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The map label for this gene is minD [H]

Identifier: 49187341

GI number: 49187341

Start: 4255811

End: 4256608

Strand: Reverse

Name: minD [H]

Synonym: BAS4346

Alternate gene names: 49187341

Gene position: 4256608-4255811 (Counterclockwise)

Preceding gene: 49187342

Following gene: 49187340

Centisome position: 81.41

GC content: 40.23

Gene sequence:

>798_bases
GTGGGAGAGGCAATAGTAATTACATCTGGAAAAGGCGGTGTAGGTAAAACTACAACGTCTGCGAACATTGGGACAGCCTT
AGCGTTATCTGGAAAGAAAGTGTGTTTAATTGACACAGATATCGGTCTTCGAAACTTAGACGTAGTAATGGGGCTGGAAA
ATCGTATTGTATTTGATCTTGTTGATGTCGTTGAAGGGCGTTGCCGTTTACCTCAGGCTCTTATTAAAGATAAACGTTTT
GACGATCTTTATTTATTACCTGCAGCACAAACGAGTGATAAATCAGCGGTAACACCTGAACAAATGGATGAATTAATACA
AGTATTACGTCAAGATTATGATTACATATTAATTGATTGTCCTGCGGGGATTGAGCAGGGATTTAAAAACGCGGTAGCTG
GTGCGGATAAAGCAATTGTCGTTACGACGCCAGAAGTATCCTCAATGCGCGATGCGGATCGTATTATCGGGCTTTTAGAA
AAAGAGGATATTGAACCACCGAAACTTGTTATTAATCGTGTGCGTAGTCATATGCTTCATGAACAGGATATGTTAGATGT
TGATGAAATCGTACGTACATTGTCAATCGAGCTTCTTGGTGTTGTCGAAGATGATGATGAAGTTATTCGTGCTACAAATA
CAGGTGAACCTGTAGCGTTGCAACCGAGCGGAAAAGCAGCGTTAGCTTATCGTAATATTGCAAGACGCTTGTTGGGTGAG
AATGTCCCATTACAAGCATTTGAACAAGAAAAGGTATCGGTATTTACAAAGATGAAAAACTTCTTTGGAATCCGTTAA

Upstream 100 bases:

>100_bases
CGTATATTAATGAGAACAATCACATTGTTGTCGATCGACTGCAACTTCTCACTCATCTTAGACCTAATTTAACAAAGTTA
GAAAGGGGAATTGTATAGCT

Downstream 100 bases:

>100_bases
AAGCACTTCGCATATTTGCGGAGTGCTTTCTTTTTTCTTCACACGAATATCTTCCTTTCCTAGCTCATACATATGTACAA
ACTGTATACAACTGTTTCTA

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MGEAIVITSGKGGVGKTTTSANIGTALALSGKKVCLIDTDIGLRNLDVVMGLENRIVFDLVDVVEGRCRLPQALIKDKRF
DDLYLLPAAQTSDKSAVTPEQMDELIQVLRQDYDYILIDCPAGIEQGFKNAVAGADKAIVVTTPEVSSMRDADRIIGLLE
KEDIEPPKLVINRVRSHMLHEQDMLDVDEIVRTLSIELLGVVEDDDEVIRATNTGEPVALQPSGKAALAYRNIARRLLGE
NVPLQAFEQEKVSVFTKMKNFFGIR

Sequences:

>Translated_265_residues
MGEAIVITSGKGGVGKTTTSANIGTALALSGKKVCLIDTDIGLRNLDVVMGLENRIVFDLVDVVEGRCRLPQALIKDKRF
DDLYLLPAAQTSDKSAVTPEQMDELIQVLRQDYDYILIDCPAGIEQGFKNAVAGADKAIVVTTPEVSSMRDADRIIGLLE
KEDIEPPKLVINRVRSHMLHEQDMLDVDEIVRTLSIELLGVVEDDDEVIRATNTGEPVALQPSGKAALAYRNIARRLLGE
NVPLQAFEQEKVSVFTKMKNFFGIR
>Mature_264_residues
GEAIVITSGKGGVGKTTTSANIGTALALSGKKVCLIDTDIGLRNLDVVMGLENRIVFDLVDVVEGRCRLPQALIKDKRFD
DLYLLPAAQTSDKSAVTPEQMDELIQVLRQDYDYILIDCPAGIEQGFKNAVAGADKAIVVTTPEVSSMRDADRIIGLLEK
EDIEPPKLVINRVRSHMLHEQDMLDVDEIVRTLSIELLGVVEDDDEVIRATNTGEPVALQPSGKAALAYRNIARRLLGEN
VPLQAFEQEKVSVFTKMKNFFGIR

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=272, Percent_Identity=47.4264705882353, Blast_Score=234, Evalue=4e-63,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29077; Mature: 28946

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEAIVITSGKGGVGKTTTSANIGTALALSGKKVCLIDTDIGLRNLDVVMGLENRIVFDL
CCCEEEEECCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCEEECCCCHHHHHH
VDVVEGRCRLPQALIKDKRFDDLYLLPAAQTSDKSAVTPEQMDELIQVLRQDYDYILIDC
HHHHCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
PAGIEQGFKNAVAGADKAIVVTTPEVSSMRDADRIIGLLEKEDIEPPKLVINRVRSHMLH
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EQDMLDVDEIVRTLSIELLGVVEDDDEVIRATNTGEPVALQPSGKAALAYRNIARRLLGE
HHCCCCHHHHHHHHHEEEEEEEECCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHCC
NVPLQAFEQEKVSVFTKMKNFFGIR
CCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEAIVITSGKGGVGKTTTSANIGTALALSGKKVCLIDTDIGLRNLDVVMGLENRIVFDL
CCEEEEECCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCEEECCCCHHHHHH
VDVVEGRCRLPQALIKDKRFDDLYLLPAAQTSDKSAVTPEQMDELIQVLRQDYDYILIDC
HHHHCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
PAGIEQGFKNAVAGADKAIVVTTPEVSSMRDADRIIGLLEKEDIEPPKLVINRVRSHMLH
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EQDMLDVDEIVRTLSIELLGVVEDDDEVIRATNTGEPVALQPSGKAALAYRNIARRLLGE
HHCCCCHHHHHHHHHEEEEEEEECCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHCC
NVPLQAFEQEKVSVFTKMKNFFGIR
CCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]