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The map label for this gene is pagR [H]

Identifier: 49187158

GI number: 49187158

Start: 4078103

End: 4078621

Strand: Direct

Name: pagR [H]

Synonym: BAS4161

Alternate gene names: 49187158

Gene position: 4078103-4078621 (Clockwise)

Preceding gene: 49187157

Following gene: 49187161

Centisome position: 78.0

GC content: 31.02

Gene sequence:

>519_bases
GTGTTACAAATATATCTATATCTTTCAATTTTTAAAACACATCGAAATTTTCACCCAAAAATGTCATTTTACAAAACCGT
GCTAAATCATCTACTTTATTTACATCAGGGTCTCTTTTCTTACAATTTCTTTACTTTAGGAATGTTTTTCTGCAACAACT
GTTTTCTTTTCTTTAATTTTTTGGTATGTATAGTATGGTATAACAGCTCACACGGAGGTGGAAAAAACATGTTAGAAACC
TTTCAAAAAGAAATAGAACTATATGAAAGCAATGCAGAATTATTGAAAGTACTTGCTCATCCTGTTCGCTTATGTATTGT
AAAAGGATTAATTGAACGTGGTCCAAGCAACGTTTCTACAATGTACACTGGCTTAAACATGCCACAATCTACAATTTCAC
AGCATTTAGCAAAATTAAAAAGTGCTAAAATCGTTTCAAGCGAAAGAAAAGGTTTGGAAATTTATTACAAAGTAGAAAAC
GAGACAATTATTCAACTCGTTCGCGTATTATTGGGTTAG

Upstream 100 bases:

>100_bases
CCTGTTTTATATTCTATATATAACATTATAATTCCTTTTTCATATTATTTTAAAAATTTTGTATATTCATTTGAAAGAAT
AAGAAAATCATGATAAAATT

Downstream 100 bases:

>100_bases
GGACTCATAAACAGAGAAAAAGGACGTATTTTATATTTTTTATCTCATATCTTTAATATAAATATATATCATGAGAGGAA
ATATATGATGCTACATAAGT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Protective antigen repressor [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MLQIYLYLSIFKTHRNFHPKMSFYKTVLNHLLYLHQGLFSYNFFTLGMFFCNNCFLFFNFLVCIVWYNSSHGGGKNMLET
FQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGLEIYYKVEN
ETIIQLVRVLLG

Sequences:

>Translated_172_residues
MLQIYLYLSIFKTHRNFHPKMSFYKTVLNHLLYLHQGLFSYNFFTLGMFFCNNCFLFFNFLVCIVWYNSSHGGGKNMLET
FQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGLEIYYKVEN
ETIIQLVRVLLG
>Mature_172_residues
MLQIYLYLSIFKTHRNFHPKMSFYKTVLNHLLYLHQGLFSYNFFTLGMFFCNNCFLFFNFLVCIVWYNSSHGGGKNMLET
FQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGLEIYYKVEN
ETIIQLVRVLLG

Specific function: Represses the expression of the pagA and atxA genes [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 20006; Mature: 20006

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQIYLYLSIFKTHRNFHPKMSFYKTVLNHLLYLHQGLFSYNFFTLGMFFCNNCFLFFNF
CEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVCIVWYNSSHGGGKNMLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVST
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
MYTGLNMPQSTISQHLAKLKSAKIVSSERKGLEIYYKVENETIIQLVRVLLG
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHC
>Mature Secondary Structure
MLQIYLYLSIFKTHRNFHPKMSFYKTVLNHLLYLHQGLFSYNFFTLGMFFCNNCFLFFNF
CEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVCIVWYNSSHGGGKNMLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVST
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
MYTGLNMPQSTISQHLAKLKSAKIVSSERKGLEIYYKVENETIIQLVRVLLG
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419943; 10515943; 12004073; 12067380; 10475965 [H]