Click here to switch to the map view.

The map label for this gene is ykkD [H]

Identifier: 49187114

GI number: 49187114

Start: 4042795

End: 4043109

Strand: Direct

Name: ykkD [H]

Synonym: BAS4116

Alternate gene names: 49187114

Gene position: 4042795-4043109 (Clockwise)

Preceding gene: 49187113

Following gene: 49187115

Centisome position: 77.32

GC content: 42.54

Gene sequence:

>315_bases
ATGGCTTGGGTATTTTTAATTCTAGCTGGTATTTGTGAAATTATTGGTGTACTCTTTATGAAAGTAGCCACTGAAAAGAA
AAGCTGGGCACCAAAAGTTATTTTAATCGCTAACTTCGGCGTAAGCTTCTTCTTCTTATCCCTTGCGATGAACACATTAC
CGATGGGAACTGCTTACGCGATTTGGACTGGAATCGGAACTGCCGGAAGTGCACTTCTAGGCATCCTTATTTTCCGCGAA
TCAGCGGATTGGCGTCGTCTTGCTTTCTTAAGCTGCATTCTATGCGGCGCTGTTGGCTTAAAACTATTAAGCTAA

Upstream 100 bases:

>100_bases
TTCTCTATCGTAAAAGTATTATTAATTGGTTTAATCTTCTTCGGCGTAATTGGTTTAAAACGAGTAACAGAAGAAAAAGA
AGCGAAGGAGGCCGCATAAA

Downstream 100 bases:

>100_bases
CGTGAGGTGAATGTCATGTGGAAAGAAAAAGGGAAGCAACTGTTAGCATGGATCACGCTTGGTATCGTCATTCTACTGCA
AATTAGTTTTCATATAATAG

Product: sugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MAWVFLILAGICEIIGVLFMKVATEKKSWAPKVILIANFGVSFFFLSLAMNTLPMGTAYAIWTGIGTAGSALLGILIFRE
SADWRRLAFLSCILCGAVGLKLLS

Sequences:

>Translated_104_residues
MAWVFLILAGICEIIGVLFMKVATEKKSWAPKVILIANFGVSFFFLSLAMNTLPMGTAYAIWTGIGTAGSALLGILIFRE
SADWRRLAFLSCILCGAVGLKLLS
>Mature_103_residues
AWVFLILAGICEIIGVLFMKVATEKKSWAPKVILIANFGVSFFFLSLAMNTLPMGTAYAIWTGIGTAGSALLGILIFRES
ADWRRLAFLSCILCGAVGLKLLS

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=43.1372549019608, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11232; Mature: 11101

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWVFLILAGICEIIGVLFMKVATEKKSWAPKVILIANFGVSFFFLSLAMNTLPMGTAYA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHH
IWTGIGTAGSALLGILIFRESADWRRLAFLSCILCGAVGLKLLS
HHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWVFLILAGICEIIGVLFMKVATEKKSWAPKVILIANFGVSFFFLSLAMNTLPMGTAYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHH
IWTGIGTAGSALLGILIFRESADWRRLAFLSCILCGAVGLKLLS
HHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA