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The map label for this gene is ywbA [H]

Identifier: 49188044

GI number: 49188044

Start: 4933321

End: 4934628

Strand: Reverse

Name: ywbA [H]

Synonym: BAS5058

Alternate gene names: 49188044

Gene position: 4934628-4933321 (Counterclockwise)

Preceding gene: 49188045

Following gene: 49188043

Centisome position: 94.38

GC content: 37.77

Gene sequence:

>1308_bases
ATGCAAAAATTTATTGCATTTATGGAGAAATATATTGTTCCTGTCGCTGGTAAAATCGGGTCGCAACGTCATTTAGCTGC
GATCCGTGACGGATTTATCGCAGTTATGCCACTTATTTTAGTTGGTGCACTGGCATCACTAATTAATGGTTTTCCATCTG
AGGCTTTCCAAGATTTCATGAAAGGTTTGTTTGGTGAAACGTGGAAACAAGTTGGCGGTGGAATGTGGACTGGTTCTTTC
GCGATTCTAGCACTAATCATAGCATTTACAACAAGTTATAACTTAGCAAAATCTTACGGCGTTGATGGTTTGTCAGCAGG
TATTATTTCATTTGGTGCGTTAATTATTCTTACGCCAACAACACCGAAAGAAGGCGGATTGAACTTAGCTTGGACAGGTG
CACAAGGGTTATTCGTAGCAATTATTGTAGCACTCCTTGTTACTGAAGTATTCCGTTTCTTCGTACAAAGAAACATTACT
TTTAAAATGCCTGATGGAGTACCACCAGCAGTTTTAAGATCTTTCGCAGCTATAGTTCCAGCATTTGTTATTTTAACAGT
AGTTGCAGGTATTCAATTAGCAGTGAAATTAGCCGGTACAAGTGTTCATGAATTTATCTTTAATACGATTCAATCGCCAC
TGCAAAGTTTAGCAGGGACATTACCAAGTGCAATTGTTATTGTACTCCTTGTTCATCTTCTTTGGTTCTTCGGTTTACAT
GGTCCAAATATCGTTGGTGGTATTATTGAGCCGTTATACTTACCAGCATTAGAGAAAAATATGAAGTTATTCCAAGGTGG
CACTTCTGCATTTGATGTTCCAAACATTGTTACAAAACCATTCTTTGATACTTTCGTATATCTTGGTGGTTCTGGTGCAA
CATTAGCGTTCTTAGTAGTGGTATTACTTGTAGCAAAAAGTGCACAATTACGCGGTGTATCTCGCTTATCAATTGGTCCA
GGTGCGTTCAACATTAACGAACCAGTAATCTTTGGTACACCAATTATTTTAAATCCAGTTTTATTCTTGCCGTTTATCAT
AACACCAATTGTATTGGTAATTACTTCTTATACAGCTATATCTATTGGCTGGGTACCAAAAACAGTTGCAATGATTCCAT
GGGCAACACCACCAATTATTAGTGGTTATCTTGTAACAGGTGGACATCTTTCAGGTGCAATTCTACAGTTATTCAACTTT
GTAATTGCAATGGTAATCTATTATCCATTCGTTGTGTTATGTGACCGTTCAGTTGTTCGTACTGAAAAAGCAGCAGCACA
AGGAAATAACAACTCTGTACCTATGTAA

Upstream 100 bases:

>100_bases
GGAATCGACGTTATCAATCCAATGCACTACGGCATGATGAATGGAGAAGCAGTTTTAGATCACGCATTAACACTTAAAAA
ATAATTAGGGGGGAAGCGAA

Downstream 100 bases:

>100_bases
CATAATAATTGTTCTCACAGATAACAGGATCTGTGAGAACAATTACCTTTATATCATGTTCAAAAAGATGAAATCCATCT
ACAAGAACACCAAACTATCA

Product: PTS system cellobiose-specific transporter subunit IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MQKFIAFMEKYIVPVAGKIGSQRHLAAIRDGFIAVMPLILVGALASLINGFPSEAFQDFMKGLFGETWKQVGGGMWTGSF
AILALIIAFTTSYNLAKSYGVDGLSAGIISFGALIILTPTTPKEGGLNLAWTGAQGLFVAIIVALLVTEVFRFFVQRNIT
FKMPDGVPPAVLRSFAAIVPAFVILTVVAGIQLAVKLAGTSVHEFIFNTIQSPLQSLAGTLPSAIVIVLLVHLLWFFGLH
GPNIVGGIIEPLYLPALEKNMKLFQGGTSAFDVPNIVTKPFFDTFVYLGGSGATLAFLVVVLLVAKSAQLRGVSRLSIGP
GAFNINEPVIFGTPIILNPVLFLPFIITPIVLVITSYTAISIGWVPKTVAMIPWATPPIISGYLVTGGHLSGAILQLFNF
VIAMVIYYPFVVLCDRSVVRTEKAAAQGNNNSVPM

Sequences:

>Translated_435_residues
MQKFIAFMEKYIVPVAGKIGSQRHLAAIRDGFIAVMPLILVGALASLINGFPSEAFQDFMKGLFGETWKQVGGGMWTGSF
AILALIIAFTTSYNLAKSYGVDGLSAGIISFGALIILTPTTPKEGGLNLAWTGAQGLFVAIIVALLVTEVFRFFVQRNIT
FKMPDGVPPAVLRSFAAIVPAFVILTVVAGIQLAVKLAGTSVHEFIFNTIQSPLQSLAGTLPSAIVIVLLVHLLWFFGLH
GPNIVGGIIEPLYLPALEKNMKLFQGGTSAFDVPNIVTKPFFDTFVYLGGSGATLAFLVVVLLVAKSAQLRGVSRLSIGP
GAFNINEPVIFGTPIILNPVLFLPFIITPIVLVITSYTAISIGWVPKTVAMIPWATPPIISGYLVTGGHLSGAILQLFNF
VIAMVIYYPFVVLCDRSVVRTEKAAAQGNNNSVPM
>Mature_435_residues
MQKFIAFMEKYIVPVAGKIGSQRHLAAIRDGFIAVMPLILVGALASLINGFPSEAFQDFMKGLFGETWKQVGGGMWTGSF
AILALIIAFTTSYNLAKSYGVDGLSAGIISFGALIILTPTTPKEGGLNLAWTGAQGLFVAIIVALLVTEVFRFFVQRNIT
FKMPDGVPPAVLRSFAAIVPAFVILTVVAGIQLAVKLAGTSVHEFIFNTIQSPLQSLAGTLPSAIVIVLLVHLLWFFGLH
GPNIVGGIIEPLYLPALEKNMKLFQGGTSAFDVPNIVTKPFFDTFVYLGGSGATLAFLVVVLLVAKSAQLRGVSRLSIGP
GAFNINEPVIFGTPIILNPVLFLPFIITPIVLVITSYTAISIGWVPKTVAMIPWATPPIISGYLVTGGHLSGAILQLFNF
VIAMVIYYPFVVLCDRSVVRTEKAAAQGNNNSVPM

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=451, Percent_Identity=35.6984478935698, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 46429; Mature: 46429

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKFIAFMEKYIVPVAGKIGSQRHLAAIRDGFIAVMPLILVGALASLINGFPSEAFQDFM
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KGLFGETWKQVGGGMWTGSFAILALIIAFTTSYNLAKSYGVDGLSAGIISFGALIILTPT
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCEEEEEECC
TPKEGGLNLAWTGAQGLFVAIIVALLVTEVFRFFVQRNITFKMPDGVPPAVLRSFAAIVP
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
AFVILTVVAGIQLAVKLAGTSVHEFIFNTIQSPLQSLAGTLPSAIVIVLLVHLLWFFGLH
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPNIVGGIIEPLYLPALEKNMKLFQGGTSAFDVPNIVTKPFFDTFVYLGGSGATLAFLVV
CCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
VLLVAKSAQLRGVSRLSIGPGAFNINEPVIFGTPIILNPVLFLPFIITPIVLVITSYTAI
HHHHHCCHHHCCCCEEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHE
SIGWVPKTVAMIPWATPPIISGYLVTGGHLSGAILQLFNFVIAMVIYYPFVVLCDRSVVR
EECCCCHHHHHCCCCCCCHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TEKAAAQGNNNSVPM
HHHHHHCCCCCCCCC
>Mature Secondary Structure
MQKFIAFMEKYIVPVAGKIGSQRHLAAIRDGFIAVMPLILVGALASLINGFPSEAFQDFM
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KGLFGETWKQVGGGMWTGSFAILALIIAFTTSYNLAKSYGVDGLSAGIISFGALIILTPT
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCEEEEEECC
TPKEGGLNLAWTGAQGLFVAIIVALLVTEVFRFFVQRNITFKMPDGVPPAVLRSFAAIVP
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
AFVILTVVAGIQLAVKLAGTSVHEFIFNTIQSPLQSLAGTLPSAIVIVLLVHLLWFFGLH
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPNIVGGIIEPLYLPALEKNMKLFQGGTSAFDVPNIVTKPFFDTFVYLGGSGATLAFLVV
CCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
VLLVAKSAQLRGVSRLSIGPGAFNINEPVIFGTPIILNPVLFLPFIITPIVLVITSYTAI
HHHHHCCHHHCCCCEEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHE
SIGWVPKTVAMIPWATPPIISGYLVTGGHLSGAILQLFNFVIAMVIYYPFVVLCDRSVVR
EECCCCHHHHHCCCCCCCHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TEKAAAQGNNNSVPM
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]