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The map label for this gene is expZ [H]

Identifier: 49188014

GI number: 49188014

Start: 4898841

End: 4900475

Strand: Direct

Name: expZ [H]

Synonym: BAS5028

Alternate gene names: 49188014

Gene position: 4898841-4900475 (Clockwise)

Preceding gene: 49188013

Following gene: 49188032

Centisome position: 93.69

GC content: 37.74

Gene sequence:

>1635_bases
ATGACTATTTTATTCGCACGTAATATTGAGAAGGGCTTTGGTGATCGCACACTATTTACGTTACCGTCACTGGAAATTCA
AGCACAGGATCGCATAGGAATTGTCGGCGTCAACGGGGCTGGTAAATCTACGTTACTACAAATATTAAGTAAAGAAATAG
AAGCTGACAAAGGCATAGTAACTCACCATAGCTCTATCAGCATCATTCCTCAAATTAGCGAGGAATTACCCAAAGTCGCT
TCTTCTACAGCAAAAGGAAAATGGAATATTTCAAACATCTCAAATTCAATGAGCGGCGGGGAACGAATGCGTCTAAAGAT
TGCCCATGCTCTCGAACAAGATGCAGGCATTCTATTCGCTGATGAACCAACAAGCCACTTAGATATGTTCGGTACAGAGC
AATTAGAAAAGGCACTTTTATCTTATAAAGGTGCACTTGTTTTAATATCACATGATCGTGAATTTCTAGATAATATATGT
ACAAAAATCATTGAAATTGAAGACGGGATAATTCAAGAATATAAAGGAAACTATTCCAACTATCGAAAGCAAAAAGAACG
TGAACGAACACAAAAACAAGCAGAATACGAGCAGTATATAAACGAAAAAGAGCGTTTAGAGAAGTCCATTTTACAAAAAA
AGCAACGTGCTTCTAGCATGACAAAAATCCCAACACGGTTCAGTTCATCTGAATCTAAACTTTATAAATTAAGTGGGGCT
AATGGCCAAGAACAGGTTAGTAAAGCAGCAAAAGCATTAGAGACACGTCTTGAAAAACTAGAAAAGAAAGAAAAGCCAAA
GGAGCTTTCTCAAGCACAGTTTGACGTACAATACCATACACCCATTCATAGTAAAGTGGCAGTACAGTTCAATAAAGCAA
CAAAGAAAATAGGTGACCTCACACTATTTAAAAATATGAATGGAACGATTGCTCCTGGTGCAAAGCTTGCTATTTTAGGG
GCAAACGGAAGTGGAAAAACGACCCTGTTTAACATGCTTCTCGCAAATGAGCGTGGCATTCAGCTTTCAAAAAGTTGTAA
GATTGGGTACTTTGAACAAACACTATCCATTTTAAAAACAGATAAAACCATTTTAGAAAATGTTCTAGAAGAAACAAACT
ATACAGAGTCGTTCGTTCGCACAATACTTGCAAGGCTTCTATTCCGCCGTGAAGATGTTCATAAACCTGTGCACGTTCTA
AGCGGAGGTGAGCGAATGAAGGTTGCACTCGCAAAAGTATTTTTAGGAAACTATAATATGCTTCTGCTCGATGAACCGAC
AAACTATTTAGACTTAGCGACGCAAGAAGAATTAGAAAGCATGCTACAAGAATATCCTGGCACTATACTTTTCATTAGCC
ATGACCGTGCCTTCATTCGTTCTGTTGCAGACCATATTCTACAAGTAGATGAAAGTGAACCAAGAGTATTCCACGGTAAT
TACGAGCAATACACAAACAGAACAGCCGATGCTTCTGTAAACGTTACTGCACAAGAATTATTACGATTACAAACAAAATT
AACAGAAATCATCGGCCGAATTTCCATACCAAATCATCACGATGATATCACATCTCTCGAACAAGAATACGAAACATTAT
TAGTTAAAATCCGGAAATGTAAAGAAGCACTCTAA

Upstream 100 bases:

>100_bases
TCTTTCGAAACGATCATGTAAAAAAATCGTTTATTTATGTACGATTTTTACATGCAAGGGCGACGTTTATCCTCTCTAGT
GAAACTAGGGAGGTTTTTTT

Downstream 100 bases:

>100_bases
TGTCTTCCCTATATATCGACGGGACCTTCCGCATTTCCCAAGAAATATTGAATCTTCGACATAGCATACAAAAAGCCGTG
CAGTTCATCAGCACGGCCTT

Product: macrolide efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MTILFARNIEKGFGDRTLFTLPSLEIQAQDRIGIVGVNGAGKSTLLQILSKEIEADKGIVTHHSSISIIPQISEELPKVA
SSTAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFADEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNIC
TKIIEIEDGIIQEYKGNYSNYRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGA
NGQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDLTLFKNMNGTIAPGAKLAILG
ANGSGKTTLFNMLLANERGIQLSKSCKIGYFEQTLSILKTDKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVL
SGGERMKVALAKVFLGNYNMLLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGN
YEQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKCKEAL

Sequences:

>Translated_544_residues
MTILFARNIEKGFGDRTLFTLPSLEIQAQDRIGIVGVNGAGKSTLLQILSKEIEADKGIVTHHSSISIIPQISEELPKVA
SSTAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFADEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNIC
TKIIEIEDGIIQEYKGNYSNYRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGA
NGQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDLTLFKNMNGTIAPGAKLAILG
ANGSGKTTLFNMLLANERGIQLSKSCKIGYFEQTLSILKTDKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVL
SGGERMKVALAKVFLGNYNMLLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGN
YEQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKCKEAL
>Mature_543_residues
TILFARNIEKGFGDRTLFTLPSLEIQAQDRIGIVGVNGAGKSTLLQILSKEIEADKGIVTHHSSISIIPQISEELPKVAS
STAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFADEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNICT
KIIEIEDGIIQEYKGNYSNYRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGAN
GQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDLTLFKNMNGTIAPGAKLAILGA
NGSGKTTLFNMLLANERGIQLSKSCKIGYFEQTLSILKTDKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVLS
GGERMKVALAKVFLGNYNMLLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGNY
EQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKCKEAL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=398, Percent_Identity=28.643216080402, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI10947137, Length=524, Percent_Identity=26.9083969465649, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI27881506, Length=524, Percent_Identity=26.9083969465649, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI10947135, Length=407, Percent_Identity=28.009828009828, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI69354671, Length=407, Percent_Identity=28.009828009828, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1789751, Length=554, Percent_Identity=30.5054151624549, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1787041, Length=550, Percent_Identity=29.0909090909091, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI2367384, Length=432, Percent_Identity=33.5648148148148, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1787182, Length=533, Percent_Identity=26.4540337711069, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1789672, Length=212, Percent_Identity=27.3584905660377, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788225, Length=220, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788165, Length=210, Percent_Identity=25.2380952380952, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787029, Length=214, Percent_Identity=26.6355140186916, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787164, Length=198, Percent_Identity=26.7676767676768, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17559834, Length=401, Percent_Identity=26.4339152119701, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17555318, Length=525, Percent_Identity=27.047619047619, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17553372, Length=404, Percent_Identity=28.4653465346535, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320874, Length=404, Percent_Identity=27.970297029703, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6321121, Length=421, Percent_Identity=28.5035629453682, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6323278, Length=178, Percent_Identity=31.4606741573034, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324314, Length=180, Percent_Identity=30, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325030, Length=203, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24666836, Length=414, Percent_Identity=28.2608695652174, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24642252, Length=531, Percent_Identity=26.7419962335217, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI18859989, Length=531, Percent_Identity=26.7419962335217, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24641342, Length=416, Percent_Identity=27.8846153846154, Blast_Score=147, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 61408; Mature: 61277

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILFARNIEKGFGDRTLFTLPSLEIQAQDRIGIVGVNGAGKSTLLQILSKEIEADKGIV
CEEEEECCCCCCCCCCEEEECCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCEE
THHSSISIIPQISEELPKVASSTAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFA
EECCCEEECHHHHHHHHHHHHCCCCCCEEHHHHCCCCCCCHHEEHHHHHHHHHCCCEEEE
DEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNICTKIIEIEDGIIQEYKGNYSN
CCCCHHHHHCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCHHHHHHCCCHHH
YRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
NGQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDL
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCEEEEEHHHHHHHHCE
TLFKNMNGTIAPGAKLAILGANGSGKTTLFNMLLANERGIQLSKSCKIGYFEQTLSILKT
EEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHC
DKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVLSGGERMKVALAKVFLGNYNM
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCE
LLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGN
EEEECCCCHHHCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEECC
YEQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKC
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
KEAL
HHCC
>Mature Secondary Structure 
TILFARNIEKGFGDRTLFTLPSLEIQAQDRIGIVGVNGAGKSTLLQILSKEIEADKGIV
EEEEECCCCCCCCCCEEEECCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCEE
THHSSISIIPQISEELPKVASSTAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFA
EECCCEEECHHHHHHHHHHHHCCCCCCEEHHHHCCCCCCCHHEEHHHHHHHHHCCCEEEE
DEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNICTKIIEIEDGIIQEYKGNYSN
CCCCHHHHHCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCHHHHHHCCCHHH
YRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
NGQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDL
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCEEEEEHHHHHHHHCE
TLFKNMNGTIAPGAKLAILGANGSGKTTLFNMLLANERGIQLSKSCKIGYFEQTLSILKT
EEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHC
DKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVLSGGERMKVALAKVFLGNYNM
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCE
LLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGN
EEEECCCCHHHCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEECC
YEQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKC
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
KEAL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]