVELYRKMSVTE
HHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]