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The map label for this gene is ycbL [H]

Identifier: 49187559

GI number: 49187559

Start: 4469680

End: 4470381

Strand: Reverse

Name: ycbL [H]

Synonym: BAS4565

Alternate gene names: 49187559

Gene position: 4470381-4469680 (Counterclockwise)

Preceding gene: 49187560

Following gene: 49187558

Centisome position: 85.5

GC content: 34.33

Gene sequence:

>702_bases
GTGGTGAGTAAATTGAAAAGAATTTTACTAATAGAAGATGAAGTAAGCATTGCAGAATTACAGCGAGATTATTTAGAAAT
TAATGATTTTCAAGTTGATGTAGAACATTCAGGAGAAACAGGTTTACAAATGGCCCTGCAAGAAGACTACGATTTAATTA
TTTTAGATATTATGCTTCCGAAAATGAATGGATTTGAAATTTGTAAGCAAATTCGAGCTATAAAAGATATTCCGATTCTA
CTTGTTTCAGCAAAAAAAGAAGATATAGATAAAATTCGCGGGCTCGGATTAGGAGCGGATGATTATATAACGAAACCGTT
TAGCCCGAGTGAGCTAGTAGCAAGAGTAAAAGCCCATATTTCTCGTTATGAAAGATTATTAGGAAATGTAAGTAAGCAAC
GCGATACGCTATATATTCACGGAATCTCTATTGATCAAAGGGCGAGGAAAGTTTTTATAAACAATGAAGAAATCGCCTTT
ACAACGAAAGAATTTGATTTATTAACATTCTTTGTCACAAACCCAAACCAAGTATTAAATAAAGAACAGTTATTTGAACG
CATTTGGGGATTAGACTCCGCTGGTGATTTAGCAACTGTTGTCGTTCATATTAGAAAGTTACGTGAAAAAATTGAAAGAG
ATCCTGCTCACCCGCAATATATTGAAACAGTGTGGGGGGCTGGTTATCGTTTTAATGTGTAG

Upstream 100 bases:

>100_bases
GCGAAGCAAATTATTGAAGAACATGGCGGAAATATTTGGGCGGAAAGCGAGCTTGGGGAAGGCACAAGCATTTTCTTCTC
ATTGGAAAAAGTAGAGAAAT

Downstream 100 bases:

>100_bases
GGAACCTGTCAAAGTTTTGGCAGGTTTTTTTTGTATGTGATCAAAAGGGGAGGATAGGTAATTTATGTTAAACTATAAAG
AGAGATAAAAACATAGGAGA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MVSKLKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNGFEICKQIRAIKDIPIL
LVSAKKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHISRYERLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAF
TTKEFDLLTFFVTNPNQVLNKEQLFERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV

Sequences:

>Translated_233_residues
MVSKLKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNGFEICKQIRAIKDIPIL
LVSAKKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHISRYERLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAF
TTKEFDLLTFFVTNPNQVLNKEQLFERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV
>Mature_233_residues
MVSKLKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNGFEICKQIRAIKDIPIL
LVSAKKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHISRYERLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAF
TTKEFDLLTFFVTNPNQVLNKEQLFERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.6828193832599, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=39.6551724137931, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=38.2222222222222, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=36.8421052631579, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=36.0869565217391, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=33.7719298245614, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.5789473684211, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=33.0472103004292, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=35.8407079646018, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=29.8245614035088, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.0175438596491, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=29.0178571428571, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=27.9475982532751, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=27.6785714285714, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26858; Mature: 26858

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSKLKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLP
CCCHHCEEEEEECCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECC
KMNGFEICKQIRAIKDIPILLVSAKKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHI
CCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHH
SRYERLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAFTTKEFDLLTFFVTNPNQVLN
HHHHHHHHCCCCCCCEEEEEECCHHHHHHEEEECCCEEEEEECCEEEEEEEEECCHHHCC
KEQLFERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECC
>Mature Secondary Structure
MVSKLKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLP
CCCHHCEEEEEECCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECC
KMNGFEICKQIRAIKDIPILLVSAKKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHI
CCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHH
SRYERLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAFTTKEFDLLTFFVTNPNQVLN
HHHHHHHHCCCCCCCEEEEEECCHHHHHHEEEECCCEEEEEECCEEEEEEEEECCHHHCC
KEQLFERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]