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The map label for this gene is nrdR

Identifier: 49187471

GI number: 49187471

Start: 4388133

End: 4388594

Strand: Reverse

Name: nrdR

Synonym: BAS4476

Alternate gene names: 49187471

Gene position: 4388594-4388133 (Counterclockwise)

Preceding gene: 49187472

Following gene: 49187470

Centisome position: 83.93

GC content: 36.8

Gene sequence:

>462_bases
TTGCGTTGTCCATCCTGTTCTCATAATGGTACAAGAGTGTTAGATTCGCGTCCGGTAGACGAGGGGCGCTCTATTCGAAG
AAGGAGAGAGTGTGAAAGCTGTTTAAGCCGCTTTACGACATTTGAAAGAGTGGAAGAGTCACCTCTTATCGTTGTAAAAA
AAGAAGGAACACGAGAAGAGTTTAATAAAGAAAAGATTTTACGTGGCTTAATTAAAGCGTGCGAAAAAAGGCCAGTATCT
TTAAGACAATTAGAAGAAGTAACTCAAAGCGTGGAACGTGAACTTCGTAATTTAGGTATATCAGAAGTGAAAAGTGATAT
GATTGGTGAAATTGTTATGGAAGAACTACGTGATATCGATGATGTTGCTTACGTGCGTTTTGCTTCTGTATATCGCCAAT
TTAAAGATTTAAATGTATTTATTGAAGAATTAAAAGATATACTGCAAAAAGAAAGAGAGTAG

Upstream 100 bases:

>100_bases
TGGTAAGAGAGTTAAAATGAGTTATATAATAATGTATATATATTGTCAGATGAAGTAAGTAGAGAAAAAATAAAGAGTAT
AGTGTAAAGGAGTGAATATA

Downstream 100 bases:

>100_bases
CATCTGTATTGTATTCTCTTTACATACCGTAAGTAATGAGATAAGAGAGCTAGAAGCGAAAGCTAATAGCTCTTTTTCGC
TAAGAAATTATATAGTGAAG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREEFNKEKILRGLIKACEKRPVS
LRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE

Sequences:

>Translated_153_residues
MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREEFNKEKILRGLIKACEKRPVS
LRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE
>Mature_153_residues
MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREEFNKEKILRGLIKACEKRPVS
LRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=50.6944444444444, Blast_Score=137, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_BACAA (C3PAG9)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868859.1
- EnsemblBacteria:   EBBACT00000129968
- GeneID:   7848354
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4835
- GeneTree:   EBGT00050000001207
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18024; Mature: 18024

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHH
FNKEKILRGLIKACEKRPVSLRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDID
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DVAYVRFASVYRQFKDLNVFIEELKDILQKERE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHH
FNKEKILRGLIKACEKRPVSLRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDID
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DVAYVRFASVYRQFKDLNVFIEELKDILQKERE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA