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The map label for this gene is sdhB [H]

Identifier: 49187407

GI number: 49187407

Start: 4320867

End: 4321628

Strand: Reverse

Name: sdhB [H]

Synonym: BAS4412

Alternate gene names: 49187407

Gene position: 4321628-4320867 (Counterclockwise)

Preceding gene: 49187408

Following gene: 49187406

Centisome position: 82.65

GC content: 41.08

Gene sequence:

>762_bases
ATGTCTGAGAAAACAATCCGCCTCATCATTACGAGACAAGACGGACCAGACGCGCAAGCGTTTGATCAAGAGTTTGAAAT
TCCTTATCGTCCGAATATGAATATTATTTCGGCGCTTATGGAAATTCGCCGTAATCCTGTTGATTCAAAAGGAAACCAAA
CGACTCCGATTGCGTGGGATATGAACTGTTTAGAGGAAGTGTGTGGTGCATGTTCGATGGTGATTAACGGAAAACCACGT
CAATCATGTACAGCACTTATCGATCAATTAGAGCAACCAATTCGCTTAAAACCGATGAAGACATTCCCGGTTGTTCGTGA
CTTACAAGTTGACCGTAGTCGCATGTTTAATGCTCTAAAACGTGTTAAAGCTTGGATTCCAATTGATGGTACGTATGACT
TAGGACCAGGGCCAAGAATGCCAGAGAAGAAACGTCAATGGGCTTATGAGCTTTCAAAATGTATGACATGTGGTGTTTGC
TTAGAATCATGTCCAAACGTAAATAGTAAATCTGACTTTATTGGACCAGCACCGTTATCACAAGCTCGTTTATTCAACTC
ACATCCAACGGGTGAAATGCATAAAGCAGATCGCTTACGTGCAATTATGGGTGATGGAGGACTTGCAAACTGTGGTAACT
CTCAAAACTGTGTGCAATCATGTCCAAAGGGTATTCCATTAACAACTTCAATTGCGGCGTTAAACCGTGATACAACAATT
CAATCGTTCAAAGATTTCTTTGGTAGCGACAATAACTATTAA

Upstream 100 bases:

>100_bases
TATGAAGATGTGGATATTTCATTAATTAAACCACGTAAACGTGATTATTCTTCAAAACACGATGTAGCTGCTAAGGGTGA
AGAGAAGGGGGATAAACAAC

Downstream 100 bases:

>100_bases
TAAATATTGCCTCTTCATATCGAAGAGGCAATATTTATAACTTTATTTTTCTGTTTATTCTGTTTATTCTTTTTATTCGA
AGGTGAAAAGGAGAGGGAAC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSEKTIRLIITRQDGPDAQAFDQEFEIPYRPNMNIISALMEIRRNPVDSKGNQTTPIAWDMNCLEEVCGACSMVINGKPR
QSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFNALKRVKAWIPIDGTYDLGPGPRMPEKKRQWAYELSKCMTCGVC
LESCPNVNSKSDFIGPAPLSQARLFNSHPTGEMHKADRLRAIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTTI
QSFKDFFGSDNNY

Sequences:

>Translated_253_residues
MSEKTIRLIITRQDGPDAQAFDQEFEIPYRPNMNIISALMEIRRNPVDSKGNQTTPIAWDMNCLEEVCGACSMVINGKPR
QSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFNALKRVKAWIPIDGTYDLGPGPRMPEKKRQWAYELSKCMTCGVC
LESCPNVNSKSDFIGPAPLSQARLFNSHPTGEMHKADRLRAIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTTI
QSFKDFFGSDNNY
>Mature_252_residues
SEKTIRLIITRQDGPDAQAFDQEFEIPYRPNMNIISALMEIRRNPVDSKGNQTTPIAWDMNCLEEVCGACSMVINGKPRQ
SCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFNALKRVKAWIPIDGTYDLGPGPRMPEKKRQWAYELSKCMTCGVCL
ESCPNVNSKSDFIGPAPLSQARLFNSHPTGEMHKADRLRAIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTTIQ
SFKDFFGSDNNY

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=238, Percent_Identity=27.3109243697479, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=25.4464285714286, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1786943, Length=229, Percent_Identity=28.3842794759825, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17533915, Length=226, Percent_Identity=25.2212389380531, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322987, Length=247, Percent_Identity=26.7206477732794, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643156, Length=228, Percent_Identity=26.7543859649123, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137106, Length=230, Percent_Identity=24.3478260869565, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28251; Mature: 28120

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKTIRLIITRQDGPDAQAFDQEFEIPYRPNMNIISALMEIRRNPVDSKGNQTTPIAWD
CCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEC
MNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFNALK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RVKAWIPIDGTYDLGPGPRMPEKKRQWAYELSKCMTCGVCLESCPNVNSKSDFIGPAPLS
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
QARLFNSHPTGEMHKADRLRAIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTTI
HHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCHHH
QSFKDFFGSDNNY
HHHHHHCCCCCCC
>Mature Secondary Structure 
SEKTIRLIITRQDGPDAQAFDQEFEIPYRPNMNIISALMEIRRNPVDSKGNQTTPIAWD
CCCEEEEEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEC
MNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFPVVRDLQVDRSRMFNALK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RVKAWIPIDGTYDLGPGPRMPEKKRQWAYELSKCMTCGVCLESCPNVNSKSDFIGPAPLS
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
QARLFNSHPTGEMHKADRLRAIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTTI
HHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCHHH
QSFKDFFGSDNNY
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]