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The map label for this gene is kapD [H]

Identifier: 49187770

GI number: 49187770

Start: 4670074

End: 4670697

Strand: Reverse

Name: kapD [H]

Synonym: BAS4780

Alternate gene names: 49187770

Gene position: 4670697-4670074 (Counterclockwise)

Preceding gene: 49187772

Following gene: 49187768

Centisome position: 89.33

GC content: 37.5

Gene sequence:

>624_bases
ATGGATGAACAACGATTTTTATTTTTGGATTTTGAGTTTACGATGCCCCAGCACAGAAAAAAACCAAAAGGATTTTTCCC
GGAGATTATTGAGGTAGGACTCGTTTCGGTTGTTGGCTGTAAGGTAGAAGATACGTATTCAGCTCATGTTAGGCCGAAGA
CTTTTCCTTCTTTAACGGATCGATGTAAGAAATTTTTAGGGATTAAACAAGAAGTCGTAGATAAAGGGATTTCATTTTCA
GAACTCGTTGAAAAACTCGCAGAATATGAAAAGAGATGTAAACCGACCATTGTTACGTGGGGAAATATGGATATGAAAGT
GTTGAAGCATAATTGTGAAAAAGCAGGGGTAGATTTTCCGTTCCTAGGACAGTGCCGTGATTTATCGCTTGAGTATAAGA
AGTTTTTTGGTGAGAGAAATCAAACAGGATTGTGGAAAGCAATTGAAGCGTATGGAAAAGTAGGGACGGGTAAGCATCAT
TGTGCGCTAGATGATGCGATGACGACGTATAATATTTTTAAATTAGTAGAAAAAGATAAAGAGTATTTAGTGAAACCAGC
ACCTCCAACATTAGGCGAACTCGTTGATTTTTCAAAAGTGTTAAAGAAAGTGAGCACACAGTAA

Upstream 100 bases:

>100_bases
ACATCCAATCTGAATATTTAAAATGGAATTAGCATTCGAGCTTGTTCGTATAGGAGTGTCAAATAGAAAGGAATGACAAA
GATGATAAGGAAGGGATCGT

Downstream 100 bases:

>100_bases
CGACCAAATTGCACAGTATGTAATTTGGTCGTTTTGTTTTTTTAAAGTTTGTAGTCTTTTTTTAACTGCTCTAATGTTTC
TAGACTACGAACCGCAAAAG

Product: sporulation inhibitor KapD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTDRCKKFLGIKQEVVDKGISFS
ELVEKLAEYEKRCKPTIVTWGNMDMKVLKHNCEKAGVDFPFLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHH
CALDDAMTTYNIFKLVEKDKEYLVKPAPPTLGELVDFSKVLKKVSTQ

Sequences:

>Translated_207_residues
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTDRCKKFLGIKQEVVDKGISFS
ELVEKLAEYEKRCKPTIVTWGNMDMKVLKHNCEKAGVDFPFLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHH
CALDDAMTTYNIFKLVEKDKEYLVKPAPPTLGELVDFSKVLKKVSTQ
>Mature_207_residues
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTDRCKKFLGIKQEVVDKGISFS
ELVEKLAEYEKRCKPTIVTWGNMDMKVLKHNCEKAGVDFPFLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHH
CALDDAMTTYNIFKLVEKDKEYLVKPAPPTLGELVDFSKVLKKVSTQ

Specific function: Specifically inhibits the kinA pathway to sporulation [H]

COG id: COG5018

COG function: function code R; Inhibitor of the KinA pathway to sporulation, predicted exonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI31543184, Length=176, Percent_Identity=30.6818181818182, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: NA

Molecular weight: Translated: 23755; Mature: 23755

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTD
CCCCEEEEEEEEECCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
RCKKFLGIKQEVVDKGISFSELVEKLAEYEKRCKPTIVTWGNMDMKVLKHNCEKAGVDFP
HHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCC
FLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHHCALDDAMTTYNIFKLVEKDK
CCCCHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EYLVKPAPPTLGELVDFSKVLKKVSTQ
HHEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTD
CCCCEEEEEEEEECCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
RCKKFLGIKQEVVDKGISFSELVEKLAEYEKRCKPTIVTWGNMDMKVLKHNCEKAGVDFP
HHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCC
FLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHHCALDDAMTTYNIFKLVEKDK
CCCCHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EYLVKPAPPTLGELVDFSKVLKKVSTQ
HHEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]