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The map label for this gene is speG [H]

Identifier: 49187933

GI number: 49187933

Start: 4826658

End: 4827173

Strand: Reverse

Name: speG [H]

Synonym: BAS4945

Alternate gene names: 49187933

Gene position: 4827173-4826658 (Counterclockwise)

Preceding gene: 49187934

Following gene: 49187932

Centisome position: 92.32

GC content: 35.27

Gene sequence:

>516_bases
ATGAGTCAGGAATTGAAATTGCGTCCATTAGAGCGAGAAGATTTAAAGTTTGTACACGAACTTAATAATAATGCACATAT
TATGTCGTATTGGTTTGAAGAGCCGTATGAGGCATTTGTGGAGCTGCAAGACTTATACGATAAACATATACATGATCAAA
GTGAACGCCGATTTATCGTTGAAAAAGATAATGAAATGGTTGGGTTAGTTGAGTTAGTGGAAATCGATTATATTCACCGT
AGAACGGAATTCCAAATTATTATTGATCCGAATTATCAAGGATATGGTTATGCTGCGGAAGCGACGCGTTTAGCGATGGA
TTACGCTTTTTCTGTACTAAATATGCATAAGATTTATTTAGTGGTGGATAAGGAAAATGAAAAAGCGGTACATGTTTATA
AAAAGGTTGGATTTATGGTGGAAGGTGAACTGTTAGACGAGTTTTTCGTTGATGGTAACTATCATAATGCGATAAGAATG
TGTATGTTCCAAAAGGCATACTTTGGCACAAAATAA

Upstream 100 bases:

>100_bases
TTAAAGTTACTTGAAAGTTTACAATAAAATTAGGGCGTTTGAAATTGAAAAAAATTGAGAAATTAAGTAAAGAGGTTTCT
TTTACTTGGAGGTTATAGAA

Downstream 100 bases:

>100_bases
CTAATTGGAAGAGATATAGATAATATTTTATCTATAGCTTTTTTGTCATGCGAATAACAGCGTTTTTTTATTGTTAAACG
ATAAAATGTTATTGACTTGT

Product: spermidine N1-acetyltransferase

Products: NA

Alternate protein names: Diamine acetyltransferase; SAT [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSQELKLRPLEREDLKFVHELNNNAHIMSYWFEEPYEAFVELQDLYDKHIHDQSERRFIVEKDNEMVGLVELVEIDYIHR
RTEFQIIIDPNYQGYGYAAEATRLAMDYAFSVLNMHKIYLVVDKENEKAVHVYKKVGFMVEGELLDEFFVDGNYHNAIRM
CMFQKAYFGTK

Sequences:

>Translated_171_residues
MSQELKLRPLEREDLKFVHELNNNAHIMSYWFEEPYEAFVELQDLYDKHIHDQSERRFIVEKDNEMVGLVELVEIDYIHR
RTEFQIIIDPNYQGYGYAAEATRLAMDYAFSVLNMHKIYLVVDKENEKAVHVYKKVGFMVEGELLDEFFVDGNYHNAIRM
CMFQKAYFGTK
>Mature_170_residues
SQELKLRPLEREDLKFVHELNNNAHIMSYWFEEPYEAFVELQDLYDKHIHDQSERRFIVEKDNEMVGLVELVEIDYIHRR
TEFQIIIDPNYQGYGYAAEATRLAMDYAFSVLNMHKIYLVVDKENEKAVHVYKKVGFMVEGELLDEFFVDGNYHNAIRMC
MFQKAYFGTK

Specific function: Regulates polyamine concentration by their degradation. Acts on spermidine, forming N(1)- and N(8)-acetylspermidine [H]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1787867, Length=168, Percent_Identity=69.6428571428571, Blast_Score=262, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.57 [H]

Molecular weight: Translated: 20492; Mature: 20360

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQELKLRPLEREDLKFVHELNNNAHIMSYWFEEPYEAFVELQDLYDKHIHDQSERRFIV
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEE
EKDNEMVGLVELVEIDYIHRRTEFQIIIDPNYQGYGYAAEATRLAMDYAFSVLNMHKIYL
ECCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEE
VVDKENEKAVHVYKKVGFMVEGELLDEFFVDGNYHNAIRMCMFQKAYFGTK
EEECCCCCHHHHHHHHCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQELKLRPLEREDLKFVHELNNNAHIMSYWFEEPYEAFVELQDLYDKHIHDQSERRFIV
CCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEE
EKDNEMVGLVELVEIDYIHRRTEFQIIIDPNYQGYGYAAEATRLAMDYAFSVLNMHKIYL
ECCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEE
VVDKENEKAVHVYKKVGFMVEGELLDEFFVDGNYHNAIRMCMFQKAYFGTK
EEECCCCCHHHHHHHHCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]