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The map label for this gene is oxaA2

Identifier: 49187877

GI number: 49187877

Start: 4771678

End: 4772460

Strand: Reverse

Name: oxaA2

Synonym: BAS4889

Alternate gene names: 49187877

Gene position: 4772460-4771678 (Counterclockwise)

Preceding gene: 49187878

Following gene: 49187876

Centisome position: 91.27

GC content: 36.65

Gene sequence:

>783_bases
ATGTTAAAATCATACCGAGCTGTGCTCGTTAGTTTATCATTATTACTTGTTTTTGTTTTATCTGGTTGCAGTAATGCAAC
CCCAATTGATGCACATAGTACGGGAATTTGGGATCATTACTTTGTATATCCAATCTCGTTTATGATTCAATTTGTTGCTC
ATCATATACCGGGAGCTAGCTTTGGGATTGCTATCATTATTATGACGCTCGTTATTCGTTCAGCAATGATTCCATTAGCT
GTTTCGCAATATCGTAGCCAAGCGAAAATGAAAAAAATGCAACCTGAATTGCAGAAGCTAAAGCAGAAATACGGTGATGT
AAGCAAAGATCTAGAAAAACAAAAACAGTATCAAAAAGAAATGTCAGAACTAATGAAATCAGGCGGTTGGAATCCACTTG
CTGGTTGCTGGCCACTATTAATACAAATGCCGATTTTCTCTGCTTTGTATTATGCGATTAGCCGAACAGAAGAGATTCGC
ACATCTACATTTTTATGGGTGAACTTAGGACATGCAGATCCTTATCATATATTACCGATTATTGCAGCGTTAACGACATT
TATTCAGATGAAAGTTTTCCAATCGAATAGTACGTCTGGAGAACAAGTACAAATGCTAAAGATGCAGCAAATTATGATGC
CCGCAATGATTCTATTTATGGGATTTGCGGCGCCATCCGGACTTGTGTTGTACTGGATAACAGGTAACTTATTTACAATG
ATGCAAACAATCGTATTAAGAAAAATAATGGAACGTGAAGAGTTACAATTACAAAAAGCTTAG

Upstream 100 bases:

>100_bases
CGTTCTGTACGTAGACAAGAATCAAGTGAAGAGAATGACGAGGTCGGTCCGTATACACCAATGTTTCGCTAAATAATTAC
GAAACATTGGAGGAATGAAC

Downstream 100 bases:

>100_bases
AGAAACACCGCTCGTGATGAGCGGTGTTTTTTTGTTAAGTCGTTAAGGAAATGTTAAGAAACCCTCATTACGATAGGCAT
TGTATACGAAAGTGTACATG

Product: OxaA-like protein precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLKSYRAVLVSLSLLLVFVLSGCSNATPIDAHSTGIWDHYFVYPISFMIQFVAHHIPGASFGIAIIIMTLVIRSAMIPLA
VSQYRSQAKMKKMQPELQKLKQKYGDVSKDLEKQKQYQKEMSELMKSGGWNPLAGCWPLLIQMPIFSALYYAISRTEEIR
TSTFLWVNLGHADPYHILPIIAALTTFIQMKVFQSNSTSGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTM
MQTIVLRKIMEREELQLQKA

Sequences:

>Translated_260_residues
MLKSYRAVLVSLSLLLVFVLSGCSNATPIDAHSTGIWDHYFVYPISFMIQFVAHHIPGASFGIAIIIMTLVIRSAMIPLA
VSQYRSQAKMKKMQPELQKLKQKYGDVSKDLEKQKQYQKEMSELMKSGGWNPLAGCWPLLIQMPIFSALYYAISRTEEIR
TSTFLWVNLGHADPYHILPIIAALTTFIQMKVFQSNSTSGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTM
MQTIVLRKIMEREELQLQKA
>Mature_260_residues
MLKSYRAVLVSLSLLLVFVLSGCSNATPIDAHSTGIWDHYFVYPISFMIQFVAHHIPGASFGIAIIIMTLVIRSAMIPLA
VSQYRSQAKMKKMQPELQKLKQKYGDVSKDLEKQKQYQKEMSELMKSGGWNPLAGCWPLLIQMPIFSALYYAISRTEEIR
TSTFLWVNLGHADPYHILPIIAALTTFIQMKVFQSNSTSGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTM
MQTIVLRKIMEREELQLQKA

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=200, Percent_Identity=39.5, Blast_Score=134, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24662345, Length=204, Percent_Identity=26.9607843137255, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21356443, Length=204, Percent_Identity=26.9607843137255, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA2_BACAN (Q81XH4)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847442.1
- RefSeq:   YP_021920.1
- RefSeq:   YP_031130.1
- IntAct:   Q81XH4
- EnsemblBacteria:   EBBACT00000013211
- EnsemblBacteria:   EBBACT00000016283
- EnsemblBacteria:   EBBACT00000024238
- GeneID:   1084727
- GeneID:   2819404
- GeneID:   2847919
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_5263
- KEGG:   bar:GBAA_5263
- KEGG:   bat:BAS4889
- TIGR:   BA_5263
- TIGR:   GBAA_5263
- GeneTree:   EBGT00050000002639
- HOGENOM:   HBG560622
- OMA:   SNAAPID
- ProtClustDB:   PRK01622
- BioCyc:   BANT260799:BAS4889-MONOMER
- BioCyc:   BANT261594:GBAA5263-MONOMER
- HAMAP:   MF_01811
- InterPro:   IPR001708
- InterPro:   IPR023060
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 29570; Mature: 29570

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17011ba4)-; HASH(0x170b9818)-; HASH(0x16eb59ac)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
7.3 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSYRAVLVSLSLLLVFVLSGCSNATPIDAHSTGIWDHYFVYPISFMIQFVAHHIPGAS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
FGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKQKYGDVSKDLEKQKQYQKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MSELMKSGGWNPLAGCWPLLIQMPIFSALYYAISRTEEIRTSTFLWVNLGHADPYHILPI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHH
IAALTTFIQMKVFQSNSTSGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTM
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHH
MQTIVLRKIMEREELQLQKA
HHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLKSYRAVLVSLSLLLVFVLSGCSNATPIDAHSTGIWDHYFVYPISFMIQFVAHHIPGAS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
FGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKQKYGDVSKDLEKQKQYQKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MSELMKSGGWNPLAGCWPLLIQMPIFSALYYAISRTEEIRTSTFLWVNLGHADPYHILPI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHH
IAALTTFIQMKVFQSNSTSGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTM
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHH
MQTIVLRKIMEREELQLQKA
HHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629