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The map label for this gene is yqeV [H]

Identifier: 49187205

GI number: 49187205

Start: 4123487

End: 4124839

Strand: Reverse

Name: yqeV [H]

Synonym: BAS4209

Alternate gene names: 49187205

Gene position: 4124839-4123487 (Counterclockwise)

Preceding gene: 49187206

Following gene: 49187204

Centisome position: 78.89

GC content: 37.69

Gene sequence:

>1353_bases
ATGTCAACTGTTGCGTTCCATACGTTAGGTTGTAAAGTAAACCACTATGAAACAGAAGCCATTTGGCAATTGTTTAAACA
AGGTGGATATGAAAGAACGGAATATGAAAAGAAAGCTGATGTATATGTTATTAATACATGTACAGTAACAAATACGGGAG
ATAAGAAAAGTCGTCAAGTTATTAGACGTGCTGTTCGTCAAAACCCAGATGCAGTTATTTGTGTAACAGGATGTTATGCA
CAAACATCTCCAGCGGAAATTATGGCGATTCCAGGTGTAGATATTGTAGTTGGTACACAAGATCGTGAAAAGATGCTAGG
ATACATCGAAGAATTCCGTAAAGAGCGTCAACCGATTAATGCTGTCCGCAACATTATGAAAACACGTGTATACGAAGAAC
TGGATGTACCTTATTTCACGGATCGTACACGTGCATCTTTAAAAATACAAGAAGGTTGTAATAACTTCTGTACATTCTGT
ATTATTCCTTGGGCGCGTGGTTTAATGCGTTCTCGCGATGGGAAAGAAGTTATTAAACAAGCGCAGCAATTAGTAGATGC
AGGTTATAAAGAAATTGTATTAACAGGTATTCATACAGGTGGGTACGGTGAAGATATTAAAGATTATAACTTAGCTGGAT
TACTTCGTGATATGGAAGCAGAAGTAGGCGGATTAAAACGTCTTCGTATTTCTTCTATTGAAGCGAGTCAGATTTCAGAT
GAAGTAATTGAAGTGTTAGATAAGTCTGAAGTAGTTGTACGTCACTTACACATTCCGTTGCAATCTGGATCTAATACTGT
ATTAAAGCGTATGCGTCGTAAGTATACGATGGAATTCTTCCAAGAGCGTTTAGATCGTTTGAAAGAAGCGTTACCAGGTC
TTGCGATTACATCAGACGTAATCGTTGGTTTCCCAGGTGAAACAGAAGAAGAATTTATGGAAACATACAATTTCATTAAA
GAGAACCGCTTCTCTGAGTTACACGTGTTCCCTTACTCGAAACGTACAGGAACACCTGCAGCACGCATGGAAGACCAAGT
TCCTGAAGATGTAAAGAACGATCGTGTTCACCGTTTAATTGAATTATCTAATCAATTAGCGAAAGAGTACGCGTCACAGT
TTGAAGGAGAAGTACTTGAAATTATTCCAGAAGAACAATTTAAAGAGGGCGACCGTGAAGGCTTATATGTAGGTTATACA
GATAACTACTTGAAAATTGTATTTGAAGGATCAGAAGAATTAATTGGTAAACTAGTGAAAGTGAAAATCATGAAAGCTGG
TTATCCATATAACGAAGCGCAATTTGTTCGTGTTCTTGAAGATGATGTGAAAAAGGAATCAGCAAGCGCATAA

Upstream 100 bases:

>100_bases
ACCATGTAGTTTAGGACCAAGAATTTTAAGAACAGAAACGGCGCCGTTATACGCGTTAAGTGCTGCTTCGTATCATTTTG
AATTGATGGGGTGATGATCA

Downstream 100 bases:

>100_bases
AAAAAGCATGCAAACGGAAACGATTTGCATGCTTTCTTTTTTTGTGGAGAAGTTAAGTACTGAAAATGTACGAAATGCGT
AGTTGTTTCGTACGTTCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSTVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQVIRRAVRQNPDAVICVTGCYA
QTSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPINAVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFC
IIPWARGLMRSRDGKEVIKQAQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISD
EVIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDVIVGFPGETEEEFMETYNFIK
ENRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLIELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYT
DNYLKIVFEGSEELIGKLVKVKIMKAGYPYNEAQFVRVLEDDVKKESASA

Sequences:

>Translated_450_residues
MSTVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQVIRRAVRQNPDAVICVTGCYA
QTSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPINAVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFC
IIPWARGLMRSRDGKEVIKQAQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISD
EVIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDVIVGFPGETEEEFMETYNFIK
ENRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLIELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYT
DNYLKIVFEGSEELIGKLVKVKIMKAGYPYNEAQFVRVLEDDVKKESASA
>Mature_449_residues
STVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQVIRRAVRQNPDAVICVTGCYAQ
TSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPINAVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFCI
IPWARGLMRSRDGKEVIKQAQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISDE
VIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDVIVGFPGETEEEFMETYNFIKE
NRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLIELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYTD
NYLKIVFEGSEELIGKLVKVKIMKAGYPYNEAQFVRVLEDDVKKESASA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=443, Percent_Identity=30.9255079006772, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI28872784, Length=444, Percent_Identity=28.1531531531532, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI28872782, Length=444, Percent_Identity=28.1531531531532, Blast_Score=182, Evalue=7e-46,
Organism=Escherichia coli, GI1786882, Length=430, Percent_Identity=33.0232558139535, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1787057, Length=395, Percent_Identity=32.1518987341772, Blast_Score=187, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17553146, Length=469, Percent_Identity=27.2921108742004, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71996771, Length=275, Percent_Identity=31.6363636363636, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21356207, Length=441, Percent_Identity=28.5714285714286, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI19922432, Length=431, Percent_Identity=30.6264501160093, Blast_Score=178, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 51458; Mature: 51327

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQV
CCCEEEEEECCEECCCHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEEECCCCCHHHHHH
IRRAVRQNPDAVICVTGCYAQTSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPIN
HHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCHHH
AVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDGKEVIKQ
HHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
AQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISD
HHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHEEECCCCHHHHHH
EVIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDV
HHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCE
IVGFPGETEEEFMETYNFIKENRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLI
EEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHH
ELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYTDNYLKIVFEGSEELIGKLVK
HHHHHHHHHHHHHHCCCCEEECCCHHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHH
VKIMKAGYPYNEAQFVRVLEDDVKKESASA
HHHEECCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQV
CCEEEEEECCEECCCHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEEECCCCCHHHHHH
IRRAVRQNPDAVICVTGCYAQTSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPIN
HHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCHHH
AVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDGKEVIKQ
HHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
AQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISD
HHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHEEECCCCHHHHHH
EVIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDV
HHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCE
IVGFPGETEEEFMETYNFIKENRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLI
EEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHH
ELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYTDNYLKIVFEGSEELIGKLVK
HHHHHHHHHHHHHHCCCCEEECCCHHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHH
VKIMKAGYPYNEAQFVRVLEDDVKKESASA
HHHEECCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]