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The map label for this gene is tlpC [H]

Identifier: 49187927

GI number: 49187927

Start: 4822275

End: 4823777

Strand: Reverse

Name: tlpC [H]

Synonym: BAS4939

Alternate gene names: 49187927

Gene position: 4823777-4822275 (Counterclockwise)

Preceding gene: 49187928

Following gene: 49187926

Centisome position: 92.26

GC content: 35.33

Gene sequence:

>1503_bases
ATGGAATGGTTAAAGAAAACTTGTTTTTCTAACCTTGAGAAAGAATCACAGAAAAATCATTTATTGCTGTTTATTACGAT
TTGTAGTTTCTTCCTTGGAATCATCGCGATTGGGTATTACGGATATATTTTTACGGCGAGAGCAATCGCGTTTTGGGTTT
GTGGTATTTCTGTCGTTGTATTTGGGACACTTCTTACTTTTATAGAAAGCATGGAAGCGATGTATAAATATATCATGACA
TTTATGTTACTTACGATGTCTTTCATTATGGTACAAGCTTTTAATGAAAGCCCGGCTGTATTTCAAATGGTCTATTTTAC
ATTAGCCGTTTCACTTATTTATTTAAGTGAGCGTCTCGTTGTAATTCTCGGCGGAGTAGCGGTTGTGATCACATTTATTC
TTTGTAGTTATTGGCCGAAGCAATTTTTTGCTTATACAGCAGCATCTGAAGCTGCAAACTTCGCAAGTTTGTTAGCGATC
GTTACGATTGCAATGTGGGGCGTCACGAAGATTGGCTCTAACTTGCTGGCTCGCTTAAGCGATGAGAAGCAAGAAGTAAT
GAGAAAAGCTCAGGAGTTAGAAGAAACGCAAAGACTTATTGAGGAAACGGTTGTGAAACTAGATAGTAATTTCAATTATT
TAAGACAAAATATGAATACATCGATGGAGTCGATGAGTGAAATCAATTTTGCTTTTGAAGAGGTAGCAGTTGGCACTCAA
TCACAATCAGAGATGATGTATCGTTCGGTAGAAGTATTGAATGATATGGAGGGAAATATTGAACAAATCATTTCTCAAGT
AAGAAATGCATCGATTCGTATTGATGAAAGCTTAGAAATTTCAAAGGGTAGTGTACATACTCTACGAAGTTTTGAAGCGA
ATATGAGAAGTTTAAATGATATTGTTTCACAATTAGGAATTATATTTAGAGATTTAATGATGCAATCGAAACAAATTAAT
GAAATTGTAGATGTAATAACGAATATTTCAAGTCAGACGAGTTTGCTAGCTTTAAATGCAAATATTGAAGCTGCAAGAGC
AGGTGAGCATGGAAAAGGATTTGCTATTGTAGCGAATGAAGTACTAAAGCTTGCTGAGGAATCGAATCGTTCTGCGGGAA
GAATTCAAGGGATTTTGAAGGAGTTTAGTAATCAAGCAAGTAAGGTAGAAGTGCAAGTAGAGAAATCAGAAAGAGTACAA
GAAGAATGTAATGAAATGTTAGCAAGTGTTTTAACAAATGTAACGGATTTAGGGAAATTTATTGATGAGATTAATGATGT
AATGAGAGAAATCGTTGGTCATCAAGAAAGTTTCCAAGTTAAAACGACGAATATCGTAAAGGATGTTACACATGCTTCCA
ATGTAATCCAGCAAACTTCTGCGGCTACAGAAGAAGTGTTAGCAAGTGTGGAAGAAGAAAAACATCGAAACGATACATCT
GTGAAGACATTACATACGGTTAGCGAGCAAGTGAAATTGTTAGAAGATATTTTAGAAAAGTAA

Upstream 100 bases:

>100_bases
AATGTGCAAGGAAAAGATTTAAAGTTTGAGAATAGTGATCATAACCCAGTGAGTGCGGTATTTAAGTTGAAGTAATTAAG
TGCAGAAGGTGGGACTATAT

Downstream 100 bases:

>100_bases
TATCACTTAAAAAGAGCACAATGTTTGTGCTCTTTTTTCATTTAAATGAAGACTTGCTCGGAATTTAATTGCTTTTCTGC
GCGTTTTCTGCCAAGCTTAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MEWLKKTCFSNLEKESQKNHLLLFITICSFFLGIIAIGYYGYIFTARAIAFWVCGISVVVFGTLLTFIESMEAMYKYIMT
FMLLTMSFIMVQAFNESPAVFQMVYFTLAVSLIYLSERLVVILGGVAVVITFILCSYWPKQFFAYTAASEAANFASLLAI
VTIAMWGVTKIGSNLLARLSDEKQEVMRKAQELEETQRLIEETVVKLDSNFNYLRQNMNTSMESMSEINFAFEEVAVGTQ
SQSEMMYRSVEVLNDMEGNIEQIISQVRNASIRIDESLEISKGSVHTLRSFEANMRSLNDIVSQLGIIFRDLMMQSKQIN
EIVDVITNISSQTSLLALNANIEAARAGEHGKGFAIVANEVLKLAEESNRSAGRIQGILKEFSNQASKVEVQVEKSERVQ
EECNEMLASVLTNVTDLGKFIDEINDVMREIVGHQESFQVKTTNIVKDVTHASNVIQQTSAATEEVLASVEEEKHRNDTS
VKTLHTVSEQVKLLEDILEK

Sequences:

>Translated_500_residues
MEWLKKTCFSNLEKESQKNHLLLFITICSFFLGIIAIGYYGYIFTARAIAFWVCGISVVVFGTLLTFIESMEAMYKYIMT
FMLLTMSFIMVQAFNESPAVFQMVYFTLAVSLIYLSERLVVILGGVAVVITFILCSYWPKQFFAYTAASEAANFASLLAI
VTIAMWGVTKIGSNLLARLSDEKQEVMRKAQELEETQRLIEETVVKLDSNFNYLRQNMNTSMESMSEINFAFEEVAVGTQ
SQSEMMYRSVEVLNDMEGNIEQIISQVRNASIRIDESLEISKGSVHTLRSFEANMRSLNDIVSQLGIIFRDLMMQSKQIN
EIVDVITNISSQTSLLALNANIEAARAGEHGKGFAIVANEVLKLAEESNRSAGRIQGILKEFSNQASKVEVQVEKSERVQ
EECNEMLASVLTNVTDLGKFIDEINDVMREIVGHQESFQVKTTNIVKDVTHASNVIQQTSAATEEVLASVEEEKHRNDTS
VKTLHTVSEQVKLLEDILEK
>Mature_500_residues
MEWLKKTCFSNLEKESQKNHLLLFITICSFFLGIIAIGYYGYIFTARAIAFWVCGISVVVFGTLLTFIESMEAMYKYIMT
FMLLTMSFIMVQAFNESPAVFQMVYFTLAVSLIYLSERLVVILGGVAVVITFILCSYWPKQFFAYTAASEAANFASLLAI
VTIAMWGVTKIGSNLLARLSDEKQEVMRKAQELEETQRLIEETVVKLDSNFNYLRQNMNTSMESMSEINFAFEEVAVGTQ
SQSEMMYRSVEVLNDMEGNIEQIISQVRNASIRIDESLEISKGSVHTLRSFEANMRSLNDIVSQLGIIFRDLMMQSKQIN
EIVDVITNISSQTSLLALNANIEAARAGEHGKGFAIVANEVLKLAEESNRSAGRIQGILKEFSNQASKVEVQVEKSERVQ
EECNEMLASVLTNVTDLGKFIDEINDVMREIVGHQESFQVKTTNIVKDVTHASNVIQQTSAATEEVLASVEEEKHRNDTS
VKTLHTVSEQVKLLEDILEK

Specific function: Mediates Taxis Toward Dipeptides VIa An Interaction With The Periplasmic Dipeptide-Binding Protein. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Transduce A Signal From The Outsid

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=265, Percent_Identity=26.4150943396226, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787690, Length=336, Percent_Identity=25.8928571428571, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI2367378, Length=184, Percent_Identity=31.5217391304348, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788195, Length=247, Percent_Identity=27.9352226720648, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789453, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 56259; Mature: 56259

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]