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The map label for this gene is moaC

Identifier: 49187612

GI number: 49187612

Start: 4515703

End: 4516188

Strand: Direct

Name: moaC

Synonym: BAS4619

Alternate gene names: 49187612

Gene position: 4515703-4516188 (Clockwise)

Preceding gene: 49187604

Following gene: 49187620

Centisome position: 86.36

GC content: 38.07

Gene sequence:

>486_bases
ATGTCTTCATTCACACACTTTAATGACCAAGGACGCGCGAAGATGGTTGATATAAGCGACAAAAAAGCAACCGTTCGAAC
AGCAATTGCGTGCTCTAGCATTGTCGTTACGAAAGAAATTTACGATAAAATCTCTCATAATGAAATCGGGAAAGGTGACG
TATTAGCAGTTGCACAAATCGCTGGTATTATGGCTGCGAAACGCACTTCTGATATTATCCCAATGTGTCATCCTTTATTA
TTAAAAGGTGTTGACGTTTCTTTCGATTGGAAACAATCCGATGAACAATATCGATTACTTATTGAAGTAAAAGTTAAAAC
AGAAGGTAGTACCGGTGTTGAAATGGAAGCTTTAACAGCTGCTTCCGCTACTGCCCTTACTGTGTATGATATGTGTAAAG
CTGTTGATAAAGGTATGATTATTGGCGAAACGTACTTACTTGAAAAAACAGGTGGAAAAAGTGGAGATTATACGAGAAAG
TCTTGA

Upstream 100 bases:

>100_bases
ATTCGTTTTTCTACCATCGTTTCTCACCCCATATTTGCAATTTTTTTTATCTCGATTAAACTTTATATATTGAATAAAAA
TTACTTCAAGGAGGAATTCC

Downstream 100 bases:

>100_bases
TCTTCTCTCTGTTGAACCTAAAGGGTTTCTCTTTAGGTTCAACCTATGTATCTTGTATATAAACGTTTTGCTACATTTAT
ATCATTCGTCCCATGAATAA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSSFTHFNDQGRAKMVDISDKKATVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLL
LKGVDVSFDWKQSDEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRK
S

Sequences:

>Translated_161_residues
MSSFTHFNDQGRAKMVDISDKKATVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLL
LKGVDVSFDWKQSDEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRK
S
>Mature_160_residues
SSFTHFNDQGRAKMVDISDKKATVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLLL
KGVDVSFDWKQSDEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRKS

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=157, Percent_Identity=53.5031847133758, Blast_Score=158, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=47.0198675496689, Blast_Score=142, Evalue=8e-35,
Organism=Drosophila melanogaster, GI28574490, Length=159, Percent_Identity=48.4276729559748, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28574492, Length=146, Percent_Identity=48.6301369863014, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_BACAA (C3PBI3)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868999.1
- ProteinModelPortal:   C3PBI3
- SMR:   C3PBI3
- EnsemblBacteria:   EBBACT00000124738
- GeneID:   7851295
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4985
- GeneTree:   EBGT00050000001026
- ProtClustDB:   PRK09364
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17499; Mature: 17368

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: ACT_SITE 130-130

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFTHFNDQGRAKMVDISDKKATVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQI
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEHHHHHHHHCCCCCCCCCHHHHHHH
AGIMAAKRTSDIIPMCHPLLLKGVDVSFDWKQSDEQYRLLIEVKVKTEGSTGVEMEALTA
HHHHHHHCCCCCCHHHHHHHHCCCCCEECCCCCCCEEEEEEEEEEEECCCCCCEEEEHHH
ASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRKS
CCCHHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SSFTHFNDQGRAKMVDISDKKATVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQI
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEHHHHHHHHCCCCCCCCCHHHHHHH
AGIMAAKRTSDIIPMCHPLLLKGVDVSFDWKQSDEQYRLLIEVKVKTEGSTGVEMEALTA
HHHHHHHCCCCCCHHHHHHHHCCCCCEECCCCCCCEEEEEEEEEEEECCCCCCEEEEHHH
ASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRKS
CCCHHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA