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The map label for this gene is lytS [H]

Identifier: 49187390

GI number: 49187390

Start: 4308055

End: 4308576

Strand: Direct

Name: lytS [H]

Synonym: BAS4395

Alternate gene names: 49187390

Gene position: 4308055-4308576 (Clockwise)

Preceding gene: 49187389

Following gene: 49187391

Centisome position: 82.39

GC content: 30.65

Gene sequence:

>522_bases
ATGTTAACTTATGAAGCATTTGCTGTATTAATAACTATACTTGTCTTAGCTCCAATTTTTGGAGCTATTATTTTATTATG
TTTATTTATTTTTGAAAAACGAATCGACTTACTAGAAAGTGAGAAGAAAAAAATAGCACTAGAAAGAGAGTTGCAACAGT
CTTTATATCATCAACTCACTCAACAAATTCAGCCTCATTTTTTATTCAATACATTAAATACAATTTTAAGCTTAGCCCGT
TTGCAAAGAACAGATGAAGTTGTCCGATCGCTCGAGATCTTTTCTCTATTTTTAAAAGGAAAATATAAAACAACAGATTT
GTTAATTCCTATTTCTGAAGAACTAGCGTATACAAATTATTATATTGAGATTCAAAAAATGCGGTTTCGCTCGAGGCTTT
CAGTAAGCATTAATTCTTCTGAAGATTTACACAATGCCCATATTCCCCCTTTCGTTATTCAAACGTTAGTGGAGAATTCC
TTTAAACATGGTCTTGAAAAAAAGCTGGTCAAGCAATTTTAA

Upstream 100 bases:

>100_bases
AGATCATAAAGTAGCCTGTCATATTATTTAATGCGAGTCTGAATAATAGAAATATTTACAACGCTTTAGTATAATAATAA
AAAACAAGATTGAGGTATGT

Downstream 100 bases:

>100_bases
ATATTCATTTATACAATACAAATAACCGAATTACACTTCTAGTATCCGACAACGGTACTCAAAATGAACCATTTACTTCC
CATACAGAAGAAAGCGGATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLTQQIQPHFLFNTLNTILSLAR
LQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNYYIEIQKMRFRSRLSVSINSSEDLHNAHIPPFVIQTLVENS
FKHGLEKKLVKQF

Sequences:

>Translated_173_residues
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLTQQIQPHFLFNTLNTILSLAR
LQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNYYIEIQKMRFRSRLSVSINSSEDLHNAHIPPFVIQTLVENS
FKHGLEKKLVKQF
>Mature_173_residues
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLTQQIQPHFLFNTLNTILSLAR
LQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNYYIEIQKMRFRSRLSVSINSSEDLHNAHIPPFVIQTLVENS
FKHGLEKKLVKQF

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=119, Percent_Identity=35.2941176470588, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1788723, Length=111, Percent_Identity=39.6396396396396, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 20229; Mature: 20229

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQIQPHFLFNTLNTILSLARLQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNY
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHH
YIEIQKMRFRSRLSVSINSSEDLHNAHIPPFVIQTLVENSFKHGLEKKLVKQF
HHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQIQPHFLFNTLNTILSLARLQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNY
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHH
YIEIQKMRFRSRLSVSINSSEDLHNAHIPPFVIQTLVENSFKHGLEKKLVKQF
HHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]