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The map label for this gene is yclJ [H]

Identifier: 49187888

GI number: 49187888

Start: 4780492

End: 4781157

Strand: Direct

Name: yclJ [H]

Synonym: BAS4900

Alternate gene names: 49187888

Gene position: 4780492-4781157 (Clockwise)

Preceding gene: 49187887

Following gene: 49187889

Centisome position: 91.43

GC content: 33.63

Gene sequence:

>666_bases
ATGACGCATATACTGGTGATTGAAGACAACCCAGATATACAAGAACTGATTCGTGAATTTCTAATGGCACAAAACTTTAC
TGTTGATGTCGTTGGTGCTGGGACAGAAGGTATACTTCTTTTCCAAAAAAATTCATACGATCTTGTCCTCCTTGATGTGA
TGTTACCAGATATAGATGGCTATAGTATTTGTAAAATTATGCGAGGACAATCTGATGTACCAATCATTATGTTAACAGGC
TCACATAATGAAGAAAGTGAAATTAAAGGATTTGAATTAGGTATTGATGACTATATTACGAAACCGTTCCATTACACCGT
ATTTATTAAACGTGTAGAAGCTGTATTAAGAAGGGCAGCAACGAAGGAAGCCGAGGCTGCAACTATACTACAATTCCATG
AATTGATGTTAAATTCTACAGCATATGCCGCTTATGTTCATGGTAATCAAATTGAATTGACAACAAAAGAATTTGAAATT
ATTTATACTTTACTGCAAAATCGAGGAAAAGTATTATCAAGAAGTGATTTGTTGAATAAGGTATGGGGCTATGAACATTA
TGGTGATGTAAGAGTTATAGATACACATATTAAAAACTTACGAAAAAAATTAGGAATTCCTTATATTAAAACGGTGAAAG
GCATTGGCTACAAAATCGAATCGTAG

Upstream 100 bases:

>100_bases
TTTATGGCGGGGGCTTATTATATGTATAAACAATCTGATTCATCCGAAAAATGATGAATTCGAATATTGCAGTTAAAAGC
GTTATTTAGGAGGTGTTACT

Downstream 100 bases:

>100_bases
CAAAGACAACATCACCAAAAATATTTTCATCAAAACCTTATTATTTTGTATTCTTTTATCACTTTGTCTTTATCAAATTA
TTTACTTCTTAGCTTCAGAC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTHILVIEDNPDIQELIREFLMAQNFTVDVVGAGTEGILLFQKNSYDLVLLDVMLPDIDGYSICKIMRGQSDVPIIMLTG
SHNEESEIKGFELGIDDYITKPFHYTVFIKRVEAVLRRAATKEAEAATILQFHELMLNSTAYAAYVHGNQIELTTKEFEI
IYTLLQNRGKVLSRSDLLNKVWGYEHYGDVRVIDTHIKNLRKKLGIPYIKTVKGIGYKIES

Sequences:

>Translated_221_residues
MTHILVIEDNPDIQELIREFLMAQNFTVDVVGAGTEGILLFQKNSYDLVLLDVMLPDIDGYSICKIMRGQSDVPIIMLTG
SHNEESEIKGFELGIDDYITKPFHYTVFIKRVEAVLRRAATKEAEAATILQFHELMLNSTAYAAYVHGNQIELTTKEFEI
IYTLLQNRGKVLSRSDLLNKVWGYEHYGDVRVIDTHIKNLRKKLGIPYIKTVKGIGYKIES
>Mature_220_residues
THILVIEDNPDIQELIREFLMAQNFTVDVVGAGTEGILLFQKNSYDLVLLDVMLPDIDGYSICKIMRGQSDVPIIMLTGS
HNEESEIKGFELGIDDYITKPFHYTVFIKRVEAVLRRAATKEAEAATILQFHELMLNSTAYAAYVHGNQIELTTKEFEII
YTLLQNRGKVLSRSDLLNKVWGYEHYGDVRVIDTHIKNLRKKLGIPYIKTVKGIGYKIES

Specific function: Could be member of the two-component regulatory system yclK/yclJ [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=35.1351351351351, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=35.3982300884956, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=31.0502283105023, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=35.2678571428571, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=37.0044052863436, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=33.1858407079646, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=33.7899543378995, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=220, Percent_Identity=32.7272727272727, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=31.5315315315315, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=31.390134529148, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=30.7017543859649, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.8701298701299, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=27.8026905829596, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788550, Length=144, Percent_Identity=22.9166666666667, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=102, Percent_Identity=35.2941176470588, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25198; Mature: 25066

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHILVIEDNPDIQELIREFLMAQNFTVDVVGAGTEGILLFQKNSYDLVLLDVMLPDIDG
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCC
YSICKIMRGQSDVPIIMLTGSHNEESEIKGFELGIDDYITKPFHYTVFIKRVEAVLRRAA
HHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHHHH
TKEAEAATILQFHELMLNSTAYAAYVHGNQIELTTKEFEIIYTLLQNRGKVLSRSDLLNK
CCCHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHH
VWGYEHYGDVRVIDTHIKNLRKKLGIPYIKTVKGIGYKIES
HCCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHCCCCEEECC
>Mature Secondary Structure 
THILVIEDNPDIQELIREFLMAQNFTVDVVGAGTEGILLFQKNSYDLVLLDVMLPDIDG
EEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCC
YSICKIMRGQSDVPIIMLTGSHNEESEIKGFELGIDDYITKPFHYTVFIKRVEAVLRRAA
HHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHHHH
TKEAEAATILQFHELMLNSTAYAAYVHGNQIELTTKEFEIIYTLLQNRGKVLSRSDLLNK
CCCHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHH
VWGYEHYGDVRVIDTHIKNLRKKLGIPYIKTVKGIGYKIES
HCCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]