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The map label for this gene is lip3 [H]

Identifier: 49187242

GI number: 49187242

Start: 4158726

End: 4159610

Strand: Direct

Name: lip3 [H]

Synonym: BAS4246

Alternate gene names: 49187242

Gene position: 4158726-4159610 (Clockwise)

Preceding gene: 49187241

Following gene: 49187245

Centisome position: 79.54

GC content: 33.67

Gene sequence:

>885_bases
TTGAAGCGATTTAGCTATTTTATGGTAGGTTGTCTTACTCTTACACTATTAGTAGGATGTAGTGCAGCAGAAAAGCCAGT
AGAACAAGTAAAACAAGTTAAAAATACACTTACAGCAAAACTAGCTACCGAGGAAAAAATGATAGAAATAGATGGTCAAA
CCATTTACTTCAAAAAGATTGGTAATGAAAAACCACCTTTACTTATGATCCATGGATTTGGAGGATCTTCAGATGGTTTT
CGAAAGATTTATTCAGATTTAGCAAAAGATCATACAATTATTTCTGTAGATGCTTTAGGATTCGGGCGCTCATCTAAACC
GATGGATTTTTACTATTCTTTCCCGACTCATGCAAATTTGTATTATAAATTAATGAAAAAACTAGGTTACGATTCGTTTG
CAATACTGGGACACTCAATGGGTGGAGAAATTTCTCTTAATTTAACATATTTATATCCTGAAGCCGTTACCCACCTTATT
TTAACTGACGCTACAGGCGGTGCTCATACACTAGTGAATAAACAAGGTTCACCAAAACCCCAGTTGTCGACTGATTTACA
TACTGTCTCTGCTATTGCAGATTATGATGAAAGCAAAGTGAAATTTAAACGTAATGATGAAGAACATTACAATAAAATGA
AATTATGGCCTAGACGTCTTCAAATCAATGCAAATGAAATACAACAACCAACTTTAATTATATGGGGAAGAAATGATAGT
AGCGTTTCATGGAAAGAAGGAGAAACGTATCATCAATTCTTAAAGAATAGTACTTTCCATATTATCGAAAAGGGTTATCA
TGCACCGTTTCGTCAAGAGCCACAAGAATTTGTAGGTTATGTAAAAGAATTCTTTAAAAACAATCCGATACAAGCTGAAA
AATAA

Upstream 100 bases:

>100_bases
TTCACCTCTTATGATAAAAAATGGTAGCCAACTTCCTGGAAATCGTAATATGCTATTTGCTATGATAGATACAGCGTTAT
GTTAGAAAGGGGACACCTAA

Downstream 100 bases:

>100_bases
CATAAACGGGTATCTCATTTTGAGATACCCGTTTTCATATATTAAGCAGCTTGCTTTTGGCGTTTTTGAGTTTTTGATCC
TAATACTTTTGGGATAACGA

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKRFSYFMVGCLTLTLLVGCSAAEKPVEQVKQVKNTLTAKLATEEKMIEIDGQTIYFKKIGNEKPPLLMIHGFGGSSDGF
RKIYSDLAKDHTIISVDALGFGRSSKPMDFYYSFPTHANLYYKLMKKLGYDSFAILGHSMGGEISLNLTYLYPEAVTHLI
LTDATGGAHTLVNKQGSPKPQLSTDLHTVSAIADYDESKVKFKRNDEEHYNKMKLWPRRLQINANEIQQPTLIIWGRNDS
SVSWKEGETYHQFLKNSTFHIIEKGYHAPFRQEPQEFVGYVKEFFKNNPIQAEK

Sequences:

>Translated_294_residues
MKRFSYFMVGCLTLTLLVGCSAAEKPVEQVKQVKNTLTAKLATEEKMIEIDGQTIYFKKIGNEKPPLLMIHGFGGSSDGF
RKIYSDLAKDHTIISVDALGFGRSSKPMDFYYSFPTHANLYYKLMKKLGYDSFAILGHSMGGEISLNLTYLYPEAVTHLI
LTDATGGAHTLVNKQGSPKPQLSTDLHTVSAIADYDESKVKFKRNDEEHYNKMKLWPRRLQINANEIQQPTLIIWGRNDS
SVSWKEGETYHQFLKNSTFHIIEKGYHAPFRQEPQEFVGYVKEFFKNNPIQAEK
>Mature_294_residues
MKRFSYFMVGCLTLTLLVGCSAAEKPVEQVKQVKNTLTAKLATEEKMIEIDGQTIYFKKIGNEKPPLLMIHGFGGSSDGF
RKIYSDLAKDHTIISVDALGFGRSSKPMDFYYSFPTHANLYYKLMKKLGYDSFAILGHSMGGEISLNLTYLYPEAVTHLI
LTDATGGAHTLVNKQGSPKPQLSTDLHTVSAIADYDESKVKFKRNDEEHYNKMKLWPRRLQINANEIQQPTLIIWGRNDS
SVSWKEGETYHQFLKNSTFHIIEKGYHAPFRQEPQEFVGYVKEFFKNNPIQAEK

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=113, Percent_Identity=34.5132743362832, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 33493; Mature: 33493

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFSYFMVGCLTLTLLVGCSAAEKPVEQVKQVKNTLTAKLATEEKMIEIDGQTIYFKKI
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEC
GNEKPPLLMIHGFGGSSDGFRKIYSDLAKDHTIISVDALGFGRSSKPMDFYYSFPTHANL
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCCCHH
YYKLMKKLGYDSFAILGHSMGGEISLNLTYLYPEAVTHLILTDATGGAHTLVNKQGSPKP
HHHHHHHHCCCCEEEEECCCCCEEEEEEEEECHHHHEEEEEECCCCCCEEEECCCCCCCC
QLSTDLHTVSAIADYDESKVKFKRNDEEHYNKMKLWPRRLQINANEIQQPTLIIWGRNDS
CCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCHHHEEECHHHCCCCEEEEEECCCC
SVSWKEGETYHQFLKNSTFHIIEKGYHAPFRQEPQEFVGYVKEFFKNNPIQAEK
CCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKRFSYFMVGCLTLTLLVGCSAAEKPVEQVKQVKNTLTAKLATEEKMIEIDGQTIYFKKI
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEC
GNEKPPLLMIHGFGGSSDGFRKIYSDLAKDHTIISVDALGFGRSSKPMDFYYSFPTHANL
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCCCHH
YYKLMKKLGYDSFAILGHSMGGEISLNLTYLYPEAVTHLILTDATGGAHTLVNKQGSPKP
HHHHHHHHCCCCEEEEECCCCCEEEEEEEEECHHHHEEEEEECCCCCCEEEECCCCCCCC
QLSTDLHTVSAIADYDESKVKFKRNDEEHYNKMKLWPRRLQINANEIQQPTLIIWGRNDS
CCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCHHHEEECHHHCCCCEEEEEECCCC
SVSWKEGETYHQFLKNSTFHIIEKGYHAPFRQEPQEFVGYVKEFFKNNPIQAEK
CCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2001407 [H]