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The map label for this gene is murG

Identifier: 49187152

GI number: 49187152

Start: 4068088

End: 4069146

Strand: Reverse

Name: murG

Synonym: BAS4155

Alternate gene names: 49187152

Gene position: 4069146-4068088 (Counterclockwise)

Preceding gene: 49187153

Following gene: 49187151

Centisome position: 77.82

GC content: 35.6

Gene sequence:

>1059_bases
ATGAAAAAAATAGTCTTTACAGGTGGCGGTTCGGCAGGGCATGTAACACCTAATTTAGCCATTATTCCATATTTAAAGGA
AGACAACTGGGACATTTCTTATATTGGTTCTCATCAAGGAATTGAGAAGACGATTATAGAAAAGGAAGATATTCCGTACT
ATAGTATTGCGAGTGGAAAGCTACGCCGTTATTTTGATTTAAAAAATATAAAAGATCCTTTTCTTGTGATGAAGGGTGTT
ATGGACGCGTATGTAAGGATTCGAAAACTAAAACCAGATGTGATTTTTTCAAAAGGTGGTTTCGTATCTGTACCAGTCGT
AATTGGAGGATGGCTAAATAGAGTACCAGTTTTATTACATGAGTCTGATATGACGCCAGGACTAGCAAATAAAATTGCGC
TCCGTTTCGCTTCAAAAATATTTGTTACATTTGAAGAAGCTGCGAAACATTTACCGAAAGAAAAAGTAATTTATACAGGG
TCTCCTGTACGTGAAGAAGTACTAAAGGGAGATCGTGAAAAAGCTTTAGCGTTTTTAGGTTTTTCACGTAAAAAGCCAGT
TATTACAATTATGGGAGGAAGTTTGGGCGCAAAAAAAATTAACGAAACGGTTCGAGAAGCGTTACCAGAACTTCTGAGAA
AATATCAAATTGTTCACCTTTGTGGAAAAGGTAATCTTGATGATAGTTTACAAAATAAAGAAGGATATAGACAATTTGAA
TATGTACACGGGGAACTGCCGGATATATTAGCGATAACAGATTTTGTTATTTCACGTGCGGGGTCCAACGCTATTTTTGA
GTTTTTAACATTGCAAAAGCCGATGCTTCTAATTCCGCTATCGAAATTTGCAAGTCGTGGAGACCAAATATTAAATGCAG
AATCATTTGAAAGGCAAGGATATGCCTCTGTACTGTATGAAGAAGATGTGACTGTCAATTCTCTTATAAAGCATGTTGAA
GAGTTATCTCATAATAATGAGGCATATAAAACCGCATTAAAAAAATATAATGGAAAAGAAGCGATTCAAACAATCATTCA
CCATATTTCAGAGGCATGA

Upstream 100 bases:

>100_bases
AGGGTTTATGATGGAACCAGAAGCATCTGTAACGGCTATGGTATTTTCTCACCCCGAGGCAAGATATTTTAGTGTATTAT
AGTCTAGAAGGGGGAGACGT

Downstream 100 bases:

>100_bases
TGAAACAATCATGCCTCTTTTAGTAGGATGAAAGATTCCAAGAAACGGTGTTTTTATGTTACAATAGCAAATGGTTAGTA
GGGAAATTCCAATTAATGAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 2

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKKIVFTGGGSAGHVTPNLAIIPYLKEDNWDISYIGSHQGIEKTIIEKEDIPYYSIASGKLRRYFDLKNIKDPFLVMKGV
MDAYVRIRKLKPDVIFSKGGFVSVPVVIGGWLNRVPVLLHESDMTPGLANKIALRFASKIFVTFEEAAKHLPKEKVIYTG
SPVREEVLKGDREKALAFLGFSRKKPVITIMGGSLGAKKINETVREALPELLRKYQIVHLCGKGNLDDSLQNKEGYRQFE
YVHGELPDILAITDFVISRAGSNAIFEFLTLQKPMLLIPLSKFASRGDQILNAESFERQGYASVLYEEDVTVNSLIKHVE
ELSHNNEAYKTALKKYNGKEAIQTIIHHISEA

Sequences:

>Translated_352_residues
MKKIVFTGGGSAGHVTPNLAIIPYLKEDNWDISYIGSHQGIEKTIIEKEDIPYYSIASGKLRRYFDLKNIKDPFLVMKGV
MDAYVRIRKLKPDVIFSKGGFVSVPVVIGGWLNRVPVLLHESDMTPGLANKIALRFASKIFVTFEEAAKHLPKEKVIYTG
SPVREEVLKGDREKALAFLGFSRKKPVITIMGGSLGAKKINETVREALPELLRKYQIVHLCGKGNLDDSLQNKEGYRQFE
YVHGELPDILAITDFVISRAGSNAIFEFLTLQKPMLLIPLSKFASRGDQILNAESFERQGYASVLYEEDVTVNSLIKHVE
ELSHNNEAYKTALKKYNGKEAIQTIIHHISEA
>Mature_352_residues
MKKIVFTGGGSAGHVTPNLAIIPYLKEDNWDISYIGSHQGIEKTIIEKEDIPYYSIASGKLRRYFDLKNIKDPFLVMKGV
MDAYVRIRKLKPDVIFSKGGFVSVPVVIGGWLNRVPVLLHESDMTPGLANKIALRFASKIFVTFEEAAKHLPKEKVIYTG
SPVREEVLKGDREKALAFLGFSRKKPVITIMGGSLGAKKINETVREALPELLRKYQIVHLCGKGNLDDSLQNKEGYRQFE
YVHGELPDILAITDFVISRAGSNAIFEFLTLQKPMLLIPLSKFASRGDQILNAESFERQGYASVLYEEDVTVNSLIKHVE
ELSHNNEAYKTALKKYNGKEAIQTIIHHISEA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=320, Percent_Identity=28.4375, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG2_BACAN (Q81JE6)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_846702.1
- RefSeq:   YP_021120.1
- RefSeq:   YP_030404.1
- ProteinModelPortal:   Q81JE6
- SMR:   Q81JE6
- EnsemblBacteria:   EBBACT00000012750
- EnsemblBacteria:   EBBACT00000017253
- EnsemblBacteria:   EBBACT00000022062
- GeneID:   1087934
- GeneID:   2816755
- GeneID:   2853063
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_4477
- KEGG:   bar:GBAA_4477
- KEGG:   bat:BAS4155
- TIGR:   BA_4477
- TIGR:   GBAA_4477
- GeneTree:   EBGT00050000001194
- HOGENOM:   HBG617076
- OMA:   HICGKGN
- ProtClustDB:   PRK12446
- BioCyc:   BANT260799:BAS4155-MONOMER
- BioCyc:   BANT261594:GBAA4477-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39508; Mature: 39508

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVFTGGGSAGHVTPNLAIIPYLKEDNWDISYIGSHQGIEKTIIEKEDIPYYSIASGK
CCEEEEECCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHHCCCCCCCEEEECCCC
LRRYFDLKNIKDPFLVMKGVMDAYVRIRKLKPDVIFSKGGFVSVPVVIGGWLNRVPVLLH
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEHHHHCCHHHCCCEEEE
ESDMTPGLANKIALRFASKIFVTFEEAAKHLPKEKVIYTGSPVREEVLKGDREKALAFLG
CCCCCCCHHHHHHHHHHHHHHEEHHHHHHHCCCCCEEECCCHHHHHHHCCCHHHHHHHHC
FSRKKPVITIMGGSLGAKKINETVREALPELLRKYQIVHLCGKGNLDDSLQNKEGYRQFE
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHCHHHHHHHH
YVHGELPDILAITDFVISRAGSNAIFEFLTLQKPMLLIPLSKFASRGDQILNAESFERQG
HHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEHHHHHCCCCHHCCCHHHHHCC
YASVLYEEDVTVNSLIKHVEELSHNNEAYKTALKKYNGKEAIQTIIHHISEA
CHHEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIVFTGGGSAGHVTPNLAIIPYLKEDNWDISYIGSHQGIEKTIIEKEDIPYYSIASGK
CCEEEEECCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHHCCCCCCCEEEECCCC
LRRYFDLKNIKDPFLVMKGVMDAYVRIRKLKPDVIFSKGGFVSVPVVIGGWLNRVPVLLH
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEHHHHCCHHHCCCEEEE
ESDMTPGLANKIALRFASKIFVTFEEAAKHLPKEKVIYTGSPVREEVLKGDREKALAFLG
CCCCCCCHHHHHHHHHHHHHHEEHHHHHHHCCCCCEEECCCHHHHHHHCCCHHHHHHHHC
FSRKKPVITIMGGSLGAKKINETVREALPELLRKYQIVHLCGKGNLDDSLQNKEGYRQFE
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHCHHHHHHHH
YVHGELPDILAITDFVISRAGSNAIFEFLTLQKPMLLIPLSKFASRGDQILNAESFERQG
HHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEHHHHHCCCCHHCCCHHHHHCC
YASVLYEEDVTVNSLIKHVEELSHNNEAYKTALKKYNGKEAIQTIIHHISEA
CHHEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629