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The map label for this gene is ydjN [C]

Identifier: 49187145

GI number: 49187145

Start: 4063815

End: 4065209

Strand: Direct

Name: ydjN [C]

Synonym: BAS4148

Alternate gene names: 49187145

Gene position: 4063815-4065209 (Clockwise)

Preceding gene: 49187144

Following gene: 49187148

Centisome position: 77.72

GC content: 35.77

Gene sequence:

>1395_bases
ATGAATACACTGCTTGTCGGAATTAACGTTGCAGTCATGCTCATTTTAGTTGGCGTATTATATTATATGCAACGTAAGCA
TGTATCTTTTAATAAACGTGTATTTACTGCTTTAGGAATCGGAATTATCTTCGGTCTTATATTACAATTTATTTATGAAC
CTACTTCTAAAGTCATTATTGAATCAAATACTTGGTTTGGCTTAATTGGTAGCGGTTATGTGAAATTACTTCAAATGATC
GTTATGCCACTTATTTTAGTATCTATCATTTCAGCATTTACAAAATTACAGTTAACGAAAAATCTTGGTAAAATTAGTGG
TCTTATTATCGGAATTTTAATTCTTACTACAGGAATTGCTGCAGCTGTCGGTATCGCTGCAAGTGCAGGATTTGATGTAT
CTGCAACAGGCCTGCAACAAGGTGATGCAGAATCTGCTCGTCTGAAGCTAGTTGAAGAAAGATTTACTTCTATTGAAAAA
ACAACAATTCCAGATAAATTATTAGAACTATTGCCTACAAATCCATTTCTTGATTTAACAGGCGCTCGTCCAACATCAAC
AATTTCTGTTGTAATATTTGCAGCATTTATCGGTATCGCCTTTATAGGTGTAAAACGAAAATATCCAGAACAAGCAGAGC
TATTTAAGAAAATGCTTGATGCTGTATATGCAATTGTAATGCGTATGGTAACATTAATTTTACGTCTTACTCCATATGGT
GTATTAGCTCTTATGGCAAAAACAGTTGCTGGTAGCGACATAAATGCTATTTTAAAACTTGGTAACTTCGTGTTAGCGTC
TTACGTAGCACTTATCGTAATGTTCGTTATCCACTTATTATTAATTGCTCTATCTGGTTTAAATCCAATTCAATATTTAA
AAAAGGTATTCCCTGTATTAACATTCGCATTCACATCTCGCTCTAGTGCCGGTGCAATGCCATTAAATATTGAAGCACAA
AAAGAAAAACTTGGTATTTCTGAAGGAATCGCTAACTTCGCAGCATCATTTGGAGTATCTATCGGACAAAATGGTTGCGC
AGGTATTTACCCAGCAATGCTTGCAATGATGGTCGCTCCAACTGTTGGAATTGATCCATTACAACCACAATTTATTTTAA
CTTTAATCGCTGTCGTTGCTATTAGCTCATTCGGTGTTGCCGGCGTTGGTGGCGGTGCAACATTCGCAGCATTAATCGTA
CTATCTACAATGAACTTACCAATCGGTATTGTCGCTCTTGTTATCTCAGTTGAACCATTAATCGATATGGGTCGTACAGC
TCTTAACGTAAGTGGTTCTATGACAGCAGGTCTTATTTCTAGTAAATGGCTTGGTGAATTAGATCAAGATACGTACAATC
AAGATGATACAAAAACTGGTGAGATTGCTTCATAA

Upstream 100 bases:

>100_bases
CATTTTGCCATCTTTTTTTTAATTCCGGAATTCCCTAGTTGACTTATAGGTTTTATTGATTTATATTCTATATAACAGAT
TGGAATTAGGGGGAATCATC

Downstream 100 bases:

>100_bases
TAAAAAGGACGCTAACAAAAATGTTAGCGTCCTTTTTTAGTTCTTTTCATCTTCCTCTTTATCTTTTATACATAAGGCAT
AACATATTGTTTCAAACACT

Product: sodium:dicarboxylate symporter family protein

Products: NA

Alternate protein names: Transporter of cystine tcyP

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNTLLVGINVAVMLILVGVLYYMQRKHVSFNKRVFTALGIGIIFGLILQFIYEPTSKVIIESNTWFGLIGSGYVKLLQMI
VMPLILVSIISAFTKLQLTKNLGKISGLIIGILILTTGIAAAVGIAASAGFDVSATGLQQGDAESARLKLVEERFTSIEK
TTIPDKLLELLPTNPFLDLTGARPTSTISVVIFAAFIGIAFIGVKRKYPEQAELFKKMLDAVYAIVMRMVTLILRLTPYG
VLALMAKTVAGSDINAILKLGNFVLASYVALIVMFVIHLLLIALSGLNPIQYLKKVFPVLTFAFTSRSSAGAMPLNIEAQ
KEKLGISEGIANFAASFGVSIGQNGCAGIYPAMLAMMVAPTVGIDPLQPQFILTLIAVVAISSFGVAGVGGGATFAALIV
LSTMNLPIGIVALVISVEPLIDMGRTALNVSGSMTAGLISSKWLGELDQDTYNQDDTKTGEIAS

Sequences:

>Translated_464_residues
MNTLLVGINVAVMLILVGVLYYMQRKHVSFNKRVFTALGIGIIFGLILQFIYEPTSKVIIESNTWFGLIGSGYVKLLQMI
VMPLILVSIISAFTKLQLTKNLGKISGLIIGILILTTGIAAAVGIAASAGFDVSATGLQQGDAESARLKLVEERFTSIEK
TTIPDKLLELLPTNPFLDLTGARPTSTISVVIFAAFIGIAFIGVKRKYPEQAELFKKMLDAVYAIVMRMVTLILRLTPYG
VLALMAKTVAGSDINAILKLGNFVLASYVALIVMFVIHLLLIALSGLNPIQYLKKVFPVLTFAFTSRSSAGAMPLNIEAQ
KEKLGISEGIANFAASFGVSIGQNGCAGIYPAMLAMMVAPTVGIDPLQPQFILTLIAVVAISSFGVAGVGGGATFAALIV
LSTMNLPIGIVALVISVEPLIDMGRTALNVSGSMTAGLISSKWLGELDQDTYNQDDTKTGEIAS
>Mature_464_residues
MNTLLVGINVAVMLILVGVLYYMQRKHVSFNKRVFTALGIGIIFGLILQFIYEPTSKVIIESNTWFGLIGSGYVKLLQMI
VMPLILVSIISAFTKLQLTKNLGKISGLIIGILILTTGIAAAVGIAASAGFDVSATGLQQGDAESARLKLVEERFTSIEK
TTIPDKLLELLPTNPFLDLTGARPTSTISVVIFAAFIGIAFIGVKRKYPEQAELFKKMLDAVYAIVMRMVTLILRLTPYG
VLALMAKTVAGSDINAILKLGNFVLASYVALIVMFVIHLLLIALSGLNPIQYLKKVFPVLTFAFTSRSSAGAMPLNIEAQ
KEKLGISEGIANFAASFGVSIGQNGCAGIYPAMLAMMVAPTVGIDPLQPQFILTLIAVVAISSFGVAGVGGGATFAALIV
LSTMNLPIGIVALVISVEPLIDMGRTALNVSGSMTAGLISSKWLGELDQDTYNQDDTKTGEIAS

Specific function: Mediates uptake of L-cystine, the oxidized form of L- cysteine

COG id: COG1823

COG function: function code R; Predicted Na+/dicarboxylate symporter

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI5032093, Length=388, Percent_Identity=26.0309278350515, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI223468564, Length=279, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI223468566, Length=259, Percent_Identity=27.027027027027, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI40254478, Length=328, Percent_Identity=28.0487804878049, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI21314632, Length=441, Percent_Identity=24.0362811791383, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI169790839, Length=467, Percent_Identity=24.6252676659529, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4827012, Length=268, Percent_Identity=26.1194029850746, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI194239697, Length=471, Percent_Identity=22.5053078556263, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI66773030, Length=308, Percent_Identity=26.2987012987013, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788024, Length=449, Percent_Identity=54.3429844097996, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1789947, Length=447, Percent_Identity=23.7136465324385, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790514, Length=431, Percent_Identity=24.3619489559165, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71983106, Length=436, Percent_Identity=23.1651376146789, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71983099, Length=436, Percent_Identity=23.1651376146789, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17537407, Length=450, Percent_Identity=24, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193206654, Length=467, Percent_Identity=24.4111349036403, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17541374, Length=446, Percent_Identity=24.4394618834081, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI193206505, Length=418, Percent_Identity=22.0095693779904, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71996953, Length=471, Percent_Identity=23.5668789808917, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583025, Length=404, Percent_Identity=25.4950495049505, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17137668, Length=404, Percent_Identity=25.4950495049505, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583023, Length=404, Percent_Identity=25.4950495049505, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TCYP_BACAH (A0RIM4)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_896574.1
- ProteinModelPortal:   A0RIM4
- EnsemblBacteria:   EBBACT00000069572
- GeneID:   4544919
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_3843
- eggNOG:   COG1823
- GeneTree:   EBGT00070000032022
- HOGENOM:   HBG739804
- ProtClustDB:   CLSK886937
- BioCyc:   BTHU412694:BALH_3843-MONOMER
- InterPro:   IPR001991
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 49257; Mature: 49257

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15abab7c)-; HASH(0x156157e0)-; HASH(0x15e11230)-; HASH(0x166e61e8)-; HASH(0x15b7987c)-; HASH(0x166e3404)-; HASH(0x166e36e0)-; HASH(0x166e5e4c)-; HASH(0x159332c0)-; HASH(0x166b7650)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLLVGINVAVMLILVGVLYYMQRKHVSFNKRVFTALGIGIIFGLILQFIYEPTSKVII
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ESNTWFGLIGSGYVKLLQMIVMPLILVSIISAFTKLQLTKNLGKISGLIIGILILTTGIA
ECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVGIAASAGFDVSATGLQQGDAESARLKLVEERFTSIEKTTIPDKLLELLPTNPFLDLT
HHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEECC
GARPTSTISVVIFAAFIGIAFIGVKRKYPEQAELFKKMLDAVYAIVMRMVTLILRLTPYG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
VLALMAKTVAGSDINAILKLGNFVLASYVALIVMFVIHLLLIALSGLNPIQYLKKVFPVL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TFAFTSRSSAGAMPLNIEAQKEKLGISEGIANFAASFGVSIGQNGCAGIYPAMLAMMVAP
HHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
TVGIDPLQPQFILTLIAVVAISSFGVAGVGGGATFAALIVLSTMNLPIGIVALVISVEPL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IDMGRTALNVSGSMTAGLISSKWLGELDQDTYNQDDTKTGEIAS
HHCCCHHEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MNTLLVGINVAVMLILVGVLYYMQRKHVSFNKRVFTALGIGIIFGLILQFIYEPTSKVII
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ESNTWFGLIGSGYVKLLQMIVMPLILVSIISAFTKLQLTKNLGKISGLIIGILILTTGIA
ECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVGIAASAGFDVSATGLQQGDAESARLKLVEERFTSIEKTTIPDKLLELLPTNPFLDLT
HHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEECC
GARPTSTISVVIFAAFIGIAFIGVKRKYPEQAELFKKMLDAVYAIVMRMVTLILRLTPYG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
VLALMAKTVAGSDINAILKLGNFVLASYVALIVMFVIHLLLIALSGLNPIQYLKKVFPVL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TFAFTSRSSAGAMPLNIEAQKEKLGISEGIANFAASFGVSIGQNGCAGIYPAMLAMMVAP
HHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
TVGIDPLQPQFILTLIAVVAISSFGVAGVGGGATFAALIVLSTMNLPIGIVALVISVEPL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IDMGRTALNVSGSMTAGLISSKWLGELDQDTYNQDDTKTGEIAS
HHCCCHHEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA