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The map label for this gene is glcK [H]

Identifier: 49187162

GI number: 49187162

Start: 4080937

End: 4081920

Strand: Reverse

Name: glcK [H]

Synonym: BAS4165

Alternate gene names: 49187162

Gene position: 4081920-4080937 (Counterclockwise)

Preceding gene: 49187163

Following gene: 49187160

Centisome position: 78.07

GC content: 39.84

Gene sequence:

>984_bases
ATGGAAGAGAAATGGTTAGTTGGTGTTGACCTTGGTGGTACAACGATTAAATTAGCATTTATTAATGTGTACGGTGAAAT
TTTACATAAGTGGGAAATCCCTACGAATACAAATGAGCAAGGAAAACATATTACACTTGATGTAGCGAAAGCTATTGATA
AAAAGTTAGAAGAGTTAGGTGAATTAAAAAGTAAGTTAATCGGTATTGGTATGGGAGCTCCTGGTCCTGTACACGTGGCG
TCTGGAATGATTTATGAAGCGGTTAACTTAGGATGGAAAAACTATCCGTTAAAAGATTTATTAGAAGTAGAAACAGGATT
ACCTGTTGTTATTGATAATGATGCAAATTTAGCGGCACTTGGTGAAATGTGGAAGGGTGCTGGTGAAGGAGCAAAAGATT
TAATTTGTATGACACTTGGCACTGGTGTTGGCGGCGGTGTAATTGCCAATGGTGAGATTGTACATGGCGTAAGCGGTGCT
GCTGGTGAGATTGGACACATTACAGTCGTTACAGAGAATGCTTTCCCATGTAATTGCGGGAAGTCTGGTTGCCTAGAAAC
TGTAGCATCTGCAACAGGTATTGTACGTGTTGCTATGCAGAAAATACAAGAGACTGATAAAGAAAGTATTCTACGTTCTA
TGTTAGCAGAAGAAGGGCGTATTACATCAAAAGACGTATTTGAAGCACATGGACAAGGTGATGAACTAGCAGGCGAAGTA
GTAGAAAAGGTAGCTTCTTATTTAGGATTAGCTGTAGCGAACCTTTCGAGCACGTTGAATCCAGAGAAAATTGTTATTGG
TGGAGGCGTTTCTAAAGCTGGAGATGCACTATTAGAACCAATTCAACGTTATTTCGAGCAATACGCTTTCTCACGTGCTG
TAAAGAGCACGAAGTTAGCTATTGCAACACTTGGTAATGATGCAGGTGTTATCGGAGGAGCTTGGCTTGTAAAAAAGCAC
AAATACGAAGCGAAGATGATATAA

Upstream 100 bases:

>100_bases
CAGCTAATCGATCCACAAGACTATCAAACAGCTTTATTTTTATTGAAGCAAGAAATTCAAAAAGAGCTAAATAAGAATTA
GATAAAGGTAGGTAAGCAAC

Downstream 100 bases:

>100_bases
GTTGTGAACTATGAAAAGAGGAAGGGAAACCCTTCCTCTTTTTGTGCGAAATCTGGATGAAGAATAATCTGTAAATGAAT
TAAGCTGCTGGTGGGTACCC

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTNTNEQGKHITLDVAKAIDKKLEELGELKSKLIGIGMGAPGPVHVA
SGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAALGEMWKGAGEGAKDLICMTLGTGVGGGVIANGEIVHGVSGA
AGEIGHITVVTENAFPCNCGKSGCLETVASATGIVRVAMQKIQETDKESILRSMLAEEGRITSKDVFEAHGQGDELAGEV
VEKVASYLGLAVANLSSTLNPEKIVIGGGVSKAGDALLEPIQRYFEQYAFSRAVKSTKLAIATLGNDAGVIGGAWLVKKH
KYEAKMI

Sequences:

>Translated_327_residues
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTNTNEQGKHITLDVAKAIDKKLEELGELKSKLIGIGMGAPGPVHVA
SGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAALGEMWKGAGEGAKDLICMTLGTGVGGGVIANGEIVHGVSGA
AGEIGHITVVTENAFPCNCGKSGCLETVASATGIVRVAMQKIQETDKESILRSMLAEEGRITSKDVFEAHGQGDELAGEV
VEKVASYLGLAVANLSSTLNPEKIVIGGGVSKAGDALLEPIQRYFEQYAFSRAVKSTKLAIATLGNDAGVIGGAWLVKKH
KYEAKMI
>Mature_327_residues
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTNTNEQGKHITLDVAKAIDKKLEELGELKSKLIGIGMGAPGPVHVA
SGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAALGEMWKGAGEGAKDLICMTLGTGVGGGVIANGEIVHGVSGA
AGEIGHITVVTENAFPCNCGKSGCLETVASATGIVRVAMQKIQETDKESILRSMLAEEGRITSKDVFEAHGQGDELAGEV
VEKVASYLGLAVANLSSTLNPEKIVIGGGVSKAGDALLEPIQRYFEQYAFSRAVKSTKLAIATLGNDAGVIGGAWLVKKH
KYEAKMI

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=271, Percent_Identity=31.3653136531365, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI4885285, Length=271, Percent_Identity=31.3653136531365, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI190014632, Length=271, Percent_Identity=31.3653136531365, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI298566315, Length=271, Percent_Identity=31.3653136531365, Blast_Score=111, Evalue=8e-25,
Organism=Escherichia coli, GI1787878, Length=279, Percent_Identity=33.6917562724014, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1786891, Length=316, Percent_Identity=30.0632911392405, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87081733, Length=323, Percent_Identity=30.030959752322, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787363, Length=275, Percent_Identity=28.3636363636364, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082127, Length=284, Percent_Identity=26.4084507042254, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082230, Length=283, Percent_Identity=29.3286219081272, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790522, Length=326, Percent_Identity=25.1533742331288, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34466; Mature: 34466

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTNTNEQGKHITLDVAKAIDKKLEELG
CCCCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
ELKSKLIGIGMGAPGPVHVASGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAAL
HHHHHHEEECCCCCCCHHHHCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCHHHH
GEMWKGAGEGAKDLICMTLGTGVGGGVIANGEIVHGVSGAAGEIGHITVVTENAFPCNCG
HHHHHCCCCCCHHEEEEEECCCCCCCEEECCEEEECCCCCCCCCEEEEEEECCCCCCCCC
KSGCLETVASATGIVRVAMQKIQETDKESILRSMLAEEGRITSKDVFEAHGQGDELAGEV
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHH
VEKVASYLGLAVANLSSTLNPEKIVIGGGVSKAGDALLEPIQRYFEQYAFSRAVKSTKLA
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IATLGNDAGVIGGAWLVKKHKYEAKMI
EEEECCCCCCCCHHHHEEHHCCCCCCC
>Mature Secondary Structure
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTNTNEQGKHITLDVAKAIDKKLEELG
CCCCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
ELKSKLIGIGMGAPGPVHVASGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAAL
HHHHHHEEECCCCCCCHHHHCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCHHHH
GEMWKGAGEGAKDLICMTLGTGVGGGVIANGEIVHGVSGAAGEIGHITVVTENAFPCNCG
HHHHHCCCCCCHHEEEEEECCCCCCCEEECCEEEECCCCCCCCCEEEEEEECCCCCCCCC
KSGCLETVASATGIVRVAMQKIQETDKESILRSMLAEEGRITSKDVFEAHGQGDELAGEV
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHH
VEKVASYLGLAVANLSSTLNPEKIVIGGGVSKAGDALLEPIQRYFEQYAFSRAVKSTKLA
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IATLGNDAGVIGGAWLVKKHKYEAKMI
EEEECCCCCCCCHHHHEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]