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The map label for this gene is asnC

Identifier: 49187449

GI number: 49187449

Start: 4365135

End: 4366526

Strand: Reverse

Name: asnC

Synonym: BAS4454

Alternate gene names: 49187449

Gene position: 4366526-4365135 (Counterclockwise)

Preceding gene: 49187450

Following gene: 49187445

Centisome position: 83.51

GC content: 40.88

Gene sequence:

>1392_bases
ATGGAAAACACATTAGTAAAAAGTCTGTATAGAGATACAGATAAATACGCAGGTCAAACAGTACAAGTATCAGGGTGGAT
TCGTAACTTACGTGATTCAAAAGCATTTGGTTTCATCGAATTAAACGACGGTAGCTTCTTCAAAAGCGTTCAAATCGTTT
TCGATACAGAATTAGATAACTTCAAAGAAATTGCAAAACTTCCACTTAGCTCTTCAGTTAAAGTAGAAGGTAAAGTAATT
GCAACGCCTGGAGCGAAGCAACCATTTGAAATTAAAGCAGAAAAAATTGATATCGAGGGCTTATCAGATTCTGATTACCC
ACTTCAAAAGAAACGTCATACGTTTGAATACTTACGTACAATCGCTCACTTACGTCCAAGAACAAATGCATTCTCTGCAA
CGTTCCGCGTACGTTCTATCGCAGCATTTGCGATTCACCAATTCTTCCAAGAGCGTGGATTCGTACATGTTCACACACCA
ATCATCACTGGTAGTGATACAGAAGGTGCGGGCGAAATGTTCCGCGTAACAACGCAAGATTTAAACAACGTACCAAAAGG
CGAAGACGGACAAGTTGATGAATCAAAAGACTTCTTCGGCAAAGAAACAAACTTAACAGTAAGTGGACAGCTGAACGCTG
AAGCTTATGCATTAGCATTCCGTGATGTATACACATTCGGACCTACATTCCGTGCAGAAAACTCAAACACAACTCGCCAC
GCAGCTGAGTTCTGGATGGTTGAGCCTGAGATTGCATTTGCTGAACTAGGTGACGTAATGAACCTTACAGAAGATATGCT
GAAATATGCAATGAAATACGTATTAGAGCATGCACCAGAAGAAATGGAATTCTTCAACAGCTTCGTTGATAAAACAGTTC
TAGAGCGCATGAACAACGTAATCAACTCTGACTTCGGTCGCATCACTTATACAGAAGCAATTAAAGTACTTCAAGAGTCA
GGTGCTGACTTCAAATACCCAGTAGAATGGGGTATTGACTTACAAACAGAGCACGAAAGATACTTATCAGAAGAAATCTT
CAAACGCCCTGTATTCGTAACTGACTATCCGAAAGACATTAAAGCATTCTACATGCGCTTAAATGACGACGGTAAAACAG
TAGCTGCTACTGACCTTCTAGTTCCTGGCATCGGCGAATTAATCGGCGGAAGCCAACGTGAAGAAAGAATGGACGTTTTA
GTAGACAGAATTAAAGAACTAGGCATGAACGAAGAGGACTACTGGTGGTACTTAGAACTTAGAAAATACGGCGGTACAAA
ACACGCTGGATTCGGTCTAGGTTTCGAGCGCTTCCTAATGTATATCACTGGCATGGCTAACATCCGTGACGTAATTCCAT
TCCCAAGAACTCCAGGTTCTTCTGAATTCTAA

Upstream 100 bases:

>100_bases
TTATGACAAATTGGGTGGTACCGCGAAGTTTAACCTTTCGTCCCTTTATGGATGAAAGGTTTTTTTGTATTTAAATATAT
CAGCAAAGGAGAACTTCACT

Downstream 100 bases:

>100_bases
AATATGAAAAAGCGAGAGGGTTTTCTCTCGCTTTTTTATTTTGTATAGTTTACTACCTCGTAGCAAAAAAGTAACGCGAA
GGGGTGAATATAAATGAGTA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MENTLVKSLYRDTDKYAGQTVQVSGWIRNLRDSKAFGFIELNDGSFFKSVQIVFDTELDNFKEIAKLPLSSSVKVEGKVI
ATPGAKQPFEIKAEKIDIEGLSDSDYPLQKKRHTFEYLRTIAHLRPRTNAFSATFRVRSIAAFAIHQFFQERGFVHVHTP
IITGSDTEGAGEMFRVTTQDLNNVPKGEDGQVDESKDFFGKETNLTVSGQLNAEAYALAFRDVYTFGPTFRAENSNTTRH
AAEFWMVEPEIAFAELGDVMNLTEDMLKYAMKYVLEHAPEEMEFFNSFVDKTVLERMNNVINSDFGRITYTEAIKVLQES
GADFKYPVEWGIDLQTEHERYLSEEIFKRPVFVTDYPKDIKAFYMRLNDDGKTVAATDLLVPGIGELIGGSQREERMDVL
VDRIKELGMNEEDYWWYLELRKYGGTKHAGFGLGFERFLMYITGMANIRDVIPFPRTPGSSEF

Sequences:

>Translated_463_residues
MENTLVKSLYRDTDKYAGQTVQVSGWIRNLRDSKAFGFIELNDGSFFKSVQIVFDTELDNFKEIAKLPLSSSVKVEGKVI
ATPGAKQPFEIKAEKIDIEGLSDSDYPLQKKRHTFEYLRTIAHLRPRTNAFSATFRVRSIAAFAIHQFFQERGFVHVHTP
IITGSDTEGAGEMFRVTTQDLNNVPKGEDGQVDESKDFFGKETNLTVSGQLNAEAYALAFRDVYTFGPTFRAENSNTTRH
AAEFWMVEPEIAFAELGDVMNLTEDMLKYAMKYVLEHAPEEMEFFNSFVDKTVLERMNNVINSDFGRITYTEAIKVLQES
GADFKYPVEWGIDLQTEHERYLSEEIFKRPVFVTDYPKDIKAFYMRLNDDGKTVAATDLLVPGIGELIGGSQREERMDVL
VDRIKELGMNEEDYWWYLELRKYGGTKHAGFGLGFERFLMYITGMANIRDVIPFPRTPGSSEF
>Mature_463_residues
MENTLVKSLYRDTDKYAGQTVQVSGWIRNLRDSKAFGFIELNDGSFFKSVQIVFDTELDNFKEIAKLPLSSSVKVEGKVI
ATPGAKQPFEIKAEKIDIEGLSDSDYPLQKKRHTFEYLRTIAHLRPRTNAFSATFRVRSIAAFAIHQFFQERGFVHVHTP
IITGSDTEGAGEMFRVTTQDLNNVPKGEDGQVDESKDFFGKETNLTVSGQLNAEAYALAFRDVYTFGPTFRAENSNTTRH
AAEFWMVEPEIAFAELGDVMNLTEDMLKYAMKYVLEHAPEEMEFFNSFVDKTVLERMNNVINSDFGRITYTEAIKVLQES
GADFKYPVEWGIDLQTEHERYLSEEIFKRPVFVTDYPKDIKAFYMRLNDDGKTVAATDLLVPGIGELIGGSQREERMDVL
VDRIKELGMNEEDYWWYLELRKYGGTKHAGFGLGFERFLMYITGMANIRDVIPFPRTPGSSEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=450, Percent_Identity=46.2222222222222, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI4758762, Length=466, Percent_Identity=29.6137339055794, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI45439306, Length=341, Percent_Identity=28.4457478005865, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1787161, Length=447, Percent_Identity=59.0604026845638, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI1790571, Length=377, Percent_Identity=28.1167108753316, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789256, Length=374, Percent_Identity=26.2032085561497, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=35.7798165137615, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17556372, Length=428, Percent_Identity=32.4766355140187, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=460, Percent_Identity=30, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=349, Percent_Identity=28.6532951289398, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=484, Percent_Identity=39.4628099173554, Blast_Score=328, Evalue=8e-91,
Organism=Saccharomyces cerevisiae, GI6321807, Length=474, Percent_Identity=29.746835443038, Blast_Score=213, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6323011, Length=346, Percent_Identity=29.1907514450867, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19922416, Length=458, Percent_Identity=36.0262008733624, Blast_Score=274, Evalue=9e-74,
Organism=Drosophila melanogaster, GI19921528, Length=454, Percent_Identity=28.8546255506608, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI17136276, Length=480, Percent_Identity=25.2083333333333, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_BACAN (Q81L32)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847005.1
- RefSeq:   YP_021447.1
- RefSeq:   YP_030701.1
- ProteinModelPortal:   Q81L32
- SMR:   Q81L32
- IntAct:   Q81L32
- EnsemblBacteria:   EBBACT00000011792
- EnsemblBacteria:   EBBACT00000014618
- EnsemblBacteria:   EBBACT00000021099
- GeneID:   1083928
- GeneID:   2815787
- GeneID:   2851600
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_4802
- KEGG:   bar:GBAA_4802
- KEGG:   bat:BAS4454
- TIGR:   BA_4802
- TIGR:   GBAA_4802
- GeneTree:   EBGT00050000000858
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   BANT260799:BAS4454-MONOMER
- BioCyc:   BANT261594:GBAA4802-MONOMER
- BRENDA:   6.1.1.22
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52926; Mature: 52926

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTLVKSLYRDTDKYAGQTVQVSGWIRNLRDSKAFGFIELNDGSFFKSVQIVFDTELDN
CCHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEECCCHH
FKEIAKLPLSSSVKVEGKVIATPGAKQPFEIKAEKIDIEGLSDSDYPLQKKRHTFEYLRT
HHHHHHCCCCCCEEECCEEEECCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
IAHLRPRTNAFSATFRVRSIAAFAIHQFFQERGFVHVHTPIITGSDTEGAGEMFRVTTQD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCCCEEEEEHHH
LNNVPKGEDGQVDESKDFFGKETNLTVSGQLNAEAYALAFRDVYTFGPTFRAENSNTTRH
HCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCEEEEEHHHHHHCCCCEECCCCCCHHH
AAEFWMVEPEIAFAELGDVMNLTEDMLKYAMKYVLEHAPEEMEFFNSFVDKTVLERMNNV
HHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
INSDFGRITYTEAIKVLQESGADFKYPVEWGIDLQTEHERYLSEEIFKRPVFVTDYPKDI
HCCCCCCEEHHHHHHHHHHCCCCEEECCEECCCCCHHHHHHHHHHHHHCCCEEECCCHHH
KAFYMRLNDDGKTVAATDLLVPGIGELIGGSQREERMDVLVDRIKELGMNEEDYWWYLEL
EEEEEEECCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
RKYGGTKHAGFGLGFERFLMYITGMANIRDVIPFPRTPGSSEF
EECCCCCCCCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MENTLVKSLYRDTDKYAGQTVQVSGWIRNLRDSKAFGFIELNDGSFFKSVQIVFDTELDN
CCHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEECCCHH
FKEIAKLPLSSSVKVEGKVIATPGAKQPFEIKAEKIDIEGLSDSDYPLQKKRHTFEYLRT
HHHHHHCCCCCCEEECCEEEECCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
IAHLRPRTNAFSATFRVRSIAAFAIHQFFQERGFVHVHTPIITGSDTEGAGEMFRVTTQD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCCCEEEEEHHH
LNNVPKGEDGQVDESKDFFGKETNLTVSGQLNAEAYALAFRDVYTFGPTFRAENSNTTRH
HCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCEEEEEHHHHHHCCCCEECCCCCCHHH
AAEFWMVEPEIAFAELGDVMNLTEDMLKYAMKYVLEHAPEEMEFFNSFVDKTVLERMNNV
HHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
INSDFGRITYTEAIKVLQESGADFKYPVEWGIDLQTEHERYLSEEIFKRPVFVTDYPKDI
HCCCCCCEEHHHHHHHHHHCCCCEEECCEECCCCCHHHHHHHHHHHHHCCCEEECCCHHH
KAFYMRLNDDGKTVAATDLLVPGIGELIGGSQREERMDVLVDRIKELGMNEEDYWWYLEL
EEEEEEECCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
RKYGGTKHAGFGLGFERFLMYITGMANIRDVIPFPRTPGSSEF
EECCCCCCCCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629