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The map label for this gene is rbsR [H]

Identifier: 49187011

GI number: 49187011

Start: 3951142

End: 3952005

Strand: Reverse

Name: rbsR [H]

Synonym: BAS4013

Alternate gene names: 49187011

Gene position: 3952005-3951142 (Counterclockwise)

Preceding gene: 49187012

Following gene: 49187008

Centisome position: 75.58

GC content: 32.87

Gene sequence:

>864_bases
GTGGCAACTATACGTGATGTTGCAAAATTGGCAGGTGTTTCAGTCGCAACCGTTTCACGAGTTATGAATGAAAAAGGATA
CGTTCATGAGGACACAGTAAAACAAGTAAAGGAAGCAATTGAGGAGTTACGTTATAGGCCAAATAGTGCAGCAAAGCCAT
TATTTAAAGAGAATTCAACAATAATTGCATTACTTGTAGATAATTTATATAATCCATCAAACATCACTTTGCTACATTGT
ATTGAGGAAATAGCATATAAAGAAGGATATCAAATCATTGTTTGTAATATAGAGAATAAAGATAGATGCATACATATGTT
GAAGGAAAATAACGTTGCAGGTGTTATTTTGACAAGATCGGTTTTTAAAAGTATAGGAGAAATTCCACTTCCGTTTGTTG
TGATTGATGAAAAAAAATCGCATGTAAACTATTATGAAAGTGGACAAAGAGCGGTTTCTTTATTAAAAGAAAAAGGCTGT
CACTTCCTTGCTTATTTCGGTGAGGGAGAAGATAGTGAAGAAATGGAAAATCGCATATCAGGATTTTTAGATGCTGTTTG
GGAGGGAGGAATCTCTTATCGAGAAGTATGTGTACAAGGATATACGAATAAACAGTTTATTACATTATTGCGAAACAATC
CGTATATAGATGGAATTGTAACTGAAAGTGATAAGGTTACTTTTGAGTTAATTCAAGCAGCAAAAAATTTAAATATCCGT
ATACCGGATAAATTAAAAATTATTGGACTGAACGGGAGTATAGACAGTGAGTGGATAGGGTCGTCATTTATGAAAATTGA
AAGTTGTATCGAAGAAAATGGGGAAATAGCGTTGCAACAATTAAAAGAAAAAATAAAAAAGTAA

Upstream 100 bases:

>100_bases
ATGTAACAATTTTCAGAAATATAAGTCATTAGCCTTGACGAATATTGTAATTTAGGTTACCGTAAAATTGTAATCTATTA
CCATATTAAGGGGTGACGAT

Downstream 100 bases:

>100_bases
AAGGTGCGTATAAAACGCACCTTTTATAATGTAATCGCGGCAATAAAGCCAAATATAAGTAAAGGTATATTGTAATGTAG
AAAAGTTGGTACACATGTAT

Product: LacI family sugar-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MATIRDVAKLAGVSVATVSRVMNEKGYVHEDTVKQVKEAIEELRYRPNSAAKPLFKENSTIIALLVDNLYNPSNITLLHC
IEEIAYKEGYQIIVCNIENKDRCIHMLKENNVAGVILTRSVFKSIGEIPLPFVVIDEKKSHVNYYESGQRAVSLLKEKGC
HFLAYFGEGEDSEEMENRISGFLDAVWEGGISYREVCVQGYTNKQFITLLRNNPYIDGIVTESDKVTFELIQAAKNLNIR
IPDKLKIIGLNGSIDSEWIGSSFMKIESCIEENGEIALQQLKEKIKK

Sequences:

>Translated_287_residues
MATIRDVAKLAGVSVATVSRVMNEKGYVHEDTVKQVKEAIEELRYRPNSAAKPLFKENSTIIALLVDNLYNPSNITLLHC
IEEIAYKEGYQIIVCNIENKDRCIHMLKENNVAGVILTRSVFKSIGEIPLPFVVIDEKKSHVNYYESGQRAVSLLKEKGC
HFLAYFGEGEDSEEMENRISGFLDAVWEGGISYREVCVQGYTNKQFITLLRNNPYIDGIVTESDKVTFELIQAAKNLNIR
IPDKLKIIGLNGSIDSEWIGSSFMKIESCIEENGEIALQQLKEKIKK
>Mature_286_residues
ATIRDVAKLAGVSVATVSRVMNEKGYVHEDTVKQVKEAIEELRYRPNSAAKPLFKENSTIIALLVDNLYNPSNITLLHCI
EEIAYKEGYQIIVCNIENKDRCIHMLKENNVAGVILTRSVFKSIGEIPLPFVVIDEKKSHVNYYESGQRAVSLLKEKGCH
FLAYFGEGEDSEEMENRISGFLDAVWEGGISYREVCVQGYTNKQFITLLRNNPYIDGIVTESDKVTFELIQAAKNLNIRI
PDKLKIIGLNGSIDSEWIGSSFMKIESCIEENGEIALQQLKEKIKK

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=311, Percent_Identity=25.7234726688103, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787948, Length=317, Percent_Identity=24.6056782334385, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790715, Length=308, Percent_Identity=24.3506493506494, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789202, Length=288, Percent_Identity=24.3055555555556, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787580, Length=277, Percent_Identity=26.7148014440433, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789068, Length=280, Percent_Identity=26.4285714285714, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994940, Length=305, Percent_Identity=23.9344262295082, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788474, Length=274, Percent_Identity=26.2773722627737, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787906, Length=261, Percent_Identity=25.6704980842912, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786268, Length=183, Percent_Identity=28.4153005464481, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790369, Length=308, Percent_Identity=23.7012987012987, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786540, Length=279, Percent_Identity=24.7311827956989, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 32399; Mature: 32267

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIRDVAKLAGVSVATVSRVMNEKGYVHEDTVKQVKEAIEELRYRPNSAAKPLFKENST
CCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCE
IIALLVDNLYNPSNITLLHCIEEIAYKEGYQIIVCNIENKDRCIHMLKENNVAGVILTRS
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCEEEEEHHH
VFKSIGEIPLPFVVIDEKKSHVNYYESGQRAVSLLKEKGCHFLAYFGEGEDSEEMENRIS
HHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
GFLDAVWEGGISYREVCVQGYTNKQFITLLRNNPYIDGIVTESDKVTFELIQAAKNLNIR
HHHHHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHCCCEE
IPDKLKIIGLNGSIDSEWIGSSFMKIESCIEENGEIALQQLKEKIKK
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ATIRDVAKLAGVSVATVSRVMNEKGYVHEDTVKQVKEAIEELRYRPNSAAKPLFKENST
CCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCE
IIALLVDNLYNPSNITLLHCIEEIAYKEGYQIIVCNIENKDRCIHMLKENNVAGVILTRS
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCEEEEEHHH
VFKSIGEIPLPFVVIDEKKSHVNYYESGQRAVSLLKEKGCHFLAYFGEGEDSEEMENRIS
HHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
GFLDAVWEGGISYREVCVQGYTNKQFITLLRNNPYIDGIVTESDKVTFELIQAAKNLNIR
HHHHHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHCCCEE
IPDKLKIIGLNGSIDSEWIGSSFMKIESCIEENGEIALQQLKEKIKK
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]