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The map label for this gene is nadA

Identifier: 49187320

GI number: 49187320

Start: 4235829

End: 4236935

Strand: Reverse

Name: nadA

Synonym: BAS4325

Alternate gene names: 49187320

Gene position: 4236935-4235829 (Counterclockwise)

Preceding gene: 49187321

Following gene: 49187319

Centisome position: 81.03

GC content: 38.21

Gene sequence:

>1107_bases
ATGAGTATTTTAGAAAAAGTACAACCGATTGAAACGATGTTACCAGAGCGTTATTACACGATGTCAACAGAAGATATGGA
AAAGCGGGTTCGTGAAATTAAAGAAAAAATGGGGGAAACGCTATTTATTCCAGGACATCATTACCAAAAAGATGAAGTGG
TACAATTTTCTGATGCGGCAGGAGATTCACTTCAGCTTGCGCAAGTTGCAGCGAGCAATAAAGAAGCGAAATATATTGTA
TTTTGCGGTGTACACTTTATGGCAGAAACAGCAGATATGTTAACAACAGATGAACAAGTTGTCATCTTACCAGATATGCG
TGCAGGTTGTTCGATGGCAGATATGGCAGATATTGAACAAACAGAAAGAGCATGGGAAGAGCTCACGAAATTATTTGGAG
ATACGATGATTCCGTTAACGTATGTAAACTCTACGGCTGCCATTAAAGCGTTTTGTGGTCGTAATGGCGGAGCAACAGTA
ACGTCTTCTAATGCTAAACAAATGGTATCTTGGGCGTTTACGCAAAAAGAGCGTCTCGTCTTTTTACCGGATCAACATTT
AGGGAGAAATACAGCGTACGACTTAGGTATCCCGTTAGATAAAATGGCAGTATGGGATCCACATACTGATTCATTAGAGT
ACGATGGAGATATAGAAGAAATTCAAGTGATTTTATGGAAAGGGCATTGTTCAGTTCACCAAAACTTTACAGTGAAAAAT
ATAGAGAATGTACGGAAAAATCATCCAGATATGAATATTATTGTACATCCGGAATGTTGCTATGAAGTTGTAGCTGCTTC
GGATTATGCAGGTTCAACGAAATACATTATTGATATGATTGAATCGGCTCCATCCGGAAGTAAATGGGCGATTGGTACAG
AAATGAATTTAGTGAACCGAATTATTCAACAACACCCAGATAAAGAAATTGTTTCACTTAATCCGTTTATGTGTCCATGT
TTAACGATGAACCGAATTGATTTGCCGCACTTATTATGGGCACTTGAAACGATAGAAAGAGGAGAAGAAATTAACGTTAT
TAGCGTAGATAAACAAGTAACTGAAGAAGCGGTTCTTGCATTAAATCGTATGTTAGAGCGTGTGTGA

Upstream 100 bases:

>100_bases
TTATATTTCACTTGGAGCGTTAACACATTCAGTGAAAGCACTTGATATTAGTTTTAATATTGAGGCGTAAGGAAAGTGGC
TTAGAGGGGGAGAAAGAAAT

Downstream 100 bases:

>100_bases
AGCAGCGGGATTCCCGTTGCTTTTTTTCATACATGTAATCATAACGAGAACGAAATGGGCATACATTGTTTTGAAGAAAT
CATTGTGATTTTTTTATCCC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKEAKYIV
FCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWEELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATV
TSSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKN
IENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPC
LTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV

Sequences:

>Translated_368_residues
MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKEAKYIV
FCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWEELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATV
TSSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKN
IENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPC
LTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV
>Mature_367_residues
SILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKEAKYIVF
CGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWEELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVT
SSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKNI
ENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPCL
TMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=354, Percent_Identity=27.4011299435028, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_BACAA (C3P9B5)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868714.1
- ProteinModelPortal:   C3P9B5
- SMR:   C3P9B5
- EnsemblBacteria:   EBBACT00000130207
- GeneID:   7850819
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4677
- GeneTree:   EBGT00050000002444
- ProtClustDB:   PRK09375
- GO:   GO:0005737
- HAMAP:   MF_00569
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 41626; Mature: 41495

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: BINDING 46-46 BINDING 63-63 BINDING 141-141 BINDING 162-162 BINDING 256-256 BINDING 273-273

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAA
CCHHHHCCHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEECCCC
GDSLQLAQVAASNKEAKYIVFCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQ
CCCHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
TERAWEELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKQMVSWAFTQKERLV
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCEE
FLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKN
ECCCHHCCCCCCEECCCCHHHEEEECCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCHHH
IENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNR
HHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHH
IIQQHPDKEIVSLNPFMCPCLTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLA
HHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
LNRMLERV
HHHHHHCC
>Mature Secondary Structure 
SILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAA
CHHHHCCHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEECCCC
GDSLQLAQVAASNKEAKYIVFCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQ
CCCHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
TERAWEELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKQMVSWAFTQKERLV
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCEE
FLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKN
ECCCHHCCCCCCEECCCCHHHEEEECCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCHHH
IENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNR
HHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHH
IIQQHPDKEIVSLNPFMCPCLTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLA
HHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
LNRMLERV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA