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The map label for this gene is metI [H]

Identifier: 49187844

GI number: 49187844

Start: 4739223

End: 4739894

Strand: Reverse

Name: metI [H]

Synonym: BAS4854

Alternate gene names: 49187844

Gene position: 4739894-4739223 (Counterclockwise)

Preceding gene: 49187845

Following gene: 49187843

Centisome position: 90.65

GC content: 38.24

Gene sequence:

>672_bases
TTGCACATGGATAAGTTACTCACGAATGTTGATTGGAATCAAATGTTAGAAGCAACTGGTGAAACGTTATATATGACGGC
AATCGCAGCTCTTGCCACATTTATTTTAGGACTTATTTTAGGATTGTTGCTCTTTATGACAGCGAAAGATAATTTATGGG
AAAACAAAGCGGTTAACACGGCGATTGGAGCGTTCGTAAACATTTTCCGCTCGATACCGTTCATCATTTTAATCATTTTA
TTAATCCCATTCACAAAGATTCTGCTTGGAACAATTCTTGGAGCAAGTGCAGCACTTCCAGCTTTAATTATTGGAGCAGC
ACCATTTTACGCGAGAATGGTTGAAATCGCACTTCGTGAAATTGATAAAGGTGTAATTGAAGCTTCGAAAGCGATGGGAG
CAAAAACAAGCACAATTATTTTAAAAGTATTGATTCCAGAATCGTTACCAGCATTAGTATCTGGTATTACGGTTACGACA
ATTGCTTTAGTGGGCTATACAGCAATGGCGGGAGTTGTTGGTGCTGGTGGTCTTGGAACACTTGCTTATTTAGAAGGATT
CCAACGAGGAAATAACGATGTAACAATCGTTGCGACAATTTGTGTATTACTAGTTGTATTTTTCATTCAGTGGATTGGTG
ATCGTGTAACGACTCGAATAGATAAACGATAA

Upstream 100 bases:

>100_bases
GGTTCTTACGGTAGTTTAGTTGTTCATTTAAATGGTGAGGAAACAGCGATTCAGCAAGCAATAGAGGGAATACATCAAGA
TCAAGTAGAGCTGGAGGTGA

Downstream 100 bases:

>100_bases
TAAAAAACGGGAGGATGTTTCAAATGAAAAAATTATTACTGACAGCACTTATTTCAACTTCAATTTTTGGGTTAGCTGCC
TGCGGGGGGAAAGATAACGA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MHMDKLLTNVDWNQMLEATGETLYMTAIAALATFILGLILGLLLFMTAKDNLWENKAVNTAIGAFVNIFRSIPFIILIIL
LIPFTKILLGTILGASAALPALIIGAAPFYARMVEIALREIDKGVIEASKAMGAKTSTIILKVLIPESLPALVSGITVTT
IALVGYTAMAGVVGAGGLGTLAYLEGFQRGNNDVTIVATICVLLVVFFIQWIGDRVTTRIDKR

Sequences:

>Translated_223_residues
MHMDKLLTNVDWNQMLEATGETLYMTAIAALATFILGLILGLLLFMTAKDNLWENKAVNTAIGAFVNIFRSIPFIILIIL
LIPFTKILLGTILGASAALPALIIGAAPFYARMVEIALREIDKGVIEASKAMGAKTSTIILKVLIPESLPALVSGITVTT
IALVGYTAMAGVVGAGGLGTLAYLEGFQRGNNDVTIVATICVLLVVFFIQWIGDRVTTRIDKR
>Mature_223_residues
MHMDKLLTNVDWNQMLEATGETLYMTAIAALATFILGLILGLLLFMTAKDNLWENKAVNTAIGAFVNIFRSIPFIILIIL
LIPFTKILLGTILGASAALPALIIGAAPFYARMVEIALREIDKGVIEASKAMGAKTSTIILKVLIPESLPALVSGITVTT
IALVGYTAMAGVVGAGGLGTLAYLEGFQRGNNDVTIVATICVLLVVFFIQWIGDRVTTRIDKR

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=203, Percent_Identity=47.2906403940887, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1788451, Length=199, Percent_Identity=27.1356783919598, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23866; Mature: 23866

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMDKLLTNVDWNQMLEATGETLYMTAIAALATFILGLILGLLLFMTAKDNLWENKAVNT
CCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AIGAFVNIFRSIPFIILIILLIPFTKILLGTILGASAALPALIIGAAPFYARMVEIALRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDKGVIEASKAMGAKTSTIILKVLIPESLPALVSGITVTTIALVGYTAMAGVVGAGGLGT
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAYLEGFQRGNNDVTIVATICVLLVVFFIQWIGDRVTTRIDKR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHMDKLLTNVDWNQMLEATGETLYMTAIAALATFILGLILGLLLFMTAKDNLWENKAVNT
CCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AIGAFVNIFRSIPFIILIILLIPFTKILLGTILGASAALPALIIGAAPFYARMVEIALRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDKGVIEASKAMGAKTSTIILKVLIPESLPALVSGITVTTIALVGYTAMAGVVGAGGLGT
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAYLEGFQRGNNDVTIVATICVLLVVFFIQWIGDRVTTRIDKR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]