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The map label for this gene is ruvA

Identifier: 49187311

GI number: 49187311

Start: 4228224

End: 4228841

Strand: Reverse

Name: ruvA

Synonym: BAS4316

Alternate gene names: 49187311

Gene position: 4228841-4228224 (Counterclockwise)

Preceding gene: 49187313

Following gene: 49187310

Centisome position: 80.88

GC content: 39.16

Gene sequence:

>618_bases
TTGTTTGAATATGTTACAGGTTACGTGGAGTATGTAGGACCGGAATATGTCGTAATTGATCATAATGGAATTGGTTATCA
AATTTTCACACCGAATCCGTATGTATTTCAAAGAAGTAAGCAAGAAATCCGTGTCTATACATATCATTATGTGAGAGAAG
ATATTATGGCACTTTACGGGTTTAAAACACGTGAAGAGCGTTTATTATTTACAAAGTTGTTAGGGGTGTCTGGTATTGGA
CCAAAAGGTGCTCTTGCAATTTTAGCTTCTGGTCAAACAGGACAGGTCGTTCAAGCGATTGAACATGAAGACGAGAAGTT
TTTAGTGAAGTTCCCGGGCGTCGGAAAGAAAACAGCACGCCAAATGATTTTAGATTTAAAAGGAAAACTAGCAGACGTTG
TACCAGATGCATTTGTTGATTTATTCTCAGACGAAGAACGTTTTGATGAGAAGAAAGGTTCGTCAGCTGAGCTTGATGAG
GCGCTGGAAGCTCTGCGCGCACTTGGATACGCAGAACGAGAAGTTTCTCGCGTTGTACCAGAGTTATTAAAAGAATCATT
AACGACGGATCAGTATATTAAAAAGGCACTTAGTCTTTTACTAAATGGTAAGAGGTGA

Upstream 100 bases:

>100_bases
CAGAAGTTTTAAATGGAGAACATTTGTTGGGGTAGTCTCGCTTTTCTATCATTAAATATGTTAAAATGGAATACATGATT
TAAGAGGGAGAGATTGTATT

Downstream 100 bases:

>100_bases
GTATAATGGACGAACGTCTCCTTTCAGGGGAATCTGCATATGAAGATGCGGATTTAGAATATTCATTACGGCCACAGACG
CTCCGTCAGTATATTGGCCA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYGFKTREERLLFTKLLGVSGIG
PKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTARQMILDLKGKLADVVPDAFVDLFSDEERFDEKKGSSAELDE
ALEALRALGYAEREVSRVVPELLKESLTTDQYIKKALSLLLNGKR

Sequences:

>Translated_205_residues
MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYGFKTREERLLFTKLLGVSGIG
PKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTARQMILDLKGKLADVVPDAFVDLFSDEERFDEKKGSSAELDE
ALEALRALGYAEREVSRVVPELLKESLTTDQYIKKALSLLLNGKR
>Mature_205_residues
MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYGFKTREERLLFTKLLGVSGIG
PKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTARQMILDLKGKLADVVPDAFVDLFSDEERFDEKKGSSAELDE
ALEALRALGYAEREVSRVVPELLKESLTTDQYIKKALSLLLNGKR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=190, Percent_Identity=37.3684210526316, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_BACAA (C3P9A8)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868707.1
- ProteinModelPortal:   C3P9A8
- SMR:   C3P9A8
- EnsemblBacteria:   EBBACT00000127859
- GeneID:   7852377
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4668
- GeneTree:   EBGT00050000000364
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 23194; Mature: 23194

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYG
CCCHHHHHHHHCCCEEEEEECCCCEEEEECCCCCEECCCCCCEEEHHHHHHHHHHHHHHC
FKTREERLLFTKLLGVSGIGPKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTAR
CCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCHHHHH
QMILDLKGKLADVVPDAFVDLFSDEERFDEKKGSSAELDEALEALRALGYAEREVSRVVP
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHH
ELLKESLTTDQYIKKALSLLLNGKR
HHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYG
CCCHHHHHHHHCCCEEEEEECCCCEEEEECCCCCEECCCCCCEEEHHHHHHHHHHHHHHC
FKTREERLLFTKLLGVSGIGPKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTAR
CCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCHHHHH
QMILDLKGKLADVVPDAFVDLFSDEERFDEKKGSSAELDEALEALRALGYAEREVSRVVP
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHH
ELLKESLTTDQYIKKALSLLLNGKR
HHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA