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The map label for this gene is lytH [H]

Identifier: 49187831

GI number: 49187831

Start: 4726351

End: 4727352

Strand: Direct

Name: lytH [H]

Synonym: BAS4841

Alternate gene names: 49187831

Gene position: 4726351-4727352 (Clockwise)

Preceding gene: 49187829

Following gene: 49187835

Centisome position: 90.39

GC content: 41.72

Gene sequence:

>1002_bases
GTGAAAGGAGTCTATTTCATGCTTCGAAAAATTTCTCTTTTGCTTTCGATTTGCTTTCTTCTCCACCAAAACATCGCTTA
CGGTGAAGATAATCAGCAAAGCATATACGAAAAGCGCATGGCACTATATAAAGAAACCGAGCAATCTTCAGGCATTCCGT
GGTATTACTTAGCTGCAATGGATCAATATGAAAGAAATATACGGAGCGTAAGAAAAGATATTCCGAAAAAACCAGATGCC
ATCATTTCCCTTTATTTCAAACCAGAAATATGGGCTGGACCTGTTAACGGTAACGACACTCTCCCCCATACAATTGCTCT
ATTTGGCGGGTTAGGTTTAGATGGTGACAAAGATGGATTTGCAAATGCAAATAACGACCGTGACCTTCTGCATACAGCAG
CAACAATTTTAAAGAAACAAGGAACGTCAGAAGAACGTATCAAAATCATGCTCTGGGAATATTATAGACGTGCAAAAACA
GTTGATTTAATTACCGAATACGCCCAAATTTATAAACATTATGGACGTATTAATTTAGAAGGAAATGCGTTTCCCCTTCC
TATTCGCAGTGACCATAGCTACCGTAGTACTTTCGGCGCTGGGAGAAGTTTTGGCGGAAGAAGGGTTCATGAAGGAACCG
ATATATTCGCAGGCTATGGCGTACCAGTAAGATCCACTTGCTATGGCATTATTGAAACAAAGGGCTGGAATCGCCTTGGC
GGATGGCGCATCGGTATTCGCGACCTTCATAATAATTATCATTATTACGCTCACTTAGGCGGGTTCTCAAAAGAAATACA
GCTTGGACAAATTGTCGAGCCCGGAAAAGTAATCGGATTTGTTGGTAGCACCGGTTACGGTCCTCCCGGCACAGCTGGAA
AATTCCCGCCTCACTTACATTTCGGCATGTATAAAGACAACGGTTATACAGAATGGGCTTTCGATCCATACATGCATTTA
AGTCTTTGGGAGCGAAAAGAACGCGCAAATACAAAACGATAA

Upstream 100 bases:

>100_bases
CGTATGAAAGCGATTTGCTCAAATGAAGATTCTAAGATTTTTTCCAATCGTTCCCTATAATGAAATACTCCGTATATCCC
ACACTAAAAAGAGTGATGTT

Downstream 100 bases:

>100_bases
CCGTAGCACATTGCTACGGTTATTTTTCATTTACAACTAACTATCCGTTTTCTTTTTATTAGGTACAACAACACTTCCGC
TTCCATAATAAGTAGGCACT

Product: M24/M37 family peptidase

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAMDQYERNIRSVRKDIPKKPDA
IISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAATILKKQGTSEERIKIMLWEYYRRAKT
VDLITEYAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLG
GWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKDNGYTEWAFDPYMHL
SLWERKERANTKR

Sequences:

>Translated_333_residues
MKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAMDQYERNIRSVRKDIPKKPDA
IISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAATILKKQGTSEERIKIMLWEYYRRAKT
VDLITEYAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLG
GWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKDNGYTEWAFDPYMHL
SLWERKERANTKR
>Mature_333_residues
MKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAMDQYERNIRSVRKDIPKKPDA
IISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAATILKKQGTSEERIKIMLWEYYRRAKT
VDLITEYAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLG
GWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKDNGYTEWAFDPYMHL
SLWERKERANTKR

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 38053; Mature: 38053

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAM
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHH
DQYERNIRSVRKDIPKKPDAIISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGF
HHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCCCCCCCCHHHHHHCCCCCCCCCCCC
ANANNDRDLLHTAATILKKQGTSEERIKIMLWEYYRRAKTVDLITEYAQIYKHYGRINLE
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
GNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLG
CCEEECCCCCCCCHHHHHCCCCCCCCCEECCCCCEEEECCCCHHHHEEEEEECCCCCCCC
GWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLH
CEEEEHHHHCCCEEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCEE
FGMYKDNGYTEWAFDPYMHLSLWERKERANTKR
EEEEECCCEEEEECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAM
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHH
DQYERNIRSVRKDIPKKPDAIISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGF
HHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCCCCCCCCHHHHHHCCCCCCCCCCCC
ANANNDRDLLHTAATILKKQGTSEERIKIMLWEYYRRAKTVDLITEYAQIYKHYGRINLE
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
GNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLG
CCEEECCCCCCCCHHHHHCCCCCCCCCEECCCCCEEEECCCCHHHHEEEEEECCCCCCCC
GWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLH
CEEEEHHHHCCCEEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCEE
FGMYKDNGYTEWAFDPYMHLSLWERKERANTKR
EEEEECCCEEEEECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]