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The map label for this gene is arlR [H]

Identifier: 49187941

GI number: 49187941

Start: 4834633

End: 4835310

Strand: Reverse

Name: arlR [H]

Synonym: BAS4954

Alternate gene names: 49187941

Gene position: 4835310-4834633 (Counterclockwise)

Preceding gene: 49187942

Following gene: 49187940

Centisome position: 92.48

GC content: 33.63

Gene sequence:

>678_bases
GTGAGGCAGGTGTTAGTAATTAAGAATGAACGGTCTTTAGCAAAGAAAATCGTAAGCGGTTTAACGGAAGAAGGCCATTT
CATTTTAAAACTTCACAATGAAAACGAAGGTTTAAATATAATATATGAACAAGATTGGGATATTATCATATTAGATTGGG
ATTCATTAAGCATATCCGGACCAGAAATTTGCAGACAAATACGACTTGTTAAAATGACACCGATCATTATTGTGACCGAC
AATATTTCTAGTAAGGATTGCGTGGCAGGGTTACAAGCAGGAGCTGATGATTATATAAGAAAACCATTTGCGAAAGAAGA
ACTAGTAGCAAGGGTTCAAGCTATTTTAAGGAGAAGTGGCTGTAACCAGCAACATGAGACAACCTTTTTTCAGTTTAAAG
ATCTCTTTGTTGATGCATCTAGCAATATTGTGAAAAAAGGTGGTAAAAATCTTTCACTTACTAAGCGCGAGTACGATTTA
CTTGTATTTTTAATTAAGAATAAAAATACAATATTGAGCCGTGAAATGCTTTTGAATCAAGTATGGGGATATAACGTAGT
CGTAAATCCGAATGTAGTAGACTTATATATTGGATATGTAAGAAAAAAGTTAAAGTGCGAGAAGAAAGACAGATATATTC
AAACGATACATGGTAGAGGTTATTCAATGATTGAATGA

Upstream 100 bases:

>100_bases
AATGGCTTTTTTAGGAATTTAACATTTATAAAACTTAAATTATTTTTTTGAGATGATTTTTTATGTAACTAAGTTATATT
GAAGTAGAGGTGAACCATCG

Downstream 100 bases:

>100_bases
TAGAAATAAGATAATAGAAAAAACGAGTAAAACGTTGCATTTAGTTTTATTCGTTTTTTTCTTTAAATCAATAACCAAAT
AGTTTTTGAGAAGTATGAAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRQVLVIKNERSLAKKIVSGLTEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISGPEICRQIRLVKMTPIIIVTD
NISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSGCNQQHETTFFQFKDLFVDASSNIVKKGGKNLSLTKREYDL
LVFLIKNKNTILSREMLLNQVWGYNVVVNPNVVDLYIGYVRKKLKCEKKDRYIQTIHGRGYSMIE

Sequences:

>Translated_225_residues
MRQVLVIKNERSLAKKIVSGLTEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISGPEICRQIRLVKMTPIIIVTD
NISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSGCNQQHETTFFQFKDLFVDASSNIVKKGGKNLSLTKREYDL
LVFLIKNKNTILSREMLLNQVWGYNVVVNPNVVDLYIGYVRKKLKCEKKDRYIQTIHGRGYSMIE
>Mature_225_residues
MRQVLVIKNERSLAKKIVSGLTEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISGPEICRQIRLVKMTPIIIVTD
NISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSGCNQQHETTFFQFKDLFVDASSNIVKKGGKNLSLTKREYDL
LVFLIKNKNTILSREMLLNQVWGYNVVVNPNVVDLYIGYVRKKLKCEKKDRYIQTIHGRGYSMIE

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=34.0807174887892, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.2342342342342, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=31.1111111111111, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=32.2869955156951, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=28.5714285714286, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=32.1428571428571, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI2367329, Length=174, Percent_Identity=35.632183908046, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=29.4372294372294, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=30.5309734513274, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=30.1801801801802, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=28.6363636363636, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=28.6995515695067, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=25.2212389380531, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25918; Mature: 25918

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQVLVIKNERSLAKKIVSGLTEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISG
CCEEEEEECCHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCC
PEICRQIRLVKMTPIIIVTDNISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSG
HHHHHHHEEEEECEEEEEECCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCC
CNQQHETTFFQFKDLFVDASSNIVKKGGKNLSLTKREYDLLVFLIKNKNTILSREMLLNQ
CCCCHHHHHHEEEEHEEECCCHHHHCCCCCCEEEEECEEEEEEEEECCCCHHHHHHHHHH
VWGYNVVVNPNVVDLYIGYVRKKLKCEKKDRYIQTIHGRGYSMIE
HCCCEEEECCCHHHHHHHHHHHHHCCCHHHHEEEEECCCCCCCCC
>Mature Secondary Structure
MRQVLVIKNERSLAKKIVSGLTEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISG
CCEEEEEECCHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCC
PEICRQIRLVKMTPIIIVTDNISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSG
HHHHHHHEEEEECEEEEEECCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCC
CNQQHETTFFQFKDLFVDASSNIVKKGGKNLSLTKREYDLLVFLIKNKNTILSREMLLNQ
CCCCHHHHHHEEEEHEEECCCHHHHCCCCCCEEEEECEEEEEEEEECCCCHHHHHHHHHH
VWGYNVVVNPNVVDLYIGYVRKKLKCEKKDRYIQTIHGRGYSMIE
HCCCEEEECCCHHHHHHHHHHHHHCCCHHHHEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA