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The map label for this gene is isdG

Identifier: 49187432

GI number: 49187432

Start: 4347250

End: 4347573

Strand: Direct

Name: isdG

Synonym: BAS4437

Alternate gene names: 49187432

Gene position: 4347250-4347573 (Clockwise)

Preceding gene: 49187429

Following gene: 49187446

Centisome position: 83.14

GC content: 35.19

Gene sequence:

>324_bases
ATGATTATTGTTACAAATACAGCTAAAATTACAAAGGGTAATGGACATAAATTAATTGATCGTTTTAATAAAGTAGGTCA
AGTGGAAACAATGCCAGGCTTTTTAGGATTAGAAGTTCTTCTAACGCAAAATACAGTTGATTATGATGAAGTAACAATTA
GTACACGCTGGAATGCAAAAGAAGATTTCCAAGGTTGGACGAAGAGCCCAGCATTTAAAGCTGCTCACTCCCATCAAGGC
GGAATGCCAGATTATATTCTTGATAATAAAATCTCTTACTATGATGTAAAAGTTGTACGTATGCCAATGGCTGCAGCACA
GTAA

Upstream 100 bases:

>100_bases
CATAATTTAAGATTACCGTTGACAATGATAATGATTTTCATTATCATTTAATGTATATGAATTCTCGAAAATAAAGGCTA
CACTTATAGGAGGAATAAAC

Downstream 100 bases:

>100_bases
ACATATTTCTTTTTTAAAGTATAGAATAGGAGAAACGTTACCACTTCTCCTATTCTATACTTTTTTTACTGTCTTTTTAC
TAGTTTCGCATGTACGACTA

Product: heme-degrading monooxygenase IsdG

Products: NA

Alternate protein names: Heme oxygenase; Iron-regulated surface determinant isdG; Iron-responsive surface determinant isdG

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MIIVTNTAKITKGNGHKLIDRFNKVGQVETMPGFLGLEVLLTQNTVDYDEVTISTRWNAKEDFQGWTKSPAFKAAHSHQG
GMPDYILDNKISYYDVKVVRMPMAAAQ

Sequences:

>Translated_107_residues
MIIVTNTAKITKGNGHKLIDRFNKVGQVETMPGFLGLEVLLTQNTVDYDEVTISTRWNAKEDFQGWTKSPAFKAAHSHQG
GMPDYILDNKISYYDVKVVRMPMAAAQ
>Mature_107_residues
MIIVTNTAKITKGNGHKLIDRFNKVGQVETMPGFLGLEVLLTQNTVDYDEVTISTRWNAKEDFQGWTKSPAFKAAHSHQG
GMPDYILDNKISYYDVKVVRMPMAAAQ

Specific function: Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subseque

COG id: COG2329

COG function: function code R; Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase isdG subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISDG_BACAA (C3PAD1)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868821.1
- ProteinModelPortal:   C3PAD1
- EnsemblBacteria:   EBBACT00000126061
- GeneID:   7852114
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4795
- GeneTree:   EBGT00050000000079
- ProtClustDB:   PRK13314
- GO:   GO:0005737
- HAMAP:   MF_01272
- InterPro:   IPR007138
- InterPro:   IPR011008

Pfam domain/function: PF03992 ABM; SSF54909 Dimer_A_B_barrel

EC number: =1.14.99.3

Molecular weight: Translated: 12004; Mature: 12004

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVTNTAKITKGNGHKLIDRFNKVGQVETMPGFLGLEVLLTQNTVDYDEVTISTRWNAK
CEEECCCCEEECCCCHHHHHHHHHCCCEECCCCCCCEEEEEECCCCCCCEEEEEECCCCC
EDFQGWTKSPAFKAAHSHQGGMPDYILDNKISYYDVKVVRMPMAAAQ
HHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEECCCCCC
>Mature Secondary Structure
MIIVTNTAKITKGNGHKLIDRFNKVGQVETMPGFLGLEVLLTQNTVDYDEVTISTRWNAK
CEEECCCCEEECCCCHHHHHHHHHCCCEECCCCCCCEEEEEECCCCCCCEEEEEECCCCC
EDFQGWTKSPAFKAAHSHQGGMPDYILDNKISYYDVKVVRMPMAAAQ
HHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA